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Protein
Homologs
Fitness for 5 genes in
Escherichia coli BW25113
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500 nt
ilvH and fruR are separated by 179 nucleotides
fruR and mraZ are separated by 601 nucleotides
mraZ and mraW are separated by 1 nucleotides
mraW and ftsL overlap by 4 nucleotides
b0078: ilvH - acetolactate synthase small subunit (NCBI), at 87,357 to 87,848
ilvH
b0080: fruR - DNA-binding transcriptional dual regulator (NCBI), at 88,028 to 89,032
fruR
b0081: mraZ - hypothetical protein (NCBI), at 89,634 to 90,092
mraZ
b0082: mraW - S-adenosyl-methyltransferase (NCBI), at 90,094 to 91,035
mraW
b0083: ftsL - membrane bound cell division protein at septum containing leucine zipper motif (NCBI), at 91,032 to 91,397
ftsL
Group
Condition
b0078
b0080
b0081
b0082
b0083
ilvH
fruR
mraZ
mraW
ftsL
carbon source
Ying_OrganicAcid7 rep C; time point 3
-8.0
-6.7
-0.6
+1.0
N.D.
carbon source
Ying_OrganicAcid7 rep A; time point 3
-7.3
-6.9
-0.6
+1.1
N.D.
carbon source
Ying_OrganicAcid7 rep B; time point 3
-6.1
-7.1
-0.4
+1.2
N.D.
carbon source
Ying_OrganicAcid7 rep A; time point 2
-5.7
-6.5
-0.6
+1.1
N.D.
carbon source
Ying_OrganicAcid7 rep B; time point 2
-5.2
-5.4
-0.7
+0.9
N.D.
carbon source
D,L-Lactate (C)
-3.8
-5.3
-0.7
-0.2
N.D.
carbon source
Ying_OrganicAcid7 rep C; time point 2
-5.2
-4.8
-0.3
+0.9
N.D.
carbon source
pyruvate (C)
-3.6
-4.6
-0.5
-0.5
N.D.
carbon source
D-Serine (C)
-3.9
-4.1
-0.7
-0.5
N.D.
carbon source
pyruvate (C)
-3.4
-4.2
-0.7
-0.3
N.D.
carbon source
D-Serine (C)
-3.6
-4.0
-0.8
+0.1
N.D.
nitrogen source
D-Serine (N)
-6.4
-0.6
-0.5
-0.7
N.D.
carbon source
D,L-Lactate (C)
-3.6
-4.4
-0.5
+0.3
N.D.
carbon source
Ying_Nucleobase14 rep A; time point 3
-0.9
-6.9
-1.0
+0.8
N.D.
carbon source
D-Lactate (C)
-2.8
-5.1
-0.3
+0.3
N.D.
stress
2,4-Dinitrophenol 2 mM
-0.3
-2.6
-0.6
-4.4
N.D.
carbon source
D-Galacturonic Acid (C)
-4.5
-2.9
-0.2
-0.1
N.D.
carbon source
D-Lactate (C)
-3.0
-4.8
-0.5
+0.6
N.D.
carbon source
Ying_Nucleobase14 rep C; time point 3
-0.6
-6.8
-0.9
+0.9
N.D.
carbon source
D-Galacturonic Acid (C) MOPS
-4.8
-2.6
-0.4
+0.4
N.D.
carbon source
Ying_sugar7 rep A; time point 3
-4.9
-1.7
-0.8
+0.4
N.D.
carbon source
D-Galacturonic Acid (C) M9
-4.3
-2.9
-0.3
+0.6
N.D.
carbon source
L-Malic (C)
-3.1
-4.6
-0.4
+1.3
N.D.
carbon source
Ying_Nucleobase14 rep B; time point 3
-0.4
-6.2
-0.9
+1.0
N.D.
carbon source
L-Malic (C)
-2.5
-4.5
-0.1
+1.6
N.D.
carbon source
acetate (C)
-0.8
-5.0
-0.2
+2.2
N.D.
carbon source
acetate (C)
-0.8
-4.9
-0.4
+2.5
N.D.
carbon source
Glycolic Acid (C)
-1.0
-4.6
-0.2
+2.2
N.D.
carbon source
Glycolic Acid (C)
-1.1
-4.0
-0.5
+2.2
N.D.
carbon source
Acetate (C)
-0.4
-4.6
-0.5
+2.5
N.D.
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