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Cofit
Protein
Homologs
Fitness for 5 genes in
Escherichia coli BW25113
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500 nt
ybdM and ybdN overlap by 28 nucleotides
ybdN and ybdO are separated by 146 nucleotides
ybdO and dsbG are separated by 208 nucleotides
dsbG and ahpC are separated by 371 nucleotides
b0601: ybdM - hypothetical protein (NCBI), at 633,970 to 634,599
ybdM
b0602: ybdN - hypothetical protein (NCBI), at 634,572 to 635,792
ybdN
b0603: ybdO - predicted DNA-binding transcriptional regulator (NCBI), at 635,939 to 636,841
ybdO
b0604: dsbG - thiol:disulfide interchange protein (VIMSS), at 637,050 to 637,796
dsbG
b0605: ahpC - alkyl hydroperoxide reductase, C22 subunit (NCBI), at 638,168 to 638,731
ahpC
Group
Condition
b0601
b0602
b0603
b0604
b0605
ybdM
ybdN
ybdO
dsbG
ahpC
motility
outer cut, LB soft agar motility assay
-0.3
+0.2
-3.1
-0.1
-3.8
stress
Cisplatin 0.1 mg/ml
-0.8
+0.3
-1.9
-0.2
-3.5
motility
outer cut, LB soft agar motility assay
-0.2
+0.5
-1.7
-0.1
-4.4
stress
LB Aerobic with Ramoplanin 0.000125 mM
-0.7
+0.1
+0.1
-0.2
-4.1
stress
LB Aerobic with Chlorhexidine diacetate salt 0.000000625 mM
-0.5
+0.3
-0.1
-0.3
-4.0
motility
outer cut, LB soft agar motility assay
-0.3
+0.1
-3.2
-0.0
-1.0
stress
LB Aerobic with Ramoplanin 0.000125 mM
-0.3
-0.2
-0.1
+0.2
-3.8
stress
LB Aerobic with Chlorhexidine diacetate salt 0.000000625 mM
+0.1
-0.2
+0.2
-0.2
-3.9
motility
inner cut, LB soft agar motility assay
+0.4
-0.2
-2.3
+0.2
-2.2
stress
LB Aerobic with Zinc Pyrithione 0.0000025 mM
-0.0
+0.0
-0.3
+0.3
-3.6
stress
LB Aerobic with Zinc Pyrithione 0.0000025 mM
-0.2
+0.0
+0.2
+0.2
-3.6
motility
inner cut, LB soft agar motility assay
-0.0
+0.1
-2.8
+0.3
-1.1
stress
Aluminum chloride 5 mM
+0.2
-0.1
-2.0
-0.5
-1.1
control
PBS_cage_2_mouse_1_Cecum_40 hr
-0.0
-0.2
+1.0
-1.2
-3.0
M9 Glucose 2% aerobic
+0.1
+0.1
-2.9
-0.1
-0.6
motility
inner cut, LB soft agar motility assay
+0.2
-0.8
-2.1
+0.5
-0.9
stress
Carbenicillin 0.008 mg/ml
+0.0
+0.1
-1.4
+0.2
-2.2
stress
Benzalkonium Chloride 0.004 mg/ml
+0.1
+0.2
-2.7
+0.7
-1.5
stress
LB Anaerobic with Chlorhexidine diacetate salt 0.000000625 mM
-0.2
-0.3
-0.1
+0.4
-2.8
predation
6 hr rep2_HD100_10fold_dilution_grewON
+0.2
+0.1
-0.0
+0.1
-3.3
stress
LB Aerobic with Doxycycline hyclate 0.00000625 mM
-0.0
+0.1
+0.4
+0.1
-3.2
stress
LB Aerobic with 2-Mercaptopyridine N-oxide 0.0000078125 mM
-0.1
+0.0
+0.7
+0.1
-3.2
stress
LB Anaerobic with Cephalothin 0.0000078125 mM
+0.2
+0.4
+0.2
+0.2
-3.3
control
PBS_cage_1_mouse_1_Cecum_40 hr
-0.2
+0.7
+1.1
-0.5
-2.4
phage
RB68
+0.2
+0.2
+1.0
-0.5
-2.2
phage
Δdbn_10
-0.2
-0.0
+1.4
+0.4
-2.9
carbon source
Glycolic Acid (C)
-0.3
+0.2
-1.8
+0.1
+1.6
phage
Papa dilution 10-1 cacl2 maltose
-0.3
-0.4
+3.2
-0.3
-0.4
stress
LB Aerobic with Phenazine ethosulfate 0.0000625 mM
-0.0
+0.1
+0.6
+0.1
+3.4
stress
LB Aerobic with Phenazine ethosulfate 0.0000625 mM
-0.3
-0.3
+1.3
-0.1
+5.0
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