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Cofit
Protein
Homologs
Fitness for 5 genes in
Escherichia coli BW25113
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500 nt
ybjD and ybjX overlap by 4 nucleotides
ybjX and b0878 are separated by 114 nucleotides
b0878 and macB overlap by 4 nucleotides
macB and cspD are separated by 72 nucleotides
b0876: ybjD - conserved protein with nucleoside triphosphate hydrolase domain (NCBI), at 915,696 to 917,354
ybjD
b0877: ybjX - hypothetical protein (NCBI), at 917,351 to 918,343
ybjX
b0878: b0878 - putative membrane protein (VIMSS), at 918,458 to 919,573
b0878
b0879: macB - fused macrolide transporter subunits of ABC superfamily: ATP-binding component/membrane component (NCBI), at 919,570 to 921,516
macB
b0880: cspD - cold shock protein homolog (NCBI), at 921,589 to 921,813
cspD
Group
Condition
b0876
b0877
b0878
b0879
b0880
ybjD
ybjX
b0878
macB
cspD
carbon source
carbon source D-Glucose 0.25mM
+0.0
-0.2
+0.1
+0.1
-5.8
micoeukaryotes
Tetrahymena sp., Mixed culture-1
-0.2
+0.1
+0.3
-0.1
-5.5
carbon source
carbon source D-Mannose 5mM
-0.5
-0.1
-0.5
-0.2
-3.6
phage
Δdbn_10
+0.0
-0.0
+0.2
-0.3
-4.7
phage
TP4
-0.6
-0.5
-0.8
+0.0
-2.1
stress
Benzalkonium Chloride 0.004 mg/ml
-0.3
-3.3
+0.8
+0.6
-1.4
phage
RB68
-0.1
-0.6
+0.1
-0.1
-2.4
stress
LB Anaerobic with Benzethonium chloride 0.00003125 mM
-0.2
-3.8
+0.1
+0.1
+0.9
phage
RB68
-0.2
-0.7
+0.2
-0.4
-1.5
control
PBS_cage_1_mouse_1_Cecum_40 hr
+0.3
-0.5
+0.3
-0.4
-2.2
phage
Ste41
+0.7
+0.3
-1.7
-0.6
-1.2
stress
LB Aerobic with Ramoplanin 0.000125 mM
-0.0
-3.6
+1.2
+1.3
-1.1
stress
LB Aerobic with Ramoplanin 0.000125 mM
-0.1
-3.6
+1.0
+1.1
-0.5
stress
Doxycycline hyclate 0.001 mg/ml
+0.3
-2.0
+0.8
-0.0
-1.1
stress
LB Anaerobic with Cephalothin 0.0000078125 mM
-0.4
-1.8
-0.2
-0.1
+0.9
carbon source
carbon source D-Mannose 5mM
-0.2
+0.3
+0.3
-0.1
-1.7
stress
Cephalothin 0.01 mg/ml
+0.2
-1.7
+0.4
+0.1
-0.4
nophagecontrol
R1_N4_T1_phage0
+0.2
+0.3
-0.6
+0.2
-1.1
stress
LB Anaerobic with Ampicillin 0.00000195313 mM
+0.2
-0.4
+0.9
-0.2
-1.4
control
PBS_cage_2_mouse_1_Cecum_40 hr
+0.3
-0.7
+0.4
+0.2
-0.9
phage
T7_phage 0.00015625 MOI TC2
+0.1
+0.7
-0.5
+0.1
-1.0
stress
LB Anaerobic with Cephalothin 0.0000078125 mM
+0.2
-1.4
-0.1
+0.0
+1.0
stress
LB Anaerobic with Chlorhexidine diacetate salt 0.000000625 mM
-0.5
-0.7
+0.2
+0.2
+0.9
stress
Chlorite 0.4 mM
+0.4
+0.3
+0.7
-0.2
-1.0
stress
Cisplatin 0.1 mg/ml
+0.1
+0.5
-0.6
-0.6
+1.1
phage
R2_N4_T1_phage10
+0.3
-0.7
-1.0
+0.0
+2.2
motility
outer cut, LB soft agar motility assay
-0.5
+0.5
-0.2
-0.0
+1.2
stress
Bacitracin 0.5 mg/ml
+0.1
+1.2
-0.4
-0.7
+1.0
plasmid transformation
mariner vector transformation; liquid outgrowth assay
-0.3
-0.2
+0.4
+0.5
+1.1
stress
Bacitracin 1 mg/ml
+0.4
+4.3
-1.2
-2.2
+0.5
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