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Cofit
Fitness for 5 genes in
Escherichia coli BW25113
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500 nt
insC and insD-6 overlap by 43 nucleotides
insD-6 and yjgX are separated by 92 nucleotides
yjgX and yjgZ are separated by 468 nucleotides
yjgZ and insG are separated by 513 nucleotides
b4272: insC - KpLE2 phage-like element; IS2 insertion element repressor InsA (RefSeq), at 4,496,295 to 4,496,660
insC
b4273: insD-6 - KpLE2 phage-like element; IS2 insertion element transposase InsAB' (NCBI), at 4,496,618 to 4,497,523
insD-6
b4575: yjgX - no description, at 4,497,616 to 4,498,814
yjgX
b4277: yjgZ - KpLE2 phage-like element; predicted protein (NCBI), at 4,499,283 to 4,499,612
yjgZ
b4278: insG - KpLE2 phage-like element; IS4 predicted transposase (NCBI), at 4,500,126 to 4,501,454
insG
Group
Condition
b4272
b4273
b4575
b4277
b4278
insC
insD-6
yjgX
yjgZ
insG
stress
Ciprofloxacin Hydrochloride 0.0003 mM
N.D.
N.D.
-0.0
-1.0
-0.4
gfp_control
GFP_control
N.D.
N.D.
-0.4
-0.2
-0.6
stress
LB Anaerobic with Benzethonium chloride 0.00003125 mM
N.D.
N.D.
+0.1
-1.1
-0.3
mzaabcde
mzaABCDE
N.D.
N.D.
-0.2
-0.5
-0.4
phage
N4_phage 0.009375 MOI TC2
N.D.
N.D.
-0.1
-0.7
-0.1
carbon source
carbon source D-Mannose 1mM
N.D.
N.D.
-0.0
-0.9
+0.1
carbon source
carbon source D-Mannose 5mM
N.D.
N.D.
-0.1
-0.8
+0.1
micoeukaryotes
Tetrahymena sp., Mixed culture-1
N.D.
N.D.
-0.3
+0.1
-0.6
control
PBS_cage_1_mice _Feces_22 hr
N.D.
N.D.
-0.2
-0.6
+0.2
control
PBS_cage_1_mice _Feces_16 hr
N.D.
N.D.
-0.1
-0.7
+0.4
phage
HSDP3
N.D.
N.D.
+0.2
-0.6
+0.1
mzaabcde
mzaABCDE
N.D.
N.D.
-0.3
+0.3
-0.4
phage
T7_phage 0.00015625 MOI TC4
N.D.
N.D.
+0.0
-0.5
+0.5
control
PBS_cage_2_mouse_1_Cecum_40 hr
N.D.
N.D.
-0.1
+0.6
-0.2
stress
LB Anaerobic with Nitrofurantoin 0.000015625 mM
N.D.
N.D.
-0.3
+0.7
-0.0
stress
LB Aerobic with Phenazine ethosulfate 0.0000625 mM
N.D.
N.D.
+0.1
+0.7
-0.2
stress
LB Aerobic with Chlorhexidine diacetate salt 0.000000625 mM
N.D.
N.D.
-0.1
+0.8
-0.1
stress
Chloramphenicol 0.005 mg/ml
N.D.
N.D.
+0.2
+0.7
-0.1
stress
Vanillin 5 mM
N.D.
N.D.
+0.2
+0.7
-0.1
stress
Cholin acetate 75 mM
N.D.
N.D.
+0.1
+0.7
+0.0
stress
octanol 0.08 vol%
N.D.
N.D.
-0.2
+0.3
+0.8
stress
5-Hydroxymethylfurfural 20 mM
N.D.
N.D.
+0.1
+0.8
+0.0
stress
Aluminum chloride 5 mM
N.D.
N.D.
+0.2
+0.8
+0.0
stress
Cisplatin 0.1 mg/ml
N.D.
N.D.
+0.0
+1.0
-0.0
stress
Nickel (II) chloride 1 mM
N.D.
N.D.
+0.1
+0.8
+0.2
stress
Bacitracin 1 mg/ml
N.D.
N.D.
+0.2
+1.1
+0.1
phage
RB68
N.D.
N.D.
+0.4
+0.5
+0.6
phage
Ste41
N.D.
N.D.
+0.6
+0.6
+0.5
phage
RB68
N.D.
N.D.
+0.5
+0.5
+0.7
phage
Ste41
N.D.
N.D.
+0.6
+0.8
+0.8
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