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Protein
Homologs
Fitness for 5 genes in
Escherichia coli ECRC101
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Top 26 experiments (either direction), sorted by average fitness
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500 nt
acrR and acrA are separated by 148 nucleotides
acrA and adeB overlap by 1 nucleotides
adeB and tolC are separated by 22 nucleotides
tolC and araJ are separated by 8 nucleotides
MCAODC_15765: acrR - TetR family transcriptional regulator, at 42,204 to 42,770
acrR
MCAODC_15770: acrA - efflux transporter periplasmic adaptor subunit, at 42,919 to 44,040
acrA
MCAODC_15775: adeB - hydrophobe/amphiphile efflux-1 family RND transporter, at 44,040 to 47,129
adeB
MCAODC_15780: tolC - multidrug transporter, at 47,152 to 48,525
tolC
MCAODC_15785: araJ - Bcr/CflA family drug resistance efflux transporter, at 48,534 to 49,697
araJ
Group
Condition
MCAODC
_15765
MCAODC
_15770
MCAODC
_15775
MCAODC
_15780
MCAODC
_15785
acrR
acrA
adeB
tolC
araJ
no phage control
Control_ECRC101_WM
-0.4
-0.6
+0.4
-0.3
-0.4
phage
Bas09
-0.6
+0.3
-0.2
-0.2
-0.4
phage
EV240
-0.5
+0.2
-0.1
-0.2
-0.0
phage
Bas09
-0.5
+0.3
-0.0
+0.1
-0.1
phage
WM_RB68
-0.4
-0.1
+0.3
+0.0
+0.1
carbon source
Sodium-DL-Lactate
-0.3
-0.4
+0.1
+0.2
+0.3
phage
WM_Bas41
-0.0
-0.2
+0.2
-0.2
+0.1
phage
WM_EV240
-0.3
-0.0
+0.5
+0.1
-0.3
phage
EV240
-0.1
+0.5
-0.2
+0.1
-0.4
phage
Bas14
-0.5
+0.6
+0.1
+0.4
-0.5
carbon source
Casamino-acids
+0.2
-0.4
+0.1
-0.0
+0.2
phage
WM_TP9
-0.1
-0.1
-0.0
-0.0
+0.4
phage
WM_EV240
-0.2
+0.1
-0.0
+0.2
+0.2
phage
Bas14
-0.0
+0.4
+0.3
-0.0
-0.5
carbon source
D-Glucose
-0.0
-0.2
+0.2
+0.1
+0.1
carbon source
L-Arabinose
+0.6
-0.1
-0.1
-0.4
+0.4
carbon source
Casamino-acids
+0.0
+0.1
+0.1
+0.3
-0.0
carbon source
L-Arabinose
+0.3
+0.1
+0.0
+0.3
-0.2
no phage control
Control_ECRC101_WM
+0.1
+0.2
+0.3
+0.0
-0.1
phage
WM_TP9
-0.1
+0.3
+0.0
+0.1
+0.2
phage
WM_Bas09
-0.1
-0.0
+0.2
+0.4
+0.3
phage
WM_Bas14
-0.1
+0.3
+0.2
-0.2
+0.4
carbon source
Sodium-DL-Lactate
+0.0
-0.0
+0.1
+0.1
+0.5
phage
WM_Bas09
+0.1
+0.2
+0.2
+0.1
+0.3
phage
TP9
+0.4
+0.1
-0.2
+0.4
+0.3
carbon source
D-Glucose
+0.2
-0.3
+0.2
+0.3
+0.6
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