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Cofit
Protein
Homologs
Fitness for 5 genes in
Escherichia coli ECOR38
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500 nt
HEPCGN_12225 and argC are separated by 7 nucleotides
argC and argE are separated by 153 nucleotides
argE and ppc are separated by 301 nucleotides
ppc and ibeC are separated by 182 nucleotides
HEPCGN_12225: HEPCGN_12225 - acetylglutamate kinase, at 1,186,021 to 1,186,797
_12225
HEPCGN_12230: argC - N-acetyl-gamma-glutamyl-phosphate reductase, at 1,186,805 to 1,187,809
argC
HEPCGN_12235: argE - acetylornithine deacetylase, at 1,187,963 to 1,189,114
argE
HEPCGN_12240: ppc - phosphoenolpyruvate carboxylase, at 1,189,416 to 1,192,067
ppc
HEPCGN_12245: ibeC - phosphoethanolamine transferase CptA, at 1,192,250 to 1,193,983
ibeC
Group
Condition
HEPCGN
_12225
HEPCGN
_12230
HEPCGN
_12235
HEPCGN
_12240
HEPCGN
_12245
argC
argE
ppc
ibeC
carbon source
Sodium-DL-Lactate
-4.1
-3.3
-3.3
-4.3
-0.0
carbon source
Sodium-DL-Lactate
-3.4
-3.8
-3.6
-4.3
+0.0
carbon source
L-Arabinose
-2.8
-2.6
-3.3
-3.0
-0.1
carbon source
D-Glucose
-2.5
-2.2
-2.6
-3.3
-0.2
carbon source
L-Arabinose
-2.0
-2.7
-3.0
-2.5
-0.1
phage
TP7
-0.2
-0.2
-0.5
-0.4
-0.3
phage
Phi92
-0.3
-0.3
-0.7
+0.2
+0.0
phage
TP7
-0.2
+0.0
-0.1
-0.2
-0.2
phage
Bas19
-0.0
-0.3
+0.0
-0.2
-0.2
phage
Bas55
-0.2
-0.1
-0.0
-0.1
-0.1
phage
Bas19
-0.0
-0.4
+0.1
-0.2
-0.1
phage
RB23
+0.0
-0.1
-0.2
-0.2
-0.1
phage
Bas39
-0.4
-0.1
-0.0
+0.0
+0.1
no phage control
Control_ECOR38
-0.2
-0.0
+0.0
-0.0
-0.1
phage
RB23
+0.1
+0.0
-0.2
-0.1
-0.2
carbon source
Casamino-acids
+0.1
-0.2
-0.0
-0.1
-0.0
phage
Bas51
+0.1
-0.2
-0.1
+0.0
-0.0
phage
Bas48
+0.0
-0.1
+0.0
-0.2
+0.0
phage
K20
-0.1
-0.1
-0.0
+0.0
+0.1
no phage control
Control_ECOR38
-0.0
+0.1
-0.1
-0.1
-0.0
phage
K20
+0.0
-0.1
-0.0
-0.1
+0.0
phage
Bas48
-0.3
+0.0
+0.4
-0.2
+0.0
phage
Phi92
+0.0
+0.3
-0.3
+0.0
+0.0
phage
Bas38
-0.0
+0.0
-0.0
+0.1
-0.0
phage
RB68
+0.2
-0.0
-0.4
+0.2
+0.1
phage
Bas38
+0.1
+0.0
-0.0
-0.1
+0.0
carbon source
Casamino-acids
+0.1
+0.0
-0.1
+0.1
-0.0
phage
Bas55
+0.0
-0.1
+0.2
-0.1
+0.1
phage
Bas39
+0.1
+0.1
-0.0
+0.1
+0.1
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