Experiment setATCH243 for Dickeya dianthicola ME23

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PDB

200 most important genes:

  gene name fitness t score description  
DZA65_RS05310 -4.0 -10.5 thymidylate synthase compare
DZA65_RS22635 -3.9 -5.3 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
DZA65_RS00800 -3.3 -5.5 O-antigen ligase family protein compare
DZA65_RS21420 -3.3 -17.1 glutamate racemase compare
DZA65_RS22640 -3.2 -9.0 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
DZA65_RS13750 -2.8 -15.2 glucans biosynthesis glucosyltransferase MdoH compare
DZA65_RS10915 -2.7 -8.2 septation protein A compare
DZA65_RS22335 -2.7 -20.9 low affinity potassium transporter Kup compare
DZA65_RS13755 -2.5 -7.8 glucan biosynthesis protein G compare
DZA65_RS22210 -2.5 -12.3 nitrogen regulation protein NR(I) compare
DZA65_RS15380 -2.5 -9.5 4-phosphoerythronate dehydrogenase PdxB compare
DZA65_RS09990 -2.4 -3.6 3-phosphoserine/phosphohydroxythreonine transaminase compare
DZA65_RS10955 -2.4 -7.2 anthranilate phosphoribosyltransferase compare
DZA65_RS10940 -2.3 -12.1 tryptophan synthase subunit alpha compare
DZA65_RS01510 -2.1 -7.6 RNA polymerase factor sigma-54 compare
DZA65_RS10945 -2.0 -10.2 tryptophan synthase subunit beta compare
DZA65_RS10485 -2.0 -5.1 membrane protein compare
DZA65_RS10965 -2.0 -10.7 anthranilate synthase component 1 compare
DZA65_RS10960 -2.0 -2.7 C26 family cysteine hydrolase domain-containing family compare
DZA65_RS13085 -2.0 -4.8 pyridoxamine 5'-phosphate oxidase compare
DZA65_RS19655 -2.0 -2.4 adenylosuccinate synthase compare
DZA65_RS05445 -1.9 -10.1 bifunctional uridylyltransferase/uridylyl-removing protein GlnD compare
DZA65_RS21790 -1.8 -3.6 sulfurtransferase TusA compare
DZA65_RS06895 -1.8 -5.3 Tol-Pal system protein TolQ compare
DZA65_RS06900 -1.8 -1.5 colicin uptake protein TolR compare
DZA65_RS11865 -1.7 -4.6 tRNA 2-thiouridine(34) synthase MnmA compare
DZA65_RS16715 -1.7 -2.1 Fe-S cluster assembly scaffold IscU compare
DZA65_RS16610 -1.7 -10.8 IMP dehydrogenase compare
DZA65_RS20355 -1.6 -5.7 Trk system potassium transporter TrkA compare
DZA65_RS10950 -1.6 -7.5 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF compare
DZA65_RS20555 -1.6 -3.7 sulfurtransferase complex subunit TusD compare
DZA65_RS03670 -1.6 -6.2 kdo(2)-lipid IV(A) palmitoleoyltransferase compare
DZA65_RS11395 -1.6 -3.2 peptide chain release factor N(5)-glutamine methyltransferase compare
DZA65_RS18160 -1.4 -2.3 glycerate kinase compare
DZA65_RS02490 -1.4 -7.5 phosphoserine phosphatase compare
DZA65_RS10555 -1.4 -2.4 lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase compare
DZA65_RS01525 -1.4 -4.0 LPS export ABC transporter periplasmic protein LptC compare
DZA65_RS19540 -1.3 -6.9 phosphoglycerate dehydrogenase compare
DZA65_RS21565 -1.3 -8.9 agmatine deiminase compare
DZA65_RS22195 -1.3 -6.7 ribosome-dependent GTPase TypA compare
DZA65_RS19745 -1.3 -6.6 GDP-L-fucose synthase compare
DZA65_RS20840 -1.2 -4.6 two-component system response regulator OmpR compare
DZA65_RS21445 -1.2 -3.8 Si-specific NAD(P)(+) transhydrogenase compare
DZA65_RS16710 -1.2 -2.6 iron-sulfur cluster assembly protein IscA compare
DZA65_RS18650 -1.2 -3.4 alanine racemase compare
DZA65_RS16045 -1.2 -5.2 polyphosphate kinase 1 compare
DZA65_RS19515 -1.2 -6.2 non-canonical purine NTP phosphatase compare
DZA65_RS15990 -1.1 -3.6 5-(carboxyamino)imidazole ribonucleotide mutase compare
DZA65_RS03210 -1.1 -2.0 preprotein translocase subunit SecG compare
DZA65_RS16885 -1.1 -4.3 pyridoxine 5'-phosphate synthase compare
DZA65_RS20805 -1.1 -2.0 intracellular growth attenuator family protein compare
DZA65_RS13710 -1.1 -7.6 dihydroorotase compare
DZA65_RS00035 -1.1 -9.0 oligopeptidase A compare
DZA65_RS01500 -1.1 -5.0 PTS IIA-like nitrogen regulatory protein PtsN compare
DZA65_RS21090 -1.1 -1.4 tyrosine recombinase XerC compare
DZA65_RS15995 -1.0 -6.2 5-(carboxyamino)imidazole ribonucleotide synthase compare
DZA65_RS02505 -1.0 -2.6 peptide chain release factor 3 compare
DZA65_RS11120 -1.0 -5.5 mannose-6-phosphate isomerase compare
DZA65_RS19755 -1.0 -6.4 glycosyltransferase compare
DZA65_RS15340 -1.0 -7.2 colicin V production protein compare
DZA65_RS15520 -1.0 -5.6 tRNA-Arg compare
DZA65_RS13390 -1.0 -6.3 quinone-dependent dihydroorotate dehydrogenase compare
DZA65_RS21475 -1.0 -1.6 met regulon transcriptional regulator MetJ compare
DZA65_RS05490 -1.0 -6.3 sigma E protease regulator RseP compare
DZA65_RS12760 -1.0 -7.0 two-component system response regulator RstA compare
DZA65_RS19380 -1.0 -7.9 carbamoyl-phosphate synthase large subunit compare
DZA65_RS06335 -1.0 -2.7 DUF1778 domain-containing protein compare
DZA65_RS00790 -1.0 -1.8 glycosyltransferase family 4 protein compare
DZA65_RS01970 -1.0 -7.3 aspartate carbamoyltransferase compare
DZA65_RS01350 -0.9 -2.0 DNA-binding transcriptional regulator Fis compare
DZA65_RS21800 -0.9 -1.9 DcrB family lipoprotein compare
DZA65_RS06745 -0.9 -6.0 alpha-D-glucose phosphate-specific phosphoglucomutase compare
DZA65_RS16090 -0.9 -1.9 sulfurtransferase TusE compare
DZA65_RS12505 -0.9 -4.4 carboxy terminal-processing peptidase compare
DZA65_RS07170 -0.9 -4.9 UTP--glucose-1-phosphate uridylyltransferase compare
DZA65_RS21610 -0.9 -5.1 envelope stress response regulator transcription factor CpxR compare
DZA65_RS20545 -0.9 -2.4 sulfurtransferase complex subunit TusB compare
DZA65_RS03405 -0.9 -1.3 tRNA-Leu compare
DZA65_RS15335 -0.9 -7.1 amidophosphoribosyltransferase compare
DZA65_RS19685 -0.9 -1.8 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA compare
DZA65_RS18020 -0.9 -5.9 RNA polymerase sigma factor RpoS compare
DZA65_RS13875 -0.9 -6.7 flagellar filament capping protein FliD compare
DZA65_RS13030 -0.9 -6.2 orotidine-5'-phosphate decarboxylase compare
DZA65_RS00735 -0.9 -3.9 orotate phosphoribosyltransferase compare
DZA65_RS03230 -0.9 -1.6 transcription termination/antitermination protein NusA compare
DZA65_RS00530 -0.9 -1.1 DUF1471 domain-containing protein compare
DZA65_RS21495 -0.9 -3.7 cell division protein FtsN compare
DZA65_RS19730 -0.8 -6.5 GDP-mannose 4,6-dehydratase compare
DZA65_RS13670 -0.8 -3.6 phosphate acyltransferase PlsX compare
DZA65_RS12765 -0.8 -6.6 two-component system sensor histidine kinase RstB compare
DZA65_RS11020 -0.8 -5.7 HTH-type transcriptional regulator CysB compare
DZA65_RS03265 -0.8 -1.5 protein YrbN compare
DZA65_RS05840 -0.8 -1.4 peroxiredoxin C compare
DZA65_RS04215 -0.8 -2.8 SsrA-binding protein SmpB compare
DZA65_RS20970 -0.8 -5.4 gluconate operon transcriptional repressor GntR compare
DZA65_RS16830 -0.8 -7.3 phosphoribosylformylglycinamidine synthase compare
DZA65_RS13880 -0.8 -3.6 flagellar export chaperone FliS compare
DZA65_RS13025 -0.8 -1.5 stress response translation initiation inhibitor YciH compare
DZA65_RS19750 -0.8 -4.6 hypothetical protein compare
DZA65_RS05080 -0.8 -3.7 hypothetical protein compare
DZA65_RS21375 -0.8 -6.0 HTH-type transcriptional regulator HdfR compare
DZA65_RS17400 -0.8 -4.1 glutamate--cysteine ligase compare
DZA65_RS00490 -0.8 -3.8 acyl carrier protein compare
DZA65_RS03525 -0.8 -1.5 hypothetical protein compare
DZA65_RS20220 -0.8 -5.3 glucose-6-phosphate isomerase compare
DZA65_RS01710 -0.8 -1.7 outer membrane channel protein TolC compare
DZA65_RS12020 -0.8 -2.6 ribonuclease toxin immunity protein CdiI compare
DZA65_RS19720 -0.8 -6.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase compare
DZA65_RS19385 -0.8 -4.8 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit compare
DZA65_RS00360 -0.8 -3.7 MarR family transcriptional regulator compare
DZA65_RS04230 -0.8 -4.2 outer membrane protein assembly factor BamE compare
DZA65_RS12995 -0.7 -3.3 exoribonuclease II compare
DZA65_RS15370 -0.7 -3.3 tRNA pseudouridine(38-40) synthase TruA compare
DZA65_RS21370 -0.7 -5.3 DUF413 domain-containing protein compare
DZA65_RS06470 -0.7 -3.8 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
DZA65_RS12955 -0.7 -3.7 peptide ABC transporter substrate-binding protein SapA compare
DZA65_RS19725 -0.7 -6.4 phosphomannomutase/phosphoglucomutase compare
DZA65_RS12975 -0.7 -2.9 peptide ABC transporter ATP-binding protein SapF compare
DZA65_RS06420 -0.7 -5.0 phosphoribosylformylglycinamidine cyclo-ligase compare
DZA65_RS19630 -0.7 -4.5 glutathione synthase compare
DZA65_RS06025 -0.7 -1.7 DNA-binding protein HU-beta compare
DZA65_RS19350 -0.7 -2.6 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
DZA65_RS06685 -0.7 -5.6 asparagine synthase B compare
DZA65_RS10165 -0.7 -3.5 DUF496 family protein compare
DZA65_RS20550 -0.7 -1.6 sulfurtransferase complex subunit TusC compare
DZA65_RS00420 -0.7 -4.5 FtsX-like permease family protein compare
DZA65_RS01365 -0.7 -5.2 sodium/pantothenate symporter compare
DZA65_RS16635 -0.7 -1.0 outer membrane protein assembly factor BamB compare
DZA65_RS22290 -0.7 -5.9 substrate-binding domain-containing protein compare
DZA65_RS21570 -0.7 -4.8 N-carbamoylputrescine amidase compare
DZA65_RS01495 -0.7 -3.6 RNase adapter RapZ compare
DZA65_RS18920 -0.7 -2.8 D-threonate 4-phosphate dehydrogenase compare
DZA65_RS03130 -0.7 -3.8 malate dehydrogenase compare
DZA65_RS18270 -0.7 -1.9 glycerol-3-phosphate 1-O-acyltransferase PlsY compare
DZA65_RS01255 -0.7 -4.7 phosphoribosylamine--glycine ligase compare
DZA65_RS22005 -0.7 -4.1 inorganic phosphate transporter PitA compare
DZA65_RS17985 -0.7 -1.9 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase compare
DZA65_RS11145 -0.6 -3.8 ROK family transcriptional regulator compare
DZA65_RS00810 -0.6 -1.9 putative lipopolysaccharide heptosyltransferase III compare
DZA65_RS12685 -0.6 -1.4 hypothetical protein compare
DZA65_RS21075 -0.6 -1.8 magnesium/cobalt transporter CorA compare
DZA65_RS13450 -0.6 -5.2 aspartate/tyrosine/aromatic aminotransferase compare
DZA65_RS22705 -0.6 -1.7 membrane protein insertion efficiency factor YidD compare
DZA65_RS19875 -0.6 -2.0 organic hydroperoxide resistance protein compare
DZA65_RS13570 -0.6 -2.7 glycine zipper 2TM domain-containing protein compare
DZA65_RS06510 -0.6 -0.8 transcription antiterminator/RNA stability regulator CspE compare
DZA65_RS04355 -0.6 -4.5 phosphoenolpyruvate-protein phosphotransferase PtsI compare
DZA65_RS07180 -0.6 -3.6 NADP-dependent phosphogluconate dehydrogenase compare
DZA65_RS08800 -0.6 -3.4 helix-turn-helix transcriptional regulator compare
DZA65_RS11435 -0.6 -2.2 redox-regulated ATPase YchF compare
DZA65_RS07980 -0.6 -1.4 phosphonate C-P lyase system protein PhnL compare
DZA65_RS11830 -0.6 -3.6 DNA-binding transcriptional regulator KdgR compare
DZA65_RS01725 -0.6 -4.3 3',5'-cyclic-AMP phosphodiesterase compare
DZA65_RS16810 -0.6 -3.8 nitrogen regulatory protein P-II compare
DZA65_RS19680 -0.6 -3.7 RNA chaperone Hfq compare
DZA65_RS19740 -0.6 -3.2 ABC transporter ATP-binding protein compare
DZA65_RS22205 -0.6 -3.8 nitrogen regulation protein NR(II) compare
DZA65_RS06565 -0.6 -1.3 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
DZA65_RS21265 -0.6 -1.8 thioredoxin TrxA compare
DZA65_RS15135 -0.6 -1.2 hypothetical protein compare
DZA65_RS16015 -0.6 -1.4 IS200/IS605 family transposase compare
DZA65_RS19665 -0.5 -1.5 protease modulator HflC compare
DZA65_RS07565 -0.5 -1.9 CcdB family protein compare
DZA65_RS17245 -0.5 -3.5 tRNA-Asp compare
DZA65_RS06065 -0.5 -2.1 P-II family nitrogen regulator compare
DZA65_RS20835 -0.5 -3.0 two-component system sensor histidine kinase EnvZ compare
DZA65_RS13465 -0.5 -4.2 L,D-transpeptidase compare
DZA65_RS10980 -0.5 -1.8 23S rRNA pseudouridine(2605) synthase RluB compare
DZA65_RS12770 -0.5 -1.1 acid resistance repetitive basic protein Asr compare
DZA65_RS09810 -0.5 -1.2 DUF2593 family protein compare
DZA65_RS13645 -0.5 -2.0 beta-ketoacyl-ACP synthase II compare
DZA65_RS16705 -0.5 -2.0 co-chaperone HscB compare
DZA65_RS15480 -0.5 -2.9 phosphohistidine phosphatase SixA compare
DZA65_RS17835 -0.5 -1.8 oxalurate catabolism protein HpxX compare
DZA65_RS14415 -0.5 -0.9 IS4 family transposase compare
DZA65_RS09915 -0.5 -2.4 leucine-responsive transcriptional regulator Lrp compare
DZA65_RS13595 -0.5 -2.0 penicillin-binding protein activator LpoB compare
DZA65_RS09545 -0.5 -3.5 GTP-binding protein compare
DZA65_RS06120 -0.5 -4.0 efflux RND transporter periplasmic adaptor subunit compare
DZA65_RS08135 -0.5 -1.7 RraA family protein compare
DZA65_RS09455 -0.5 -1.7 DUF3413 domain-containing protein compare
DZA65_RS01260 -0.5 -4.0 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
DZA65_RS22295 -0.5 -4.1 ribokinase compare
DZA65_RS06030 -0.5 -4.2 peptidylprolyl isomerase compare
DZA65_RS00840 -0.5 -2.1 rhodanese-like domain-containing protein compare
DZA65_RS19405 -0.5 -0.9 FKBP-type peptidyl-prolyl cis-trans isomerase compare
DZA65_RS17145 -0.5 -2.2 polynucleotide adenylyltransferase PcnB compare
DZA65_RS10700 -0.5 -2.2 hypothetical protein compare
DZA65_RS01635 -0.5 -4.5 glutamate synthase large subunit compare
DZA65_RS11690 -0.5 -1.8 transcription antiterminator/RNA stability regulator CspE compare
DZA65_RS14350 -0.5 -2.2 DUF2857 domain-containing protein compare
DZA65_RS16930 -0.5 -3.6 RNA polymerase sigma factor RpoE compare
DZA65_RS10475 -0.5 -1.4 tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB compare
DZA65_RS11550 -0.5 -1.5 fatty acid metabolism transcriptional regulator FadR compare
DZA65_RS19020 -0.5 -3.5 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD compare
DZA65_RS19670 -0.5 -1.7 FtsH protease activity modulator HflK compare
DZA65_RS17795 -0.5 -2.8 allantoate amidohydrolase compare
DZA65_RS14885 -0.5 -1.4 HyaD/HybD family hydrogenase maturation endopeptidase compare
DZA65_RS01405 -0.5 -4.2 RNase E specificity factor CsrD compare
DZA65_RS22845 -0.5 -1.6 hypothetical protein compare


Specific Phenotypes

For 1 genes in this experiment

For control kanamycin in Dickeya dianthicola ME23

For control kanamycin across organisms