Fitness data for EFB2_00454 in Escherichia fergusonii Becca

Siroheme synthase
SEED: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
KEGG: uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.1)


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group condition fitness t score  
no phage control BHIS_CaCl2 no phage control -0.5 -2.0 compare
phage mixed community phage mixed community; hk phage cocktail 1 MOI; stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 2) -0.3 -1.9 compare
phage monoculture BHIS_CaCl2 with hk phage cocktail 1 MOI -0.3 -1.9 compare
phage mixed community phage mixed community; hk phage cocktail 1 MOI; stool-derived community from humanized mice (condition: pre-antibiotic, standard diet, mouse 2) -0.3 -1.7 compare
phage mixed community phage mixed community; hk phage cocktail 1 MOI; stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 1) -0.2 -1.6 compare
phage mixed community phage mixed community; hk phage cocktail 1 MOI; 14 member community plus Klebsiella pneumoniae -0.2 -1.6 compare
phage monoculture BHIS_CaCl2 with hk phage cocktail 1 MOI -0.2 -1.8 compare
mixed community no phage control BHIS_CaCl2 no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, standard diet, mouse 1) -0.2 -1.5 compare
phage mixed community phage mixed community; hk phage cocktail 1 MOI; 14 member community -0.2 -1.6 compare
phage mixed community phage mixed community; hk phage cocktail 1 MOI; stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 2) -0.2 -1.4 compare
mixed community no phage control BHIS_CaCl2 no phage control with 14 member community plus Klebsiella pneumoniae -0.2 -1.4 compare
mixed community no phage control BHIS_CaCl2 no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 1) -0.2 -1.4 compare
mixed community no phage control BHIS_CaCl2 no phage control with 14 member community -0.2 -1.3 compare
mixed community no phage control BHIS_CaCl2 no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, standard diet, mouse 2) -0.2 -1.1 compare
mixed community no phage control BHIS_CaCl2 no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, standard diet, mouse 1) -0.1 -1.0 compare
mixed community no phage control BHIS_CaCl2 no phage control with 14 member community -0.1 -1.0 compare
phage mixed community phage mixed community; hk phage cocktail 1 MOI; stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 1) -0.1 -0.8 compare
mixed community no phage control BHIS_CaCl2 no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 2) +0.2 +1.1 compare
mixed community no phage control BHIS no phage control with 14 member community plus Klebsiella pneumoniae +0.2 +1.1 compare
mixed community no phage control BHIS no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, standard diet, mouse 2) +0.2 +1.4 compare