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Cofit
Fitness for 5 genes in
Escherichia coli BW25113
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
yjiR and yjiS are separated by 176 nucleotides
yjiS and yjiT are separated by 498 nucleotides
yjiT and yjiV are separated by 2 nucleotides
yjiV and mcrC are separated by 56 nucleotides
b4340: yjiR - fused predicted DNA-binding transcriptional regulator/predicted aminotransferase (NCBI), at 4,568,185 to 4,569,597
yjiR
b4341: yjiS - hypothetical protein (NCBI), at 4,569,774 to 4,569,938
yjiS
b4342: yjiT - orf, hypothetical protein (VIMSS), at 4,570,437 to 4,571,939
yjiT
b4486: yjiV - conserved protein (pseudogene) (RefSeq), at 4,571,942 to 4,574,878
yjiV
b4345: mcrC - 5-methylcytosine-specific restriction enzyme McrBC, subunit McrC (NCBI), at 4,574,935 to 4,575,981
mcrC
Group
Condition
b4340
b4341
b4342
b4486
b4345
yjiR
yjiS
yjiT
yjiV
mcrC
M9 Glucose 2%, 20 mM NO3- anaerobic
+0.0
-0.6
-0.4
+0.0
-1.5
M9 Acetate 0.5% aerobic
+0.0
-0.8
-0.5
+0.1
-1.3
M9 Glucose 2% aerobic
-0.0
-0.6
-0.4
+0.0
-1.3
carbon source
carbon source D-Glucose 1mM
-0.2
-1.0
+0.0
-0.2
-1.0
motility
outer cut, LB soft agar motility assay
+0.1
-1.1
-0.3
+0.1
-1.0
M9 Acetate 0.5% aerobic
+0.1
-1.2
-0.5
+0.2
-0.7
phage
Phage_N4_cage_3_mouse_3_Cecum_40 hr
-0.1
-0.7
+0.1
+0.1
-1.3
motility
inner cut, LB soft agar motility assay
+0.3
-0.2
-0.2
+0.0
-1.7
carbon source
carbon source D-Glucose 0.25mM
-0.5
-2.0
-0.0
-0.0
+0.9
phage
Phage_N4_cage_3_mouse_1_Cecum_40 hr
-0.1
+0.3
+0.3
+0.0
-1.7
carbon source
D-Alanine (C)
-0.5
-1.0
-0.5
+0.1
+0.8
control
PBS_cage_2_mice _Feces_22 hr
-0.2
+0.4
+0.2
+0.1
-1.4
mixed community control; abiotic network
mixed community control; abiotic network
+0.0
-1.6
+0.3
+0.0
+0.6
phage
Ste41
-0.3
-1.7
+0.1
+0.1
+1.6
no phage control
CTR
-0.3
-0.7
+0.7
-0.1
+1.2
carbon source
Succinic Acid (C)
-0.1
-0.7
+0.3
+0.0
+1.3
phage
T7_phage 0.0015625 MOI TC2
-0.6
+0.2
+0.4
-0.5
+1.6
stress
Ciprofloxacin Hydrochloride 0.000156 mM
+0.2
-0.5
+0.1
-0.1
+1.6
carbon source
Inosine (C)
-0.4
-0.4
-0.2
+0.3
+2.0
phage
Papa dilution 10-1 cacl2 maltose
+0.1
-0.2
-0.0
-0.3
+2.3
no phage control
NophageCTRA12
-0.0
-0.2
+0.1
-0.1
+2.4
phage
N4_phage 0.09375 MOI TC1
-0.0
+0.0
+0.1
-0.1
+2.2
carbon source
L-Proline (C)
-0.2
-0.2
-0.0
+0.4
+2.3
no phage control
NophageCTRB12
+0.2
+1.2
-0.0
+0.2
+0.8
carbon source
acetate (C)
-0.1
-0.2
+0.3
+0.2
+2.5
phage
Phage_N4_cage_3_mouse_4_Cecum_40 hr
+0.3
-0.2
+0.3
+0.4
+2.1
phage
N4_phage 0.009375 MOI TC2
+0.1
+0.3
+0.1
-0.0
+2.4
no phage control
CTR
+0.4
+1.1
-0.2
+0.5
+1.3
carbon source
acetate (C)
+0.1
+0.2
+0.1
+0.1
+2.5
mixed community control
mixed community control
-0.0
-1.1
+0.0
-0.3
+5.9
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