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Cofit
Protein
Homologs
Fitness for 5 genes in
Escherichia coli ECRC101
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Top 26 experiments (either direction), sorted by average fitness
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500 nt
metE and metR are separated by 235 nucleotides
metR and bioP overlap by 113 nucleotides
bioP and yigL are separated by 75 nucleotides
yigL and pldB are separated by 7 nucleotides
MCAODC_04830: metE - 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase, at 974,527 to 976,788
metE
MCAODC_04835: metR - HTH-type transcriptional regulator MetR, at 977,024 to 977,977
metR
MCAODC_04840: bioP - biotin transporter, at 977,865 to 978,764
bioP
MCAODC_04845: yigL - sugar/pyridoxal phosphate phosphatase YigL, at 978,840 to 979,640
yigL
MCAODC_04850: pldB - lysophospholipase L2, at 979,648 to 980,670
pldB
Group
Condition
MCAODC
_04830
MCAODC
_04835
MCAODC
_04840
MCAODC
_04845
MCAODC
_04850
metE
metR
bioP
yigL
pldB
carbon source
L-Arabinose
-3.7
-4.7
+0.0
+0.0
-0.1
carbon source
Sodium-DL-Lactate
-4.0
-4.1
+0.0
+0.1
+0.2
carbon source
Sodium-DL-Lactate
-4.2
-3.9
+0.2
+0.2
+0.1
carbon source
D-Glucose
-3.9
-3.7
+0.1
-0.0
+0.0
carbon source
D-Glucose
-3.2
-3.2
+0.1
-0.2
+0.0
carbon source
L-Arabinose
-3.4
-2.8
+0.1
-0.1
+0.0
no phage control
Control_ECRC101_WM
-0.2
-0.5
-0.1
-0.0
+0.1
phage
WM_TP9
-0.1
-0.3
-0.2
+0.0
-0.0
phage
WM_EV240
+0.0
-0.1
-0.3
-0.1
-0.1
phage
WM_TP9
-0.1
-0.3
-0.1
+0.1
-0.0
phage
Bas09
-0.1
-0.1
-0.0
-0.1
-0.0
phage
WM_Bas09
-0.0
-0.3
-0.0
+0.1
+0.0
no phage control
Control_ECRC101_WM
-0.0
-0.3
+0.1
+0.1
-0.1
carbon source
Casamino-acids
-0.1
-0.2
-0.1
+0.1
+0.1
phage
WM_Bas14
+0.1
-0.2
-0.0
-0.1
+0.1
phage
WM_RB68
+0.1
-0.1
-0.0
-0.1
+0.0
phage
TP9
+0.0
-0.1
-0.0
-0.2
+0.1
phage
Bas14
+0.1
+0.2
-0.3
+0.0
-0.1
phage
WM_EV240
+0.1
-0.0
+0.0
+0.1
-0.2
phage
WM_Bas09
+0.0
-0.3
-0.0
+0.2
+0.0
phage
Bas09
+0.1
-0.1
+0.0
+0.0
-0.1
phage
EV240
-0.0
-0.0
+0.0
+0.0
-0.0
phage
Bas14
+0.1
+0.1
+0.1
+0.1
-0.2
phage
WM_Bas41
+0.1
+0.1
+0.0
-0.0
+0.1
carbon source
Casamino-acids
+0.0
+0.2
-0.0
-0.1
+0.2
phage
EV240
+0.0
+0.2
+0.2
-0.1
+0.1
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