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Gene
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Cofit
Protein
Homologs
Fitness for 5 genes in
Escherichia coli ECRC62
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Top 23 experiments (either direction), sorted by average fitness
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500 nt
hisA and hisH overlap by 1 nucleotides
hisH and hisB overlap by 1 nucleotides
hisB and hisC overlap by 1 nucleotides
hisC and hisD overlap by 4 nucleotides
BNILDI_14720: hisA - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase, at 2,974,208 to 2,974,945
hisA
BNILDI_14725: hisH - imidazole glycerol phosphate synthase subunit HisH, at 2,974,945 to 2,975,535
hisH
BNILDI_14730: hisB - bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB, at 2,975,535 to 2,976,602
hisB
BNILDI_14735: hisC - histidinol-phosphate transaminase, at 2,976,602 to 2,977,672
hisC
BNILDI_14740: hisD - Histidinol dehydrogenase, at 2,977,669 to 2,978,973
hisD
Group
Condition
BNILDI
_14720
BNILDI
_14725
BNILDI
_14730
BNILDI
_14735
BNILDI
_14740
hisA
hisH
hisB
hisC
hisD
carbon source
L-Arabinose
-6.1
-4.3
-7.4
-3.9
-5.0
carbon source
L-Arabinose
-6.1
-3.3
-7.4
-4.1
-4.7
carbon source
Sodium-DL-Lactate
-6.1
-4.2
-4.4
-5.1
-3.7
carbon source
D-Glucose
-6.0
-5.1
-4.3
-3.4
-4.5
carbon source
Sodium-DL-Lactate
-6.2
-3.9
-3.3
-4.2
-4.5
carbon source
D-Glucose
-6.1
-4.6
-2.8
-3.8
-4.2
no phage control
Control_ECRC62
-0.7
-1.0
+0.3
-1.2
+0.5
no phage control
Control_ECRC62
-0.5
-0.2
-0.5
+0.1
-0.1
phage
Bas61
-0.3
-0.5
-0.3
+0.0
-0.3
phage
MPec2
-0.7
+0.1
-0.3
+0.1
-0.4
carbon source
Casamino-acids
-0.1
-0.3
-0.6
-0.4
+0.3
phage
JK38
-0.5
+0.3
-0.4
+0.1
-0.6
phage
JK38
-0.4
-1.1
+0.2
+0.0
+0.1
phage
Bas05
-0.8
+0.1
-0.1
-0.3
-0.0
phage
JK36
-0.8
-0.1
-0.2
+0.2
+0.0
phage
MPec2
+0.0
-0.5
-0.4
+0.0
+0.1
phage
JK32
-0.1
-0.3
-0.0
-0.1
+0.1
carbon source
Casamino-acids
+0.0
-0.2
-0.2
-0.1
+0.0
phage
JK32
-0.3
-0.3
+0.0
-0.0
+0.3
phage
JK36
-0.2
-0.0
+0.1
+0.3
-0.1
phage
Bas68
+0.6
+0.0
-0.3
-0.1
-0.1
phage
RB68
+0.7
-0.8
+0.9
-0.1
-0.1
phage
RB68
+0.3
-0.1
+0.4
+0.5
+0.1
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BNILDI_14730
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