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Cofit
Protein
Homologs
Fitness for 5 genes in
Escherichia coli BW25113
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
yaeB and rcsF overlap by 4 nucleotides
rcsF and metQ are separated by 117 nucleotides
metQ and metI are separated by 39 nucleotides
metI and metN overlap by 8 nucleotides
b0195: yaeB - hypothetical protein (NCBI), at 218,887 to 219,594
yaeB
b0196: rcsF - predicted outer membrane protein, signal (NCBI), at 219,591 to 219,995
rcsF
b0197: metQ - DL-methionine transporter subunit (NCBI), at 220,113 to 220,928
metQ
b0198: metI - DL-methionine transporter subunit (NCBI), at 220,968 to 221,621
metI
b0199: metN - DL-methionine transporter subunit (NCBI), at 221,614 to 222,645
metN
Group
Condition
b0195
b0196
b0197
b0198
b0199
yaeB
rcsF
metQ
metI
metN
phage
Laval1374
-0.3
-6.7
-0.1
+0.2
+0.0
phage
Laval1374
-0.3
-5.8
-0.2
+0.2
-0.0
stress
Chloride 750 mM
-0.1
-3.7
+0.3
-0.1
-0.2
M9 Acetate 0.5% aerobic
-0.0
+0.2
-1.0
-1.3
-1.1
carbon source
acetate (C)
+0.1
-0.0
-1.4
-1.0
-0.7
M9 Acetate 0.5% aerobic
+0.3
+0.2
-1.1
-1.2
-1.1
predation
48 hr rep2_HD100_10fold_dilution
-0.1
+0.1
-0.8
-0.9
-0.8
carbon source
Glycolic Acid (C)
+0.5
+0.3
-1.1
-1.3
-0.8
phage
Phage_N4_cage_3_mouse_3_Cecum_40 hr
-0.9
-0.4
-0.3
-0.2
-0.5
control
PBS_cage_1_mice _Feces_40 hr
-0.2
-0.5
-0.5
-0.1
-0.9
phage
T7_phage 0.00015625 MOI TC3
+0.0
-0.8
-0.8
-0.2
-0.3
predation
48 hr rep3_HD100_10fold_dilution
+0.0
+0.0
-0.6
-0.7
-0.7
carbon source
Acetate (C)
+0.1
+0.1
-0.8
-0.7
-0.7
carbon source
acetate (C)
+0.3
+0.1
-0.9
-0.8
-0.6
carbon source
Acetate (C)
+0.2
-0.1
-0.8
-0.5
-0.5
carbon source
Glycolic Acid (C)
+0.2
+0.7
-0.6
-1.1
-0.8
phage
Phage_N4_cage_3_mice _Feces_40 hr
-0.4
+0.3
-0.6
-0.4
-0.4
carbon source
succinate (C)
+0.2
+0.3
-1.0
-0.6
-0.5
stress
Bacitracin 1 mg/ml
-0.3
-1.3
-0.1
+0.5
+0.0
stress
Cephalothin 0.01 mg/ml
+0.2
-0.8
+0.3
-0.4
-0.4
phage
Ste41
-0.7
-0.9
+0.3
+0.2
+0.2
phage
Ste41
-0.5
-0.9
+0.9
+0.3
-0.1
carbon source
Ying_sugar7 rep C; time point 3
+0.1
-0.7
+0.5
+0.3
+0.5
plasmid transformation
vcDART vector transformation; liquid outgrowth assay
+0.4
+0.6
-0.7
+0.5
+0.2
carbon source
Ying_Nucleobase14 rep C; time point 3
+0.2
-0.2
+0.9
+0.5
+0.5
carbon source
Ying_Nucleobase14 rep B; time point 3
+0.2
+0.0
+1.1
+0.3
+0.5
carbon source
D-Serine (C)
+0.4
+0.1
+0.5
+0.5
+0.6
stress
Benzalkonium Chloride 0.004 mg/ml
+0.9
+0.5
+0.2
+0.4
+0.3
carbon source
Ying_Nucleobase14 rep A; time point 3
+0.3
+0.3
+0.9
+0.3
+0.5
nitrogen source
Putrescine (N)
+0.6
+0.1
+0.5
+0.8
+0.6
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