Gene info for Echvi_2564 in Echinicola vietnamensis KMM 6221, DSM 17526

Updated annotation (from data): DNA repair nuclease with dnaQ and GIY-YIG domains
Rationale: Specifically important in stress Cisplatin. Contains a domain that is similar to DnaQ (the epsilon subunit of replicative DNA polymerase which is the exonuclease for proofreading) as well as a GIY-YIG nuclease domain.This protein is often misannotated as DnaQ, but the proofreading activity of the replicative DNA polymerase seems to reside in the same polypeptide as the catalytic subunit (see Echvi_2020 or discussion in PMC3919608).
Original annotation: exonuclease, DNA polymerase III, epsilon subunit family
Type 1: Protein-coding gene
Located on scaffold Echvi_Contig97.1, - strand, nucleotides 3,040,834 to 3,042,207
See nucleotide sequence around Echvi_2564 or for all of scaffold Echvi_Contig97.1

Other databases: NCBI, uniprot: L0G1B7

Nearby Genes

500 ntEchvi_2559 and Echvi_2560 are separated by 148 nucleotidesEchvi_2560 and Echvi_2561 overlap by 4 nucleotidesEchvi_2561 and Echvi_2562 are separated by 59 nucleotidesEchvi_2562 and Echvi_2563 are separated by 215 nucleotidesEchvi_2563 and Echvi_2564 are separated by 666 nucleotidesEchvi_2564 and Echvi_2565 are separated by 41 nucleotidesEchvi_2565 and Echvi_2566 are separated by 137 nucleotidesEchvi_2566 and Echvi_2567 are separated by 52 nucleotidesEchvi_2567 and Echvi_2568 are separated by 421 nucleotidesEchvi_2568 and Echvi_2569 are separated by 110 nucleotides Echvi_2559: Echvi_2559 - 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase, at 3,034,467 to 3,036,794 _2559 Echvi_2560: Echvi_2560 - PAS domain S-box, at 3,036,943 to 3,037,335 _2560 Echvi_2561: Echvi_2561 - Acyl-CoA hydrolase, at 3,037,332 to 3,037,724 _2561 Echvi_2562: Echvi_2562 - Predicted phosphatase, at 3,037,784 to 3,039,193 _2562 Echvi_2563: Echvi_2563 - hypothetical protein, at 3,039,409 to 3,040,167 _2563 Echvi_2564: Echvi_2564 - DNA repair nuclease with dnaQ and GIY-YIG domains (from data), at 3,040,834 to 3,042,207 _2564 Echvi_2565: Echvi_2565 - DinB family., at 3,042,249 to 3,042,941 _2565 Echvi_2566: Echvi_2566 - biotin synthetase, at 3,043,079 to 3,044,056 _2566 Echvi_2567: Echvi_2567 - Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II, at 3,044,109 to 3,045,788 _2567 Echvi_2568: Echvi_2568 - hypothetical protein, at 3,046,210 to 3,047,412 _2568 Echvi_2569: Echvi_2569 - Predicted thioesterase, at 3,047,523 to 3,048,041 _2569
Locus Name Description Strand Phenotype
Echvi_2559 Echvi_2559 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase + insig.
Echvi_2560 Echvi_2560 PAS domain S-box + sig.
Echvi_2561 Echvi_2561 Acyl-CoA hydrolase + insig.
Echvi_2562 Echvi_2562 Predicted phosphatase - insig.
Echvi_2563 Echvi_2563 hypothetical protein - insig.
Echvi_2564 Echvi_2564 DNA repair nuclease with dnaQ and GIY-YIG domains (from data) - strong
Echvi_2565 Echvi_2565 DinB family. + insig.
Echvi_2566 Echvi_2566 biotin synthetase + insig.
Echvi_2567 Echvi_2567 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II - sig.
Echvi_2568 Echvi_2568 hypothetical protein + insig.
Echvi_2569 Echvi_2569 Predicted thioesterase - insig.

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