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Cofit
Protein
Homologs
Fitness for 5 genes in
Escherichia coli BW25113
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500 nt
yebT and yebU are separated by 79 nucleotides
yebU and yebV are separated by 117 nucleotides
yebV and yebW are separated by 104 nucleotides
yebW and pphA are separated by 0 nucleotides
b1834: yebT - orf, hypothetical protein (VIMSS), at 1,915,534 to 1,918,167
yebT
b1835: yebU - putative nucleolar proteins (VIMSS), at 1,918,247 to 1,919,686
yebU
b1836: yebV - orf, hypothetical protein (VIMSS), at 1,919,804 to 1,920,040
yebV
b1837: yebW - orf, hypothetical protein (VIMSS), at 1,920,145 to 1,920,336
yebW
b1838: pphA - protein phosphatase 1 modulates phosphoproteins, signals protein misfolding (VIMSS), at 1,920,337 to 1,920,993
pphA
Group
Condition
b1834
b1835
b1836
b1837
b1838
yebT
yebU
yebV
yebW
pphA
carbon source
acetate (C)
-0.0
+0.4
-2.4
-2.9
+0.3
carbon source
acetate (C)
-0.2
+0.2
-2.2
-2.0
+0.3
carbon source
carbon source D-Glucose 0.25mM
+0.0
-1.0
-1.7
-0.3
-0.7
carbon source
carbon source D-Mannose 5mM
+0.0
-0.1
-0.4
-1.9
-1.1
phage
Δdbn_10
-0.0
-0.4
-1.1
-1.3
-0.6
stress
octanol 0.08 vol%
-2.8
+0.8
-0.8
-1.0
+0.4
carbon source
Ying_Others16 rep B; time point 2
-0.1
+0.6
-1.1
-1.7
+0.0
carbon source
carbon source D-Mannose 1mM
+0.2
-0.1
-1.5
-1.4
+0.7
carbon source
succinate (C)
+0.1
+0.3
-0.8
-1.9
+0.4
carbon source
D-Lactate (C)
-0.1
+0.3
-1.5
-1.0
+0.4
carbon source
L-Malic (C)
-0.3
+0.6
-1.1
-1.4
+0.6
nophagecontrol
R1_N4_T1_phage0
-0.2
+0.5
-1.9
+1.0
-0.8
control
PBS_cage_1_mouse_1_Cecum_40 hr
+0.5
+0.3
+0.5
-1.9
-0.6
stress
LB Aerobic with Chlorhexidine diacetate salt 0.000000625 mM
-1.7
+0.8
-0.7
+0.5
+0.1
carbon source
carbon source D-Glucose 0.25mM
-0.0
+0.8
-2.0
-0.6
+0.8
predation
6 hr rep2_HD100_10fold_dilution_grewON
-0.3
+0.9
-0.1
-1.8
+0.5
plasmid transformation
vcDART vector transformation; liquid outgrowth assay
-0.3
+2.6
-0.3
-2.0
-1.0
stress
Bacitracin 1 mg/ml
+1.2
-0.9
+0.6
-1.3
+0.0
stress
LB Aerobic with Ramoplanin 0.000125 mM
+1.6
-0.6
+0.1
-0.4
-0.7
stress
LB Anaerobic with Benzethonium chloride 0.00003125 mM
-0.8
+0.6
+0.9
-1.0
+0.4
stress
LB Aerobic with Chlorhexidine diacetate salt 0.000000625 mM
-1.5
+0.3
+0.3
+0.8
+0.5
phage
Ste41
-0.5
+0.2
+1.0
+0.8
-0.8
motility
inner cut, LB soft agar motility assay
-0.1
+0.5
-1.0
+2.0
+0.3
plasmid transformation
vcDART vector transformation; agar assay
-0.0
+2.4
+0.5
-0.4
-0.0
phage
Ste41
-0.8
+0.7
+2.2
+0.7
+0.5
plasmid transformation
mariner vector transformation; liquid outgrowth assay
+0.0
+3.2
+0.2
-0.2
+0.2
plasmid transformation
mariner vector transformation; liquid outgrowth assay
-0.2
+3.6
-0.2
+0.3
-0.2
plasmid transformation
mariner vector transformation; liquid outgrowth assay
+0.0
+3.7
-0.2
+0.5
-0.3
plasmid transformation
vcDART vector transformation; liquid outgrowth assay
-0.0
+4.5
+0.1
-0.1
-0.2
plasmid transformation
vcDART vector transformation; liquid outgrowth assay
+0.1
+4.7
+0.4
+0.7
+0.7
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