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Cofit
Protein
Homologs
Fitness for 5 genes in
Escherichia coli BW25113
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500 nt
yaiV and ampH are separated by 0 nucleotides
ampH and sbmA are separated by 351 nucleotides
sbmA and yaiW are separated by 12 nucleotides
yaiW and yaiY are separated by 58 nucleotides
b0375: yaiV - predicted DNA-binding transcriptional regulator (RefSeq), at 393,730 to 394,353
yaiV
b0376: ampH - beta-lactamase/D-alanine carboxypeptidase (NCBI), at 394,354 to 395,511
ampH
b0377: sbmA - predicted transporter (NCBI), at 395,863 to 397,083
sbmA
b0378: yaiW - predicted DNA-binding transcriptional regulator (NCBI), at 397,096 to 398,190
yaiW
b0379: yaiY - predicted inner membrane protein (NCBI), at 398,249 to 398,557
yaiY
Group
Condition
b0375
b0376
b0377
b0378
b0379
yaiV
ampH
sbmA
yaiW
yaiY
stress
2,4-Dinitrophenol 2 mM
+0.0
-0.0
-3.2
+0.2
-0.2
carbon source
carbon source D-Mannose 5mM
-0.6
-0.4
-0.2
-0.5
-1.4
phage
T7_phage 0.00015625 MOI TC4
+0.4
-0.2
-0.3
-0.4
-2.2
stress
2,4-Dinitrophenol 2 mM
+0.0
+0.1
-2.8
+0.0
-0.0
stress
LB Aerobic with Ramoplanin 0.000125 mM
-0.8
-1.1
+0.4
+0.1
-0.1
control
PBS_cage_1_mouse_1_Cecum_40 hr
-1.3
+0.2
+0.0
-0.2
+0.0
mzaabcde
mzaABCDE
-0.6
+0.2
+0.1
+0.0
-0.9
attachment_assay_attached_sample
Time0_Wash=None; Attachment_time=2hrs; Attachment_surface=PDMS; Sample_type=attached; Outgrowth=LB
+0.5
-0.4
-0.3
-0.5
-0.3
phage
T7_phage 0.0015625 MOI TC1
+0.5
+0.0
-0.6
-0.2
-0.5
phage
T7_phage 0.00015625 MOI TC3
+0.5
+0.1
-0.4
-0.2
-0.8
plasmid transformation
vcDART vector transformation; liquid outgrowth assay
-0.3
-0.2
+0.9
-0.2
-0.2
stress
LB Anaerobic with Benzethonium chloride 0.00003125 mM
+0.2
-0.8
+0.4
+0.5
-0.1
stress
LB Anaerobic with Spectinomycin 0.0000625 mM
-0.3
-0.4
+0.9
+0.2
-0.3
control
PBS_cage_2_mouse_3_Cecum_40 hr
-0.3
+0.3
+0.1
-0.7
+0.8
phage
Phage_N4_cage_3_mouse_4_Cecum_40 hr
+0.6
-0.5
+0.1
+0.4
-0.3
control
PBS_cage_2_mouse_1_Cecum_40 hr
+0.4
-0.1
-0.1
-0.7
+0.9
stress
LB Aerobic with Phenazine ethosulfate 0.0000625 mM
-0.2
+0.8
+0.1
+0.4
-0.4
stress
LB Anaerobic with Vancomycin Hydrochloride from Streptomyces orientalis 0.00003125 mM
-0.3
+0.8
-0.0
-0.3
+0.4
control
PBS_cage_2_mice _Feces_22 hr
+0.4
-0.1
+0.0
-0.3
+0.9
stress
LB Anaerobic with Hygromycin B 0.00025 mM
-0.2
-0.5
+1.6
+0.1
+0.2
stress
LB Anaerobic with Cefoxitin 0.000003125 mM
+0.5
+1.1
-0.0
-0.2
-0.1
control
PBS_cage_2_mice _Feces_40 hr
+0.3
+0.2
-0.0
-0.2
+1.1
stress
LB Anaerobic with Furaltadone 0.000015625 mM
-0.2
-0.0
+0.6
+0.7
+0.3
phage
RB68
-0.1
-0.2
+0.5
-0.0
+1.3
stress
LB Anaerobic with Cefoxitin 0.000003125 mM
+0.2
+1.1
+0.1
-0.2
+0.3
stress
Bacitracin 1 mg/ml
-0.2
+0.3
+0.7
+0.5
+0.4
stress
LB Anaerobic with Hygromycin B 0.00025 mM
-0.1
-0.4
+2.1
+0.2
-0.1
control
PBS_cage_2_mouse_2_Cecum_40 hr
+0.7
+0.2
-0.3
-0.0
+1.3
phage
Ste41
+0.9
-0.2
+0.5
+0.1
+1.2
stress
Butanol 1.25 vol%
+0.0
+0.0
+2.7
+0.2
+0.0
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