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Protein
Homologs
Fitness for 5 genes in
Escherichia coli ECRC98
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500 nt
wcaA and wzy overlap by 4 nucleotides
wzy and wcaA overlap by 32 nucleotides
wcaA and wzx overlap by 14 nucleotides
wzx and rfbE are separated by 2 nucleotides
JDDGAC_28520: wcaA - glycosyl transferase, at 5,471,962 to 5,472,744
wcaA
JDDGAC_28525: wzy - O157 family O-antigen polymerase, at 5,472,741 to 5,473,925
wzy
JDDGAC_28530: wcaA - glycosyl transferase, at 5,473,894 to 5,474,640
wcaA
JDDGAC_28535: wzx - O157 family O-antigen flippase, at 5,474,627 to 5,476,018
wzx
JDDGAC_28540: rfbE - GDP-perosamine synthase RfbE/PerA, at 5,476,021 to 5,477,115
rfbE
Group
Condition
JDDGAC
_28520
JDDGAC
_28525
JDDGAC
_28530
JDDGAC
_28535
JDDGAC
_28540
wcaA
wzy
wcaA
wzx
rfbE
phage
WM_JK32
-5.2
-7.1
N.D.
N.D.
-6.6
phage
WM_TP12
-5.2
-7.0
N.D.
N.D.
-6.5
phage
WM_TP12
-5.0
-6.8
N.D.
N.D.
-6.4
phage
WM_JK32
-5.0
-6.8
N.D.
N.D.
-6.3
phage
WM_JK45
-5.0
-6.7
N.D.
N.D.
-6.2
phage
WM_JK45
-4.8
-6.4
N.D.
N.D.
-5.9
phage
WM_K30
-4.2
-2.8
N.D.
N.D.
-6.5
phage
WM_EV240
-3.6
-3.2
N.D.
N.D.
-5.7
phage
WM_Bas31
-2.9
-1.7
N.D.
N.D.
-6.5
no phage control
Control_ECRC98_WM
-3.1
-1.5
N.D.
N.D.
-6.3
no phage control
Control_ECRC98_WM
-3.3
-1.1
N.D.
N.D.
-6.4
phage
WM_Bas31
-0.6
-2.1
N.D.
N.D.
-6.5
phage
WM_EV240
-2.1
-1.6
N.D.
N.D.
-5.2
phage
WM_K30
-2.3
-2.5
N.D.
N.D.
-1.4
no phage control
Control_ECRC98_WM
-2.5
+0.1
N.D.
N.D.
-3.7
no phage control
Control_ECRC98_WM
-1.1
-0.8
N.D.
N.D.
-2.8
phage
WM_Bas09
-3.0
+1.0
N.D.
N.D.
-2.6
phage
WM_Bas09
-0.8
+0.7
N.D.
N.D.
-1.7
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