Gene info for PfGW456L13_5145 in Pseudomonas fluorescens GW456-L13

Updated annotation (from data): 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
Rationale: Specifically important for utilizing L-Valine. Automated validation from mutant phenotype: the predicted function (3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN) was linked to the condition via a MetaCyc pathway. This annotation was also checked manually.
Original annotation: 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
Type 1: Protein-coding gene
Located on scaffold scaffold1/0|quiver|pilon, - strand, nucleotides 5,741,269 to 5,742,156
See nucleotide sequence around PfGW456L13_5145 or for all of scaffold scaffold1/0|quiver|pilon

Other databases: uniprot: A0A293QV72

Nearby Genes

500 ntPfGW456L13_5140 and PfGW456L13_5141 are separated by 217 nucleotidesPfGW456L13_5141 and PfGW456L13_5142 are separated by 42 nucleotidesPfGW456L13_5142 and PfGW456L13_5143 are separated by 49 nucleotidesPfGW456L13_5143 and PfGW456L13_5144 are separated by 106 nucleotidesPfGW456L13_5144 and PfGW456L13_5145 are separated by 173 nucleotidesPfGW456L13_5145 and PfGW456L13_5146 are separated by 10 nucleotidesPfGW456L13_5146 and PfGW456L13_5147 are separated by 150 nucleotidesPfGW456L13_5147 and PfGW456L13_5148 are separated by 166 nucleotidesPfGW456L13_5148 and PfGW456L13_5149 are separated by 335 nucleotidesPfGW456L13_5149 and PfGW456L13_5150 overlap by 4 nucleotides PfGW456L13_5140 - membrane protein, putative, at 5,737,736 to 5,738,500 _5140 PfGW456L13_5141 - Hydrogen peroxide-inducible genes activator, at 5,738,718 to 5,739,602 _5141 PfGW456L13_5142 - Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17), at 5,739,645 to 5,740,223 _5142 PfGW456L13_5143 - transcriptional regulator, MerR family, at 5,740,273 to 5,740,644 _5143 PfGW456L13_5144 - FIG00954870: hypothetical protein, at 5,740,751 to 5,741,095 _5144 PfGW456L13_5145 - 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data), at 5,741,269 to 5,742,156 _5145 PfGW456L13_5146 - Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) (from data), at 5,742,167 to 5,743,693 _5146 PfGW456L13_5147 - Transcriptional regulator, LysR family, at 5,743,844 to 5,744,791 _5147 PfGW456L13_5148 - hypothetical protein, at 5,744,958 to 5,745,362 _5148 PfGW456L13_5149 - Transcriptional regulator, LysR family, at 5,745,698 to 5,745,838 _5149 PfGW456L13_5150 - Exodeoxyribonuclease V alpha chain (EC 3.1.11.5), at 5,745,835 to 5,747,928 _5150
Locus Name Description Strand Phenotype
PfGW456L13_5140 membrane protein, putative - insig.
PfGW456L13_5141 Hydrogen peroxide-inducible genes activator + insig.
PfGW456L13_5142 Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17) + insig.
PfGW456L13_5143 transcriptional regulator, MerR family + insig.
PfGW456L13_5144 FIG00954870: hypothetical protein + insig.
PfGW456L13_5145 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data) - strong
PfGW456L13_5146 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) (from data) - strong
PfGW456L13_5147 Transcriptional regulator, LysR family + strong
PfGW456L13_5148 hypothetical protein - insig.
PfGW456L13_5149 Transcriptional regulator, LysR family + insig.
PfGW456L13_5150 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) - sig.

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