Gene info for PS417_12125 in Pseudomonas simiae WCS417

Updated annotation (from data): D-glucosaminate dehydratase (EC 4.3.1.9)
Rationale: Specifically important for: D-Glucosamine Hydrochloride. This enzyme had not previously been linked to a gene. This is the second step in catabolism of glucosamine, and the 'beta' form of the enzyme was expected to be PLP-dependent and about this size. Iwamoto et al (2003) purified a non-specific 'alpha' enzyme for this reaction (PMID: 12686150)
Original annotation: amino acid deaminase
Type 1: Protein-coding gene
Located on scaffold CP007637, + strand, nucleotides 2,630,658 to 2,631,866
See nucleotide sequence around PS417_12125 or for all of scaffold CP007637

Other databases: NCBI, IMG: 2586031061, uniprot: A0A1N7U313

Nearby Genes

500 ntPS417_12100 and PS417_12105 are separated by 11 nucleotidesPS417_12105 and PS417_12110 overlap by 4 nucleotidesPS417_12110 and PS417_12115 are separated by 16 nucleotidesPS417_12115 and PS417_12120 are separated by 166 nucleotidesPS417_12120 and PS417_12125 are separated by 9 nucleotidesPS417_12125 and PS417_12130 are separated by 10 nucleotidesPS417_12130 and PS417_12135 are separated by 63 nucleotidesPS417_12135 and PS417_12140 are separated by 43 nucleotidesPS417_12140 and PS417_12145 are separated by 135 nucleotidesPS417_12145 and PS417_12150 are separated by 100 nucleotides PS417_12100: PS417_12100 - amino acid ABC transporter permease, at 2,627,196 to 2,627,858 _12100 PS417_12105: PS417_12105 - ABC transporter permease, at 2,627,870 to 2,628,532 _12105 PS417_12110: PS417_12110 - ATP-binding protein, at 2,628,529 to 2,629,311 _12110 PS417_12115: PS417_12115 - endoribonuclease L-PSP, at 2,629,328 to 2,629,717 _12115 PS417_12120: PS417_12120 - IclR family transcriptional regulator, at 2,629,884 to 2,630,648 _12120 PS417_12125: PS417_12125 - D-glucosaminate dehydratase (EC 4.3.1.9) (from data), at 2,630,658 to 2,631,866 _12125 PS417_12130: PS417_12130 - ketodeoxygluconokinase, at 2,631,877 to 2,632,806 _12130 PS417_12135: PS417_12135 - peptidylprolyl isomerase, at 2,632,870 to 2,633,145 _12135 PS417_12140: PS417_12140 - histidine kinase, at 2,633,189 to 2,635,684 _12140 PS417_12145: PS417_12145 - acetoacetyl-CoA synthetase, at 2,635,820 to 2,637,778 _12145 PS417_12150: PS417_12150 - 3-hydroxybutyrate dehydrogenase, at 2,637,879 to 2,638,652 _12150
Locus Name Description Strand Phenotype
PS417_12100 PS417_12100 amino acid ABC transporter permease + sig.
PS417_12105 PS417_12105 ABC transporter permease + sig.
PS417_12110 PS417_12110 ATP-binding protein + insig.
PS417_12115 PS417_12115 endoribonuclease L-PSP + no data
PS417_12120 PS417_12120 IclR family transcriptional regulator + strong
PS417_12125 PS417_12125 D-glucosaminate dehydratase (EC 4.3.1.9) (from data) + strong
PS417_12130 PS417_12130 ketodeoxygluconokinase + insig.
PS417_12135 PS417_12135 peptidylprolyl isomerase - sig.
PS417_12140 PS417_12140 histidine kinase - insig.
PS417_12145 PS417_12145 acetoacetyl-CoA synthetase - insig.
PS417_12150 PS417_12150 3-hydroxybutyrate dehydrogenase - no data

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