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Cofit
Protein
Homologs
Fitness for 5 genes in
Escherichia coli BW25113
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500 nt
yhbP and yhbQ are separated by 50 nucleotides
yhbQ and yhbS overlap by 14 nucleotides
yhbS and yhbT overlap by 7 nucleotides
yhbT and yhbU are separated by 208 nucleotides
b3154: yhbP - hypothetical protein (NCBI), at 3,297,494 to 3,297,937
yhbP
b3155: yhbQ - hypothetical protein (NCBI), at 3,297,988 to 3,298,290
yhbQ
b3156: yhbS - predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI), at 3,298,277 to 3,298,780
yhbS
b3157: yhbT - predicted lipid carrier protein (NCBI), at 3,298,774 to 3,299,298
yhbT
b3158: yhbU - predicted peptidase (collagenase-like) (NCBI), at 3,299,507 to 3,300,502
yhbU
Group
Condition
b3154
b3155
b3156
b3157
b3158
yhbP
yhbQ
yhbS
yhbT
yhbU
stress
Benzalkonium Chloride 0.004 mg/ml
-1.6
-0.7
-0.4
-1.2
-0.0
stress
Cisplatin 0.1 mg/ml
-0.4
-1.1
-1.0
-1.2
+0.2
stress
LB Anaerobic with Cephalothin 0.0000078125 mM
+0.6
-0.3
-0.9
-0.9
-1.5
stress
LB Anaerobic with Cephalothin 0.0000078125 mM
+0.4
-0.5
-0.8
-1.3
-0.5
stress
LB Anaerobic with Zinc Pyrithione 0.0000025 mM
-0.2
-0.6
+0.1
-0.8
-0.9
lb
LB Time8hr
-0.2
-0.5
+0.1
-0.8
-0.9
plasmid transformation
vcDART vector transformation; liquid outgrowth assay
-0.5
-1.2
+0.1
-0.4
-0.2
stress
Cephalothin 0.01 mg/ml
+0.9
-0.6
-0.7
-1.1
-0.4
lb
LB regrowth after 48hrs
+0.1
-0.1
+0.3
-0.8
-1.1
phage
Ste41
+0.7
-1.2
-0.1
-1.0
+0.3
predation
6 hr rep1_HD100_10fold_dilution_grewON
-0.1
-1.6
-0.4
+0.7
+0.6
plasmid transformation
vcDART vector transformation; liquid outgrowth assay
+0.5
+0.1
+0.4
-1.7
+0.1
carbon source
Acetate (C)
-0.2
-0.8
-0.7
+1.0
+0.1
carbon source
Glycolic Acid (C)
-0.1
-0.3
-1.1
+1.1
+0.1
carbon source
Glycolic Acid (C)
-0.2
+0.0
-1.3
+1.1
+0.1
carbon source
Acetate (C)
-0.3
-0.4
-1.0
+1.3
+0.4
stress
LB Anaerobic with Cefoxitin 0.000003125 mM
+0.1
-0.6
-0.7
+0.8
+0.6
control
PBS_cage_2_mouse_2_Cecum_40 hr
+0.1
-0.6
+0.5
+1.0
-0.4
control
PBS_cage_2_mice _Feces_40 hr
-0.3
-0.3
+0.6
+0.9
-0.3
micoeukaryotes
Tetrahymena sp., Mixed culture-1
+0.7
-0.8
-0.1
+0.7
+0.2
stress
Bacitracin 1 mg/ml
+1.4
-0.4
+0.2
+0.5
-0.1
stress
Nickel (II) chloride 1.5 mM
+0.0
+0.0
-0.7
+1.7
+0.5
stress
Nickel (II) chloride 1.5 mM
-0.0
+0.1
-0.6
+1.5
+0.5
carbon source
succinate (C)
-0.2
-0.2
+0.4
+1.6
+0.1
stress
LB Anaerobic with Vancomycin Hydrochloride from Streptomyces orientalis 0.00003125 mM
+0.6
-0.6
+0.5
+0.9
+0.4
stress
Nickel (II) chloride 1 mM
-0.3
+0.2
-0.6
+2.0
+0.8
stress
Nickel (II) chloride 1.5 mM
+0.3
-0.3
-0.8
+2.0
+0.8
stress
LB Anaerobic with Ampicillin 0.00000195313 mM
+1.2
+0.8
-0.1
+0.0
+0.3
carbon source
a-Ketoglutaric (C)
+0.1
+0.2
+0.3
+2.0
+0.1
stress
LB Anaerobic with Benzethonium chloride 0.00003125 mM
+3.0
-0.3
+0.6
+1.8
+1.3
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