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Cofit
Protein
Homologs
Fitness for 5 genes in
Escherichia coli BW25113
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500 nt
pps and ydiA are separated by 332 nucleotides
ydiA and aroH are separated by 156 nucleotides
aroH and ydiE are separated by 131 nucleotides
ydiE and ydiU are separated by 3 nucleotides
b1702: pps - phosphoenolpyruvate synthase (NCBI), at 1,782,758 to 1,785,136
pps
b1703: ydiA - hypothetical protein (NCBI), at 1,785,469 to 1,786,302
ydiA
b1704: aroH - 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, tryptophan repressible (NCBI), at 1,786,459 to 1,787,505
aroH
b1705: ydiE - hypothetical protein (NCBI), at 1,787,637 to 1,787,828
ydiE
b1706: ydiU - hypothetical protein (NCBI), at 1,787,832 to 1,789,268
ydiU
Group
Condition
b1702
b1703
b1704
b1705
b1706
pps
ydiA
aroH
ydiE
ydiU
carbon source
acetate (C)
-4.9
-0.7
-0.7
N.D.
-0.2
carbon source
pyruvate (C)
-4.8
-0.5
-0.4
N.D.
-0.0
carbon source
pyruvate (C)
-4.9
-0.5
-0.1
N.D.
-0.2
carbon source
D,L-Lactate (C)
-4.7
-0.8
-0.2
N.D.
+0.2
carbon source
D-Serine (C)
-4.2
-0.2
-1.0
N.D.
+0.0
carbon source
acetate (C)
-4.0
-0.6
-0.6
N.D.
-0.1
carbon source
D,L-Lactate (C)
-4.3
-0.4
-0.4
N.D.
-0.1
carbon source
D-Serine (C)
-3.8
-0.4
-0.8
N.D.
-0.0
carbon source
Acetate (C)
-4.2
-0.6
+0.0
N.D.
-0.2
carbon source
Acetate (C)
-3.8
-0.5
-0.1
N.D.
-0.1
M9 Acetate 0.5% aerobic
-3.0
-0.9
+0.1
N.D.
-0.2
carbon source
D-Lactate (C)
-2.9
-0.4
-0.3
N.D.
+0.0
M9 Acetate 0.5% aerobic
-2.7
-0.6
+0.0
N.D.
-0.1
carbon source
D-Lactate (C)
-2.8
-0.2
-0.4
N.D.
-0.0
carbon source
casaminos (C)
-0.2
-0.1
-2.6
N.D.
-0.2
nitrogen source
D-Serine (N)
-2.8
-0.1
-0.4
N.D.
+0.1
nitrogen source
D-Serine (N)
-2.5
+0.3
-0.6
N.D.
-0.0
carbon source
Ying_OrganicAcid7 rep A; time point 3
-2.4
+0.1
-0.2
N.D.
-0.3
predation
6 hr rep1_HD100_10fold_dilution_grewON
+0.5
-1.0
-0.8
N.D.
-1.0
carbon source
Ying_OrganicAcid7 rep B; time point 3
-2.3
+0.2
-0.0
N.D.
-0.1
carbon source
casaminos (C)
-0.4
+0.0
-2.1
N.D.
+0.1
carbon source
carbon source D-Glucose 0.25mM
-0.9
-0.1
-0.5
N.D.
-0.7
carbon source
Ying_OrganicAcid7 rep C; time point 3
-2.2
+0.4
-0.2
N.D.
-0.3
carbon source
Ying_OrganicAcid7 rep B; time point 2
-2.1
-0.0
+0.1
N.D.
+0.0
carbon source
Ying_OrganicAcid7 rep C; time point 2
-1.8
+0.1
+0.0
N.D.
-0.2
carbon source
Ying_OrganicAcid7 rep A; time point 2
-1.5
+0.2
-0.3
N.D.
-0.2
stress
Trimethoprim 0.005 mM
-0.1
-1.1
-0.7
N.D.
+0.2
phage
RB68
-0.7
+0.7
+0.8
N.D.
+0.2
phage
RB68
-0.4
+0.5
+0.6
N.D.
+0.9
phage
Papa dilution 10-1 cacl2 maltose
+0.3
+0.8
+0.4
N.D.
+0.9
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