MetaCyc Pathway: pseudouridine degradation in Escherichia coli BW25113
Reactions and Genes | LB Aerobic with Oxytetracycline 0.00000125 mM |
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Pseudouridine kinase: pseudouridine + ATP→pseudouridine 5'-phosphate + ADP + H+ (EC 2.7.1.83) | |
b2160 (yeiI) | -0.1 |
b2166 (yeiC) | -0.2 |
Pseudouridylate synthase (in reverse): pseudouridine 5'-phosphate + H2O→uracil + D-ribofuranose 5-phosphate (EC 4.2.1.70) | |
b0058 (rluA) | -0.4 |
b1086 (rluC) | +0.2 |
b1135 (ymfC) | +0.3 |
b1269 (rluB) | +0.7 |
b2165 (yeiN) | -0.7 |
b2183 (rsuA) | +1.4 |
b2318 (truA) | -0.6 |
b2594 (rluD) | N.D. |
b2791 (yqcB) | +0.0 |
b3166 (truB) | -0.3 |
b4022 (yjbC) | -0.1 |
Links:
- Pathway details at MetaCyc
- Fitness data for 13 genes
- All MetaCyc pathways for Escherichia coli BW25113
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information