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Cofit
Fitness for 5 genes in
Escherichia coli BW25113
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500 nt
ydfE and insD are separated by 2 nucleotides
insD and intQ are separated by 13 nucleotides
intQ and rspB are separated by 187 nucleotides
rspB and rspA are separated by 11 nucleotides
b1577: ydfE - Qin prophage; predicted protein (RefSeq), at 1,648,102 to 1,648,866
ydfE
b1578: insD - Qin prophage; IS2 insertion element transposase InsAB', C-ter fragment (pseudogene) (RefSeq), at 1,648,869 to 1,649,561
insD
b1579: intQ - Qin prophage; predicted defective integrase (RefSeq), at 1,649,575 to 1,650,732
intQ
b1580: rspB - predicted oxidoreductase, Zn-dependent and NAD(P)-binding (NCBI), at 1,650,920 to 1,651,939
rspB
b1581: rspA - predicted dehydratase (NCBI), at 1,651,951 to 1,653,165
rspA
Group
Condition
b1577
b1578
b1579
b1580
b1581
ydfE
insD
intQ
rspB
rspA
carbon source
carbon source D-Glucose 0.25mM
-0.1
N.D.
-2.0
-1.5
-0.4
carbon source
carbon source D-Mannose 0.5mM
-0.5
N.D.
-2.3
-0.6
-0.2
M9 Acetate 0.5% aerobic
-0.2
N.D.
-2.5
-0.5
+0.4
M9 Glucose 2% aerobic
-0.2
N.D.
-2.1
-0.4
-0.0
M9 Glucose 2% aerobic
-0.1
N.D.
-2.1
-0.3
-0.1
carbon source
carbon source D-Glucose 0.5mM
-0.6
N.D.
-1.1
-0.0
-0.8
predation
6 hr rep1_HD100_10fold_dilution_grewON
+0.0
N.D.
-0.8
-0.2
-1.4
M9 Glucose 2%, 20 mM NO3- anaerobic
-0.2
N.D.
-2.0
-0.3
+0.1
M9 Acetate 0.5% aerobic
-0.2
N.D.
-2.3
-0.3
+0.6
nophagecontrol
R1_N4_T1_phage0
+0.0
N.D.
-0.8
-0.8
-0.6
M9 Glucose 2% anaerobic
-0.1
N.D.
-1.9
-0.2
+0.2
M9 Glucose 2% anaerobic
-0.0
N.D.
-1.6
-0.3
+0.3
phage
T7_phage 0.0015625 MOI TC2
-0.9
N.D.
+0.5
-0.3
-0.8
carbon source
carbon source D-Glucose 0.5mM
-0.2
N.D.
-1.6
+0.1
+0.4
phage
N4_phage 0.00009375 MOI TC4
-0.1
N.D.
-0.1
+0.7
-1.5
carbon source
carbon source D-Mannose 1mM
-0.1
N.D.
-1.5
+0.4
+0.3
stress
LB Anaerobic with Ramoplanin 0.0000625 mM
+0.2
N.D.
-1.0
-0.6
+0.7
phage
R2_N4_T2_phage10
+0.6
N.D.
-0.8
+0.3
-0.7
carbon source
carbon source D-Glucose 0.25mM
-0.8
N.D.
-1.0
+0.5
+0.9
stress
LB Aerobic with Spiramycin 0.000125 mM
+0.3
N.D.
-1.0
-0.4
+0.6
phage
Phage_N4_cage_3_mouse_3_Cecum_40 hr
-0.1
N.D.
-0.8
-0.4
+1.0
stress
LB Aerobic with Trimethoprim 0.00000125 mM
+0.5
N.D.
-0.6
-0.5
+0.6
control
PBS_cage_1_mouse_1_Cecum_40 hr
+0.5
N.D.
-0.7
-0.9
+1.2
stress
Ciprofloxacin Hydrochloride 0.0024 mM
+0.4
N.D.
-0.9
-0.2
+0.8
carbon source
carbon source D-Mannose 5mM
-0.1
N.D.
-0.5
-0.4
+1.2
stress
LB Anaerobic with Ampicillin 0.00000195313 mM
+0.3
N.D.
-0.2
-0.7
+1.0
stress
Trimethoprim 0.005 mM
+0.5
N.D.
+1.9
+0.4
-2.0
phage
Δdbn_10
+0.6
N.D.
+1.1
-0.3
-0.4
phage
Papa dilution 10-1 cacl2 maltose
-0.0
N.D.
+1.4
-0.4
+0.6
phage
N4_phage 0.009375 MOI TC2
+0.3
N.D.
+1.7
-0.0
+0.4
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