Updated annotations for Pontibacter actiniarum KMM 6156, DSM 19842
2 genes with updated (or confirmed) annotations:
CA264_07430 : DNA repair nuclease with dnaQ and GIY-YIG domains
Original description: DNA polymerase III subunit epsilon
SEED: DNA polymerase III epsilon subunit (EC 2.7.7.7)
KEGG: no annotation
Rationale: # Specifically important in stress Cisplatin. Contains a domain that is similar to DnaQ (the epsilon subunit of replicative DNA polymerase which is the exonuclease for proofreading) as well as a GIY-YIG nuclease domain.This protein is often misannotated as DnaQ, but the proofreading activity of the replicative DNA polymerase seems to reside in the same polypeptide as the catalytic subunit (see discussion in PMC3919608).
CA264_14900 : uvrA paralog in Bacteroidetes
Original description: excinuclease ABC subunit A
SEED: Excinuclease ABC subunit A paralog in greater Bacteroides group
KEGG: excinuclease ABC subunit A
Rationale: # Very important for resisting cisplatin. Both the "standard" uvrA and this gene were important for cisplatin resistance. (SEED_correct)
Or download reannotations for Pontibacter actiniarum KMM 6156, DSM 19842 or for all organisms as tab-delimited tables