Gene info for PP_5260 in Pseudomonas putida KT2440

Updated annotation (from data): 2-oxoadipate decarboxylase/hydroxylase (2-hydroxyglutarate synthase)
Rationale: Specifically important in carbon source L-Lysine; carbon source D-Lysine. This is part of the pathway from D-lysine to 2-oxoglutarate. For biochemical evidence that this enzyme forms 2-hydroxyglutarate, see https://doi.org/10.1101/450254
Original annotation: metalloprotein, putative enzyme
Type 1: Protein-coding gene
Located on scaffold AE015451, + strand, nucleotides 6,005,138 to 6,006,532
See nucleotide sequence around PP_5260 or for all of scaffold AE015451

Other databases: NCBI, uniprot: Q88CC1

Nearby Genes

500 ntPP_5255 and PP_5256 are separated by 320 nucleotidesPP_5256 and PP_5257 are separated by 108 nucleotidesPP_5257 and PP_5258 are separated by 145 nucleotidesPP_5258 and PP_5259 are separated by 135 nucleotidesPP_5259 and PP_5260 are separated by 175 nucleotidesPP_5260 and PP_5261 are separated by 98 nucleotidesPP_5261 and PP_5262 are separated by 157 nucleotidesPP_5262 and PP_5263 are separated by 81 nucleotidesPP_5263 and PP_5264 are separated by 296 nucleotidesPP_5264 and PP_5265 are separated by 64 nucleotides PP_5255: PP_5255 - putative hydrolase, at 5,998,516 to 5,999,145 _5255 PP_5256: PP_5256 - Cyclic nucleotide-binding protein, at 5,999,466 to 6,000,893 _5256 PP_5257: PP_5257 - L-pipecolate oxidase, at 6,001,002 to 6,002,300 _5257 PP_5258: PP_5258 - L-piperidine-6-carboxylate dehydrogenase, at 6,002,446 to 6,003,936 _5258 PP_5259: PP_5259 - Transcriptional regulator, LysR family, at 6,004,072 to 6,004,962 _5259 PP_5260: PP_5260 - 2-oxoadipate decarboxylase/hydroxylase (2-hydroxyglutarate synthase) (from data), at 6,005,138 to 6,006,532 _5260 PP_5261: PP_5261 - Transcriptional regulator, LysR family, at 6,006,631 to 6,007,557 _5261 PP_5262: PP_5262 - Probable multidrug resistance protein NorM, at 6,007,715 to 6,009,103 _5262 PP_5263: PP_5263 - GGDEF domain protein, at 6,009,185 to 6,010,852 _5263 PP_5264: PP_5264 - helicase a single-stranded DNA dependent ATPase, at 6,011,149 to 6,013,158 _5264 PP_5265: PP_5265 - Xanthine phosphoribosyltransferase, at 6,013,223 to 6,013,795 _5265
Locus Name Description Strand Phenotype
PP_5255 PP_5255 putative hydrolase - insig.
PP_5256 PP_5256 Cyclic nucleotide-binding protein + insig.
PP_5257 PP_5257 L-pipecolate oxidase - strong
PP_5258 PP_5258 L-piperidine-6-carboxylate dehydrogenase - strong
PP_5259 PP_5259 Transcriptional regulator, LysR family + insig.
PP_5260 PP_5260 2-oxoadipate decarboxylase/hydroxylase (2-hydroxyglutarate synthase) (from data) + strong
PP_5261 PP_5261 Transcriptional regulator, LysR family - insig.
PP_5262 PP_5262 Probable multidrug resistance protein NorM + strong
PP_5263 PP_5263 GGDEF domain protein - sig.
PP_5264 PP_5264 helicase a single-stranded DNA dependent ATPase + no data
PP_5265 PP_5265 Xanthine phosphoribosyltransferase + insig.

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