Gene info for PfGW456L13_3543 in Pseudomonas fluorescens GW456-L13

Updated annotation (from data): Dihydrolipoyl dehydrogenase (EC 1.8.1.4)
Rationale: Specifically important for utilizing L-Isoleucine; L-Valine. Automated validation from mutant phenotype: the predicted function (1.8.1.4) was linked to the condition via a SEED subsystem. This annotation was also checked manually.
Original annotation: Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4)
Type 1: Protein-coding gene
Located on scaffold scaffold1/0|quiver|pilon, + strand, nucleotides 3,985,634 to 3,987,016
See nucleotide sequence around PfGW456L13_3543 or for all of scaffold scaffold1/0|quiver|pilon

Other databases: uniprot: A0A293QMW4

Nearby Genes

500 ntPfGW456L13_3538 and PfGW456L13_3539 are separated by 128 nucleotidesPfGW456L13_3539 and PfGW456L13_3540 are separated by 185 nucleotidesPfGW456L13_3540 and PfGW456L13_3541 are separated by 1 nucleotidesPfGW456L13_3541 and PfGW456L13_3542 are separated by 0 nucleotidesPfGW456L13_3542 and PfGW456L13_3543 are separated by 3 nucleotidesPfGW456L13_3543 and PfGW456L13_3544 are separated by 208 nucleotidesPfGW456L13_3544 and PfGW456L13_3545 are separated by 160 nucleotidesPfGW456L13_3545 and PfGW456L13_3546 are separated by 78 nucleotidesPfGW456L13_3546 and PfGW456L13_3547 are separated by 11 nucleotidesPfGW456L13_3547 and PfGW456L13_3548 are separated by 13 nucleotides PfGW456L13_3538 - FIG146518: Zn-dependent hydrolases, including glyoxylases, at 3,980,391 to 3,981,254 _3538 PfGW456L13_3539 - Transcriptional regulator BkdR of isoleucine and valine catabolism operon, at 3,981,383 to 3,981,871 _3539 PfGW456L13_3540 - branched-chain alpha-ketoacid dehydrogenase, E1 component alpha subunit (EC 1.2.4.4) (from data), at 3,982,057 to 3,983,292 _3540 PfGW456L13_3541 - branched-chain alpha-ketoacid dehydrogenase, E1 component beta subunit (EC 1.2.4.4) (from data), at 3,983,294 to 3,984,352 _3541 PfGW456L13_3542 - Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) (from data), at 3,984,353 to 3,985,630 _3542 PfGW456L13_3543 - Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (from data), at 3,985,634 to 3,987,016 _3543 PfGW456L13_3544 - Branched-chain amino acid aminotransferase (EC 2.6.1.42), at 3,987,225 to 3,988,244 _3544 PfGW456L13_3545 - Transcriptional regulator, ArsR family, at 3,988,405 to 3,989,169 _3545 PfGW456L13_3546 - putative cytochrome p450 oxidoreductase, at 3,989,248 to 3,990,357 _3546 PfGW456L13_3547 - Cobalt-zinc-cadmium resistance protein CzcD, at 3,990,369 to 3,991,301 _3547 PfGW456L13_3548 - FIG074102: hypothetical protein, at 3,991,315 to 3,991,590 _3548
Locus Name Description Strand Phenotype
PfGW456L13_3538 FIG146518: Zn-dependent hydrolases, including glyoxylases + strong
PfGW456L13_3539 Transcriptional regulator BkdR of isoleucine and valine catabolism operon - strong
PfGW456L13_3540 branched-chain alpha-ketoacid dehydrogenase, E1 component alpha subunit (EC 1.2.4.4) (from data) + strong
PfGW456L13_3541 branched-chain alpha-ketoacid dehydrogenase, E1 component beta subunit (EC 1.2.4.4) (from data) + strong
PfGW456L13_3542 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) (from data) + strong
PfGW456L13_3543 Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (from data) + strong
PfGW456L13_3544 Branched-chain amino acid aminotransferase (EC 2.6.1.42) + strong
PfGW456L13_3545 Transcriptional regulator, ArsR family - insig.
PfGW456L13_3546 putative cytochrome p450 oxidoreductase + insig.
PfGW456L13_3547 Cobalt-zinc-cadmium resistance protein CzcD - strong
PfGW456L13_3548 FIG074102: hypothetical protein - no data

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