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Cofit
Protein
Homologs
Fitness for 5 genes in
Escherichia coli BW25113
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500 nt
aroK and hofQ are separated by 400 nucleotides
hofQ and yrfA overlap by 89 nucleotides
yrfA and yrfB overlap by 11 nucleotides
yrfB and yrfC overlap by 17 nucleotides
b3390: aroK - shikimate kinase I (NCBI), at 3,516,565 to 3,517,086
aroK
b3391: hofQ - predicted fimbrial transporter (NCBI), at 3,517,487 to 3,518,725
hofQ
b3392: yrfA - orf, hypothetical protein (VIMSS), at 3,518,637 to 3,519,041
yrfA
b3393: yrfB - hypothetical protein (NCBI), at 3,519,031 to 3,519,471
yrfB
b3394: yrfC - predicted fimbrial assembly protein (NCBI), at 3,519,455 to 3,519,994
yrfC
Group
Condition
b3390
b3391
b3392
b3393
b3394
aroK
hofQ
yrfA
yrfB
yrfC
control
PBS_cage_1_mouse_1_Cecum_40 hr
-6.9
-0.4
-0.3
-0.5
+0.2
stress
LB Anaerobic with Benzethonium chloride 0.00003125 mM
-1.6
-2.1
-1.5
-1.7
-0.9
carbon source
Ying_AminoAcid20 rep A; time point 3
-6.6
+0.1
+0.1
+0.1
-0.2
carbon source
Ying_OrganicAcid7 rep B; time point 2
-6.5
+0.1
+0.1
-0.0
-0.1
carbon source
Ying_Nucleobase14 rep C; time point 3
-6.3
+0.1
+0.1
+0.1
-0.2
carbon source
Ying_sugar7 rep C; time point 2
-6.5
+0.2
+0.2
-0.0
+0.0
carbon source
Ying_OrganicAcid7 rep C; time point 2
-6.5
+0.1
+0.1
+0.1
+0.2
carbon source
Ying_OrganicAcid7 rep A; time point 3
-6.4
+0.1
+0.2
+0.2
-0.1
carbon source
carbon source D-Mannose 1mM
-5.4
+0.1
-0.1
-0.7
+0.2
carbon source
Ying_OrganicAcid7 rep C; time point 3
-6.3
+0.1
+0.1
+0.2
+0.3
carbon source
Ying_sugar7 rep A; time point 3
-6.3
+0.3
+0.4
+0.2
-0.1
carbon source
Ying_sugar7 rep B; time point 3
-6.4
+0.4
+0.3
+0.3
+0.1
carbon source
Ying_sugar7 rep C; time point 3
-6.3
+0.3
+0.2
+0.4
+0.3
TN_15CS_warm37C_5dbl_rep3
-5.7
+0.2
+0.2
+0.2
+0.1
carbon source
carbon source D-Glucose 0.5mM
-5.7
+0.3
+0.3
+0.2
+0.1
carbon source
carbon source D-Glucose 0.25mM
-5.3
+0.2
+0.3
+0.4
-0.4
TN_15CS_warm37C_5dbl_rep1
-5.7
+0.2
+0.3
+0.4
+0.1
TN_15CS_15C_10dbl_rep2
-5.5
+0.2
+0.2
+0.4
+0.1
carbon source
carbon source D-Mannose 20mM
-5.7
+0.2
+0.4
+0.2
+0.3
stress
LB Aerobic with Irgasan 0.0000003125 mM
+5.7
-1.7
-1.7
-0.1
-0.7
phage
T7_phage 0.00015625 MOI TC4
+4.5
-0.4
-0.3
-0.6
-0.7
stress
Trimethoprim 0.00125 mM
+5.6
-1.0
-0.9
-0.5
-0.2
stress
Nickel (II) chloride 1.5 mM
+4.9
-0.7
-0.3
-0.2
-0.2
stress
Nickel (II) chloride 1.5 mM
+5.0
-0.7
-0.3
-0.1
-0.4
phage
phage
+5.2
-0.4
-0.3
-0.6
-0.3
stress
LB Aerobic with Novobiocin 0.0000625 mM
+5.2
-0.8
-0.5
+0.1
-0.2
stress
Cephalothin 0.01 mg/ml
-2.1
+2.6
+2.2
+0.6
+0.5
stress
Trimethoprim 0.0025 mM
+6.3
-1.0
-0.6
-0.6
-0.0
stress
Trimethoprim 0.005 mM
+6.1
-0.1
-0.3
-0.5
-0.2
phage
T7_phage 0.0015625 MOI TC2
+9.8
-0.0
-1.0
+0.2
+0.5
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