MetaCyc Pathway: benzoate biosynthesis III (CoA-dependent, non-β-oxidative) in Pseudomonas putida KT2440

Reactions and Genes	L-Valine (C)
Phenylalanine ammonia-lyase: L-phenylalanine→trans-cinnamate + ammonium (EC 4.3.1.24; 4.3.1.25; 5.4.3.10)
No genes
trans-cinnamate + ATP + coenzyme A→(E)-cinnamoyl-CoA + AMP + diphosphate
No genes
Enoyl-CoA hydratase (in reverse): (E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
PP_1412	+0.2
PP_1845	+0.5
PP_2047	+0.2
PP_2136	+0.0
PP_2217	-4.5
PP_3283	-0.1
PP_3284	+0.1
PP_3358	+0.0
PP_3491	-5.0
PP_3726	-0.2
PP_3732	+0.5
PP_4030	-0.1
(S)-3-hydroxy-3-phenylpropanoyl-CoA→benzaldehyde + acetyl-CoA
No genes
Benzaldehyde dehydrogenase (NAD(+)): benzaldehyde + NAD+ + H2O→benzoate + NADH + 2 H+ (EC 1.2.1.28)
PP_3357	+0.2

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information