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Cofit
Protein
Homologs
Fitness for 5 genes in
Escherichia coli BW25113
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500 nt
ompW and yciE are separated by 59 nucleotides
yciE and yciF are separated by 45 nucleotides
yciF and yciG are separated by 85 nucleotides
yciG and trpA are separated by 380 nucleotides
b1256: ompW - outer membrane protein W (NCBI), at 1,312,044 to 1,312,682
ompW
b1257: yciE - hypothetical protein (NCBI), at 1,312,742 to 1,313,248
yciE
b1258: yciF - hypothetical protein (NCBI), at 1,313,294 to 1,313,794
yciF
b1259: yciG - orf, hypothetical protein (VIMSS), at 1,313,880 to 1,314,059
yciG
b1260: trpA - tryptophan synthase subunit alpha (NCBI), at 1,314,440 to 1,315,246
trpA
Group
Condition
b1256
b1257
b1258
b1259
b1260
ompW
yciE
yciF
yciG
trpA
carbon source
carbon source D-Glucose 0.25mM
-0.3
-1.3
-1.5
-3.3
-10.0
carbon source
carbon source D-Mannose 0.5mM
-0.0
-1.7
-1.9
-0.9
-10.5
carbon source
carbon source D-Mannose 20mM
+0.1
-1.7
-2.0
-0.7
-10.7
carbon source
carbon source D-Mannose 5mM
+0.2
-1.5
-1.0
-0.8
-10.4
carbon source
Ying_OrganicAcid7 rep B; time point 2
+0.0
-0.7
-1.6
-0.4
-10.9
carbon source
carbon source D-Glucose 0.25mM
+0.1
-1.4
-1.6
+0.2
-10.2
carbon source
carbon source D-Glucose 1mM
-0.0
-1.8
-0.3
-0.1
-10.7
carbon source
Ying_OrganicAcid7 rep A; time point 2
+0.0
-0.7
-0.5
-0.5
-11.1
carbon source
Ying_Nucleobase14 rep B; time point 2
-0.1
-0.7
-1.2
+0.2
-10.9
carbon source
carbon source D-Mannose 1mM
-0.1
-1.6
-1.8
+1.2
-10.4
carbon source
Ying_OrganicAcid7 rep C; time point 3
+0.1
-0.6
-0.2
-1.1
-10.8
carbon source
carbon source D-Glucose 1mM
-0.1
-1.6
-0.0
-0.2
-10.5
carbon source
carbon source D-Glucose 0.5mM
+0.0
-1.8
-0.3
+0.3
-10.7
M9 Glucose 2% aerobic
-0.1
-4.2
-1.6
-1.0
-5.3
carbon source
Ying_sugar7 rep A; time point 2
-0.0
-0.8
-0.6
+0.3
-11.0
carbon source
Ying_OrganicAcid7 rep B; time point 3
+0.0
-0.6
-0.5
+0.1
-11.0
carbon source
Ying_OrganicAcid7 rep A; time point 3
+0.2
-0.6
-0.5
+0.0
-10.8
carbon source
Ying_Nucleobase14 rep A; time point 2
-0.0
-0.7
+0.4
-0.2
-11.1
carbon source
Ying_Nucleobase14 rep A; time point 3
-0.1
+0.2
-0.4
-0.4
-10.8
carbon source
Ying_OrganicAcid7 rep C; time point 2
+0.1
-0.7
-1.6
-0.0
-8.9
carbon source
Ying_sugar7 rep C; time point 2
-0.1
-0.2
-0.1
+0.0
-11.0
carbon source
Ying_sugar7 rep B; time point 2
-0.0
-0.8
+0.5
+0.1
-11.0
carbon source
Ying_sugar7 rep C; time point 3
-0.0
-0.7
-0.5
+0.9
-10.8
carbon source
Glycolic Acid (C)
+0.0
-2.7
-0.2
+0.1
-8.1
carbon source
Ying_Nucleobase14 rep B; time point 3
-0.0
-0.3
+0.2
+0.0
-10.7
carbon source
Ying_sugar7 rep A; time point 3
+0.1
+0.7
-0.5
+0.1
-10.9
carbon source
Ying_sugar7 rep B; time point 3
+0.1
-0.1
+0.1
+0.6
-10.9
carbon source
a-Ketoglutaric (C)
-0.0
-2.4
-0.3
+0.4
-7.8
phage
RB68
+8.9
+1.0
+0.1
+0.4
+0.4
phage
RB68
+10.1
+1.4
+1.0
-1.5
+0.3
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