Gene info for b3603 in Escherichia coli BW25113

Name: lldP
Updated annotation (from data): (R)-lactate / (S)-lactate / glycolate:H+ symporter LldP
Rationale: This protein is annotated by EcoCyc as transporting both stereoisomers of lactate and glycolate, which is consistent with our genetic data and a more detailed study (PMID:11785976). The previous study found that yghK (glcA) also transported glycolate and was important for glycolyate utilization. We instead observed a very subtle defect of the glcA mutant during growth on glycolate (fitness = -0.5).
Original annotation: L-lactate permease (NCBI)
Type 1: Protein-coding gene
Located on scaffold 7023, + strand, nucleotides 3,775,422 to 3,777,077
See nucleotide sequence around b3603 or for all of scaffold 7023

Other databases: MicrobesOnline, EcoCyc, NCBI, IMG: 646315584, uniprot: P33231

Nearby Genes

500 ntmtlA and mtlD are separated by 229 nucleotidesmtlD and mtlR overlap by 1 nucleotidesmtlR and yibT are separated by 11 nucleotidesyibT and yibL are separated by 284 nucleotidesyibL and lldP are separated by 371 nucleotideslldP and lldR overlap by 1 nucleotideslldR and lldD overlap by 4 nucleotideslldD and yibK are separated by 197 nucleotidesyibK and cysE are separated by 52 nucleotidescysE and gpsA are separated by 79 nucleotides b3599: mtlA - Mannitol phosphotransferase system, IIA/IIB/IIC components (EC 2.7.1.197) (from data), at 3,770,304 to 3,772,217 mtlA b3600: mtlD - mannitol-1-phosphate 5-dehydrogenase (NCBI), at 3,772,447 to 3,773,595 mtlD b3601: mtlR - DNA-binding repressor (NCBI), at 3,773,595 to 3,774,182 mtlR b4554: yibT - hypothetical protein (NCBI), at 3,774,194 to 3,774,403 yibT b3602: yibL - hypothetical protein (NCBI), at 3,774,688 to 3,775,050 yibL b3603: lldP - (R)-lactate / (S)-lactate / glycolate:H+ symporter LldP (from data), at 3,775,422 to 3,777,077 lldP b3604: lldR - DNA-binding transcriptional repressor (NCBI), at 3,777,077 to 3,777,853 lldR b3605: lldD - L-lactate dehydrogenase, FMN-linked (NCBI), at 3,777,850 to 3,779,040 lldD b3606: yibK - predicted rRNA methylase (NCBI), at 3,779,238 to 3,779,711 yibK b3607: cysE - serine acetyltransferase (NCBI), at 3,779,764 to 3,780,585 cysE b3608: gpsA - NAD(P)H-dependent glycerol-3-phosphate dehydrogenase (NCBI), at 3,780,665 to 3,781,684 gpsA
Locus Name Description Strand Phenotype
b3599 mtlA Mannitol phosphotransferase system, IIA/IIB/IIC components (EC 2.7.1.197) (from data) + sig.
b3600 mtlD mannitol-1-phosphate 5-dehydrogenase (NCBI) + strong
b3601 mtlR DNA-binding repressor (NCBI) + strong
b4554 yibT hypothetical protein (NCBI) - insig.
b3602 yibL hypothetical protein (NCBI) + insig.
b3603 lldP (R)-lactate / (S)-lactate / glycolate:H+ symporter LldP (from data) + strong
b3604 lldR DNA-binding transcriptional repressor (NCBI) + strong
b3605 lldD L-lactate dehydrogenase, FMN-linked (NCBI) + sig.
b3606 yibK predicted rRNA methylase (NCBI) + insig.
b3607 cysE serine acetyltransferase (NCBI) - no data
b3608 gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase (NCBI) - no data

Or browse nearby genes

Or see the comparative fitness browser