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Cofit
Protein
Homologs
Fitness for 5 genes in
Escherichia coli ECOR38
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Top 29 experiments (either direction), sorted by average fitness
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500 nt
tnp-IS3 and srmB are separated by 189 nucleotides
srmB and trmN are separated by 131 nucleotides
trmN and nadB overlap by 16 nucleotides
nadB and rpoE are separated by 407 nucleotides
HEPCGN_20495: tnp-IS3 - IS3 family transposase, at 2,839,402 to 2,839,923
tnp-IS3
HEPCGN_20505: srmB - ATP-dependent RNA helicase SrmB, at 2,840,113 to 2,841,447
srmB
HEPCGN_20510: trmN - tRNA(1)(Val) (adenine(37)-N(6))-methyltransferase TrmN, at 2,841,579 to 2,842,316
trmN
HEPCGN_20515: nadB - L-aspartate oxidase, at 2,842,301 to 2,843,923
nadB
HEPCGN_20520: rpoE - RNA polymerase sigma factor RpoE, at 2,844,331 to 2,844,906
rpoE
Group
Condition
HEPCGN
_20495
HEPCGN
_20505
HEPCGN
_20510
HEPCGN
_20515
HEPCGN
_20520
tnp-IS3
srmB
trmN
nadB
rpoE
carbon source
Casamino-acids
N.D.
-1.2
+0.1
-2.1
N.D.
carbon source
Casamino-acids
N.D.
-1.2
-0.0
-1.7
N.D.
carbon source
L-Arabinose
N.D.
-0.5
-0.3
-0.7
N.D.
carbon source
D-Glucose
N.D.
-0.9
+0.1
-0.8
N.D.
carbon source
Sodium-DL-Lactate
N.D.
-1.1
+0.1
-0.6
N.D.
carbon source
Sodium-DL-Lactate
N.D.
-1.0
+0.1
-0.6
N.D.
phage
Bas38
N.D.
-1.2
-0.0
-0.1
N.D.
no phage control
Control_ECOR38
N.D.
-0.8
-0.3
-0.1
N.D.
no phage control
Control_ECOR38
N.D.
-1.2
-0.1
+0.1
N.D.
phage
Bas39
N.D.
-0.9
-0.1
-0.0
N.D.
carbon source
L-Arabinose
N.D.
-0.4
-0.0
-0.6
N.D.
phage
Bas55
N.D.
-0.5
-0.3
-0.2
N.D.
phage
Bas51
N.D.
-0.9
-0.1
+0.0
N.D.
phage
Bas38
N.D.
-0.8
+0.1
-0.2
N.D.
phage
Bas39
N.D.
-0.8
-0.0
-0.0
N.D.
phage
Bas55
N.D.
-0.5
-0.2
+0.0
N.D.
phage
RB68
N.D.
-0.7
+0.1
+0.0
N.D.
phage
K20
N.D.
-0.8
+0.1
+0.1
N.D.
phage
K20
N.D.
-0.7
+0.1
+0.0
N.D.
phage
Bas19
N.D.
-0.6
+0.1
+0.1
N.D.
phage
Bas19
N.D.
-0.2
-0.2
+0.0
N.D.
phage
Bas48
N.D.
+0.4
-0.2
-0.2
N.D.
phage
RB23
N.D.
+0.2
-0.2
+0.1
N.D.
phage
RB23
N.D.
+0.5
-0.3
+0.0
N.D.
phage
Bas48
N.D.
+0.3
+0.1
+0.1
N.D.
phage
Phi92
N.D.
+2.0
-0.4
-0.3
N.D.
phage
Phi92
N.D.
+2.1
-0.2
-0.1
N.D.
phage
TP7
N.D.
+2.3
-0.2
-0.2
N.D.
phage
TP7
N.D.
+2.2
-0.1
-0.1
N.D.
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