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Cofit
Protein
Homologs
Fitness for 5 genes in
Escherichia coli BW25113
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500 nt
yqgC and metK are separated by 303 nucleotides
metK and galP are separated by 423 nucleotides
galP and sprT are separated by 76 nucleotides
sprT and endA are separated by 94 nucleotides
b2940: yqgC - hypothetical protein (NCBI), at 3,084,209 to 3,084,424
yqgC
b2942: metK - S-adenosylmethionine synthetase (NCBI), at 3,084,728 to 3,085,882
metK
b2943: galP - galactose:H+ symporter (galP)
(from data)
, at 3,086,306 to 3,087,700
galP
b2944: sprT - hypothetical protein (NCBI), at 3,087,777 to 3,088,274
sprT
b2945: endA - DNA-specific endonuclease I (NCBI), at 3,088,369 to 3,089,076
endA
Group
Condition
b2940
b2942
b2943
b2944
b2945
yqgC
metK
galP
sprT
endA
gfp_control
GFP_control
+1.0
N.D.
-0.0
-0.1
-9.7
drt_type_3
DRT_type_3
+0.9
N.D.
-0.0
+0.2
-9.8
sir2-hera
SIR2-HerA
+0.6
N.D.
-0.0
+0.1
-9.1
mzaabcde
mzaABCDE
+0.8
N.D.
-0.0
+0.2
-9.5
drt_type_3
DRT_type_3
+0.9
N.D.
+0.1
+0.3
-9.6
gfp_control
GFP_control
+1.0
N.D.
+0.0
+0.2
-9.4
gfp_control
GFP_control
+1.3
N.D.
+0.0
+0.1
-9.4
retron_ec_48_control
retron_Ec_48_control
+0.8
N.D.
+0.1
+0.5
-9.1
ppi
ppI
+0.6
N.D.
-0.0
+0.1
-8.2
mzaabcde
mzaABCDE
+0.6
N.D.
-0.0
+0.2
-8.3
drt_type_3
DRT_type_3
+0.7
N.D.
-0.1
+0.1
-8.2
retron_ec_48_control
retron_Ec_48_control
+0.6
N.D.
+0.0
+0.4
-8.0
retron_ec_48_control
retron_Ec_48_control
+0.9
N.D.
-0.0
+0.3
-8.0
sir2-hera
SIR2-HerA
+1.0
N.D.
-0.0
+0.2
-8.0
sir2-hera
SIR2-HerA
+0.8
N.D.
-0.0
+0.2
-7.8
ppi
ppI
+0.5
N.D.
-0.1
+0.2
-6.9
ppi
ppI
+1.1
N.D.
-0.0
+0.2
-6.7
mzaabcde
mzaABCDE
+1.1
N.D.
+0.1
+0.1
-6.7
carbon source
D-Galactose (C)
-0.1
N.D.
-3.2
-0.3
+0.1
carbon source
D-Galactose (C)
-0.1
N.D.
-2.6
-0.2
-0.2
carbon source
carbon source D-Glucose 0.25mM
-1.7
N.D.
-0.1
-0.5
-0.5
plasmid transformation
vcDART vector transformation; liquid outgrowth assay
-1.1
N.D.
-0.2
+0.1
-1.6
predation
6 hr rep1_HD100_10fold_dilution_grewON
-2.5
N.D.
+0.1
+0.1
+0.1
stress
Cisplatin 0.1 mg/ml
+0.2
N.D.
-0.1
+0.0
-2.1
stress
LB Aerobic with Nitrofurantoin 0.00003125 mM
-1.4
N.D.
+0.4
+0.3
-0.5
micoeukaryotes
Tetrahymena sp., Mixed culture-1
-1.0
N.D.
-0.0
-0.8
+0.7
stress
Cisplatin 0.1 mg/ml
-0.1
N.D.
+0.4
+0.5
-1.7
stress
LB Anaerobic with Nitrofurantoin 0.00003125 mM
-1.6
N.D.
+0.1
+0.4
+0.3
nitrogen source
L-Arginine (N)
-0.5
N.D.
+0.0
+1.8
-0.2
stress
Spectinomycin 0.0125 mg/ml
+1.9
N.D.
+0.1
-0.1
-0.7
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