Fitness data for EFB2_00138 in Escherichia fergusonii Becca

Bifunctional (p)ppGpp synthase/hydrolase SpoT
SEED: GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
KEGG: guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.3)


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group condition fitness t score  
phage mixed community phage mixed community; hk phage cocktail 1 MOI; stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 2) -1.1 -3.4 compare
mixed community no phage control BHIS no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 2) -0.9 -2.5 compare
phage monoculture BHIS_CaCl2 with hk phage cocktail 1 MOI -0.7 -2.6 compare
phage mixed community phage mixed community; hk phage cocktail 1 MOI; stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 2) -0.7 -2.1 compare
mixed community no phage control BHIS no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, standard diet, mouse 2) -0.6 -1.7 compare
mixed community no phage control BHIS_CaCl2 no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 2) -0.5 -1.7 compare
no phage control BHIS_CaCl2 no phage control -0.5 -1.3 compare
mixed community no phage control BHIS no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, standard diet, mouse 2) -0.4 -1.4 compare
mixed community no phage control BHIS_CaCl2 no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 1) -0.4 -1.6 compare
no phage control BHIS_CaCl2 no phage control -0.4 -1.5 compare
mixed community no phage control BHIS no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 1) -0.4 -1.4 compare
phage mixed community phage mixed community; hk phage cocktail 1 MOI; 14 member community -0.4 -1.4 compare
mixed community no phage control BHIS no phage control with 14 member community -0.4 -1.4 compare
mixed community no phage control BHIS_CaCl2 no phage control with 14 member community plus Klebsiella pneumoniae -0.4 -1.2 compare
mixed community no phage control BHIS no phage control with 14 member community -0.4 -1.3 compare
mixed community no phage control BHIS no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 1) -0.4 -1.1 compare
phage mixed community phage mixed community; hk phage cocktail 1 MOI; stool-derived community from humanized mice (condition: pre-antibiotic, standard diet, mouse 2) -0.3 -1.2 compare
mixed community no phage control BHIS_CaCl2 no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 1) -0.3 -1.1 compare
no phage control BHIS no phage control +0.3 +1.4 compare
mixed community no phage control BHIS_CaCl2 no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, standard diet, mouse 2) +0.4 +1.4 compare