Gene info for Echvi_4214 in Echinicola vietnamensis KMM 6221, DSM 17526

Updated annotation (from data): lysine/tyrosine outer membrane transporter, TonB-dependent receptor component
Rationale: Specifically important in nitrogen source L-Lysine; nitrogen source L-tyrosine disodium salt. Echvi_4214 is a TonB-dependent outer membrane transporter that is required for utilization of lysine. Mutants also have a defect in tyrosine utilization. It probably functions with Echvi_4215, which is cofit and part of a conserved gene cluster. Inner membrane protein Echvi_4216 (PFam PepSY_TM) is also conserved nearby but does not have a phenotype; it may have a regulatory role.
Original annotation: Outer membrane receptor proteins, mostly Fe transport
Type 1: Protein-coding gene
Located on scaffold Echvi_Contig97.1, + strand, nucleotides 5,046,074 to 5,048,524
See nucleotide sequence around Echvi_4214 or for all of scaffold Echvi_Contig97.1

Other databases: NCBI, uniprot: L0G6D2

Nearby Genes

500 ntEchvi_4209 and Echvi_4210 are separated by 68 nucleotidesEchvi_4210 and Echvi_4211 are separated by 3 nucleotidesEchvi_4211 and Echvi_4212 are separated by 290 nucleotidesEchvi_4212 and Echvi_4213 are separated by 306 nucleotidesEchvi_4213 and Echvi_4214 are separated by 372 nucleotidesEchvi_4214 and Echvi_4215 are separated by 26 nucleotidesEchvi_4215 and Echvi_4216 are separated by 195 nucleotidesEchvi_4216 and Echvi_4217 are separated by 290 nucleotidesEchvi_4217 and Echvi_4218 overlap by 11 nucleotidesEchvi_4218 and Echvi_4219 overlap by 4 nucleotides Echvi_4209: Echvi_4209 - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, at 5,036,542 to 5,037,207 _4209 Echvi_4210: Echvi_4210 - RND family efflux transporter, MFP subunit, at 5,037,276 to 5,038,439 _4210 Echvi_4211: Echvi_4211 - heavy metal efflux pump (cobalt-zinc-cadmium), at 5,038,443 to 5,042,774 _4211 Echvi_4212: Echvi_4212 - hypothetical protein, at 5,043,065 to 5,044,603 _4212 Echvi_4213: Echvi_4213 - Glutamate 5-kinase, at 5,044,910 to 5,045,701 _4213 Echvi_4214: Echvi_4214 - lysine/tyrosine outer membrane transporter, TonB-dependent receptor component (from data), at 5,046,074 to 5,048,524 _4214 Echvi_4215: Echvi_4215 - lysine/tyrosine outer membrane transporter, accessory component (from data), at 5,048,551 to 5,049,885 _4215 Echvi_4216: Echvi_4216 - Uncharacterized iron-regulated membrane protein, at 5,050,081 to 5,051,337 _4216 Echvi_4217: Echvi_4217 - efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family, at 5,051,628 to 5,053,079 _4217 Echvi_4218: Echvi_4218 - RND family efflux transporter, MFP subunit, at 5,053,069 to 5,054,256 _4218 Echvi_4219: Echvi_4219 - Cation/multidrug efflux pump, at 5,054,253 to 5,057,354 _4219
Locus Name Description Strand Phenotype
Echvi_4209 Echvi_4209 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - strong
Echvi_4210 Echvi_4210 RND family efflux transporter, MFP subunit - strong
Echvi_4211 Echvi_4211 heavy metal efflux pump (cobalt-zinc-cadmium) - strong
Echvi_4212 Echvi_4212 hypothetical protein - insig.
Echvi_4213 Echvi_4213 Glutamate 5-kinase + insig.
Echvi_4214 Echvi_4214 lysine/tyrosine outer membrane transporter, TonB-dependent receptor component (from data) + strong
Echvi_4215 Echvi_4215 lysine/tyrosine outer membrane transporter, accessory component (from data) + strong
Echvi_4216 Echvi_4216 Uncharacterized iron-regulated membrane protein + insig.
Echvi_4217 Echvi_4217 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family + insig.
Echvi_4218 Echvi_4218 RND family efflux transporter, MFP subunit + insig.
Echvi_4219 Echvi_4219 Cation/multidrug efflux pump + insig.

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