Gene info for PP_3590 in Pseudomonas putida KT2440

Updated annotation (from data): aromatic-amino-acid transaminase (EC 2.6.1.57)
Rationale: Required for utilization of phenylalanine or tyrosine as the sole nitrogen source (PMID:38323821). Has phenotypes on a variety of carbon sources, which probably indicates a (partly genetically-redundant) biosynthetic role as well. May also act on isoleucine or on 2-aminoadipate, as part of pipecolate degradation (PMC9004399). Was previously proposed to be D-lysine aminotransferase, but is not important for utilizing D-lysine (PMID:38323821). 71% identical to E. coli tyrB.
Original annotation: D-lysine aminotransferase
Type 1: Protein-coding gene
Located on scaffold AE015451, - strand, nucleotides 4,079,580 to 4,080,776
See nucleotide sequence around PP_3590 or for all of scaffold AE015451

Other databases: NCBI, uniprot: Q88GX7

Nearby Genes

500 ntPP_3585 and PP_3586 are separated by 623 nucleotidesPP_3586 and PP_3587 are separated by 440 nucleotidesPP_3587 and PP_3588 are separated by 300 nucleotidesPP_3588 and PP_3589 are separated by 72 nucleotidesPP_3589 and PP_3590 are separated by 383 nucleotidesPP_3590 and PP_3591 are separated by 162 nucleotidesPP_3591 and PP_3592 are separated by 118 nucleotidesPP_3592 and PP_3593 are separated by 22 nucleotidesPP_3593 and PP_3594 are separated by 104 nucleotidesPP_3594 and PP_3595 overlap by 4 nucleotides PP_3585: PP_3585 - multidrug efflux transport system - putative membrane fusion protein, at 4,072,155 to 4,073,462 _3585 PP_3586: PP_3586 - transposase, at 4,074,086 to 4,075,414 _3586 PP_3587: PP_3587 - lipid hydroperoxide peroxidase, at 4,075,855 to 4,076,355 _3587 PP_3588: PP_3588 - Multidrug resistance transporter, Bcr/CflA family, at 4,076,656 to 4,077,843 _3588 PP_3589: PP_3589 - serine:H+ symport permease, threonine-insensitive, at 4,077,916 to 4,079,196 _3589 PP_3590: PP_3590 - aromatic-amino-acid transaminase (EC 2.6.1.57) (from data), at 4,079,580 to 4,080,776 _3590 PP_3591: PP_3591 - Delta 1-piperideine-2-carboxylate reductase, at 4,080,939 to 4,081,937 _3591 PP_3592: PP_3592 - Transcriptional regulator, RpiR family, at 4,082,056 to 4,082,979 _3592 PP_3593: PP_3593 - L-lysine and D-lysine ABC transporter, substrate-binding component (from data), at 4,083,002 to 4,083,754 _3593 PP_3594: PP_3594 - L-lysine and D-lysine ABC transporter, permease component 1 (from data), at 4,083,859 to 4,084,578 _3594 PP_3595: PP_3595 - L-lysine and D-lysine ABC transporter, permease component 2 (from data), at 4,084,575 to 4,085,285 _3595
Locus Name Description Strand Phenotype
PP_3585 PP_3585 multidrug efflux transport system - putative membrane fusion protein - insig.
PP_3586 PP_3586 transposase - no data
PP_3587 PP_3587 lipid hydroperoxide peroxidase - strong
PP_3588 PP_3588 Multidrug resistance transporter, Bcr/CflA family + insig.
PP_3589 PP_3589 serine:H+ symport permease, threonine-insensitive - insig.
PP_3590 PP_3590 aromatic-amino-acid transaminase (EC 2.6.1.57) (from data) - strong
PP_3591 PP_3591 Delta 1-piperideine-2-carboxylate reductase - strong
PP_3592 PP_3592 Transcriptional regulator, RpiR family + strong
PP_3593 PP_3593 L-lysine and D-lysine ABC transporter, substrate-binding component (from data) + strong
PP_3594 PP_3594 L-lysine and D-lysine ABC transporter, permease component 1 (from data) + strong
PP_3595 PP_3595 L-lysine and D-lysine ABC transporter, permease component 2 (from data) + strong

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