Experiment setATCH210 for Dickeya dianthicola 67-19

Compare to:

PDB

200 most important genes:

  gene name fitness t score description  
HGI48_RS20375 -2.3 -11.2 glutamate racemase compare
HGI48_RS18520 -2.2 -2.8 adenylosuccinate synthase compare
HGI48_RS10470 -2.0 -8.0 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF compare
HGI48_RS18375 -1.9 -5.9 inosine/xanthosine triphosphatase compare
HGI48_RS20595 -1.9 -4.5 envelope stress response regulator transcription factor CpxR compare
HGI48_RS10480 -1.9 -4.7 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein compare
HGI48_RS19055 -1.9 -2.2 elongation factor P--(R)-beta-lysine ligase compare
HGI48_RS21355 -1.8 -11.5 low affinity potassium transporter Kup compare
HGI48_RS10075 -1.7 -7.1 MAPEG family protein compare
HGI48_RS09740 -1.7 -2.8 histidinol-phosphate transaminase compare
HGI48_RS03265 -1.7 -4.5 lipoprotein NlpI compare
HGI48_RS10485 -1.7 -6.2 anthranilate synthase component 1 compare
HGI48_RS10460 -1.7 -6.3 tryptophan synthase subunit alpha compare
HGI48_RS19100 -1.7 -8.1 glucose-6-phosphate isomerase compare
HGI48_RS15850 -1.6 -7.6 RNA polymerase sigma factor RpoE compare
HGI48_RS13280 -1.6 -8.5 glucan biosynthesis protein G compare
HGI48_RS09735 -1.6 -3.2 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB compare
HGI48_RS15805 -1.6 -2.5 pyridoxine 5'-phosphate synthase compare
HGI48_RS07350 -1.6 -2.8 4Fe-4S binding protein compare
HGI48_RS18500 -1.6 -2.8 YqgE/AlgH family protein compare
HGI48_RS21475 -1.6 -3.3 acyl carrier protein compare
HGI48_RS10475 -1.6 -4.9 anthranilate phosphoribosyltransferase compare
HGI48_RS21235 -1.5 -6.4 nitrogen regulation protein NR(I) compare
HGI48_RS15185 -1.5 -1.8 5-(carboxyamino)imidazole ribonucleotide mutase compare
HGI48_RS13275 -1.5 -9.2 glucans biosynthesis glucosyltransferase MdoH compare
HGI48_RS13650 -1.5 -1.8 glycoside hydrolase family 104 protein compare
HGI48_RS04970 -1.5 -3.1 thymidylate synthase compare
HGI48_RS03655 -1.5 -2.4 MarR family transcriptional regulator compare
HGI48_RS15225 -1.4 -2.7 polyphosphate kinase 1 compare
HGI48_RS10550 -1.4 -2.3 electron transport complex subunit E compare
HGI48_RS19030 -1.4 -6.9 tRNA-Gly compare
HGI48_RS07175 -1.4 -3.5 helix-turn-helix transcriptional regulator compare
HGI48_RS05105 -1.4 -5.3 bifunctional uridylyltransferase/uridylyl-removing protein GlnD compare
HGI48_RS05730 -1.4 -7.6 SmdA family multidrug ABC transporter permease/ATP-binding protein compare
HGI48_RS20545 -1.4 -2.3 NUDIX domain-containing protein compare
HGI48_RS17565 -1.3 -3.8 alanine racemase compare
HGI48_RS13540 -1.3 -4.0 flagellar export chaperone FlgN compare
HGI48_RS05735 -1.3 -6.9 SmdB family multidrug efflux ABC transporter permease/ATP-binding protein compare
HGI48_RS00045 -1.3 -7.0 oligopeptidase A compare
HGI48_RS15190 -1.3 -4.0 5-(carboxyamino)imidazole ribonucleotide synthase compare
HGI48_RS10465 -1.3 -5.2 tryptophan synthase subunit beta compare
HGI48_RS17185 -1.3 -5.0 glycerol-3-phosphate 1-O-acyltransferase PlsY compare
HGI48_RS15510 -1.2 -2.4 type II secretion system pilot lipoprotein GspS compare
HGI48_RS09715 -1.2 -2.7 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE compare
HGI48_RS08300 -1.2 -2.9 CcdB family protein compare
HGI48_RS18195 -1.2 -3.9 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
HGI48_RS19425 -1.2 -2.1 sulfurtransferase complex subunit TusB compare
HGI48_RS21720 -1.2 -2.4 membrane protein insertion efficiency factor YidD compare
HGI48_RS02290 -1.2 -2.5 hypothetical protein compare
HGI48_RS08355 -1.2 -2.5 IS481 family transposase compare
HGI48_RS14405 -1.2 -7.9 amidophosphoribosyltransferase compare
HGI48_RS08645 -1.2 -6.3 NAD-dependent malic enzyme compare
HGI48_RS09730 -1.1 -3.3 imidazole glycerol phosphate synthase subunit HisH compare
HGI48_RS07115 -1.1 -1.4 EexN family lipoprotein compare
HGI48_RS06495 -1.1 -4.9 succinate dehydrogenase iron-sulfur subunit compare
HGI48_RS06120 -1.1 -4.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
HGI48_RS04795 -1.1 -2.7 hypothetical protein compare
HGI48_RS14035 -1.1 -1.3 LD-carboxypeptidase compare
HGI48_RS01150 -1.1 -3.2 thiazole synthase compare
HGI48_RS14680 -1.1 -1.7 membrane protein YpdK compare
HGI48_RS11530 -1.1 -1.9 tRNA 2-thiouridine(34) synthase MnmA compare
HGI48_RS11235 -1.1 -2.2 YcgL domain-containing protein compare
HGI48_RS02300 -1.0 -2.3 type VI secretion system tube protein Hcp compare
HGI48_RS10245 -1.0 -1.8 GlsB/YeaQ/YmgE family stress response membrane protein compare
HGI48_RS00795 -1.0 -1.5 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
HGI48_RS12925 -1.0 -4.7 quinone-dependent dihydroorotate dehydrogenase compare
HGI48_RS19690 -1.0 -1.3 DUF2531 family protein compare
HGI48_RS10200 -1.0 -3.6 non-heme ferritin compare
HGI48_RS19745 -1.0 -3.5 two-component system sensor histidine kinase EnvZ compare
HGI48_RS21640 -1.0 -2.6 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
HGI48_RS19750 -1.0 -2.4 two-component system response regulator OmpR compare
HGI48_RS20220 -0.9 -2.4 thioredoxin TrxA compare
HGI48_RS14445 -0.9 -1.5 4-phosphoerythronate dehydrogenase PdxB compare
HGI48_RS00265 -0.9 -2.4 mannitol-1-phosphate 5-dehydrogenase compare
HGI48_RS09835 -0.9 -3.5 DUF496 family protein compare
HGI48_RS21230 -0.9 -4.5 nitrogen regulation protein NR(II) compare
HGI48_RS06085 -0.9 -2.2 DnaA inactivator Hda compare
HGI48_RS02790 -0.9 -3.0 transcriptional regulator ExuR compare
HGI48_RS10425 -0.9 -1.2 YciI family protein compare
HGI48_RS14435 -0.9 -1.3 tRNA pseudouridine(38-40) synthase TruA compare
HGI48_RS12330 -0.9 -3.4 acid resistance repetitive basic protein Asr compare
HGI48_RS07145 -0.9 -2.4 hypothetical protein compare
HGI48_RS01050 -0.9 -1.4 tRNA-Thr compare
HGI48_RS12495 -0.9 -2.3 phage shock protein PspA compare
HGI48_RS10990 -0.9 -2.0 AAA family ATPase compare
HGI48_RS01515 -0.9 -5.6 outer membrane-stress sensor serine endopeptidase DegS compare
HGI48_RS12630 -0.9 -1.3 pyridoxamine 5'-phosphate oxidase compare
HGI48_RS16945 -0.9 -1.9 RNA polymerase sigma factor RpoS compare
HGI48_RS13780 -0.9 -3.1 LysE family transporter compare
HGI48_RS04450 -0.9 -2.4 cysteine synthase A compare
HGI48_RS15170 -0.9 -2.2 DoxX family protein compare
HGI48_RS07570 -0.9 -1.9 iron ABC transporter permease compare
HGI48_RS16355 -0.9 -1.7 recombinase RecA compare
HGI48_RS01650 -0.9 -4.7 3',5'-cyclic-AMP phosphodiesterase compare
HGI48_RS15535 -0.9 -5.0 IMP dehydrogenase compare
HGI48_RS18845 -0.9 -1.3 nitrogen fixation protein NifW compare
HGI48_RS11245 -0.9 -3.4 septum site-determining protein MinD compare
HGI48_RS07715 -0.9 -4.5 DUF2076 domain-containing protein compare
HGI48_RS20450 -0.9 -2.4 cell division protein FtsN compare
HGI48_RS04435 -0.9 -1.7 PTS glucose transporter subunit IIA compare
HGI48_RS11240 -0.8 -2.3 septum site-determining protein MinC compare
HGI48_RS02165 -0.8 -3.4 type-1Ba cytolytic delta-endotoxin compare
HGI48_RS04315 -0.8 -3.1 outer membrane protein assembly factor BamE compare
HGI48_RS09460 -0.8 -1.4 glutaredoxin, GrxA family compare
HGI48_RS00125 -0.8 -2.0 DUF3861 domain-containing protein compare
HGI48_RS17030 -0.8 -2.2 6-carboxytetrahydropterin synthase QueD compare
HGI48_RS07525 -0.8 -2.2 diaminobutyrate--2-oxoglutarate transaminase compare
HGI48_RS16230 -0.8 -4.4 polyphenol oxidase compare
HGI48_RS07065 -0.8 -3.7 SIR2 family protein compare
HGI48_RS06830 -0.8 -2.7 GalU regulator GalF compare
HGI48_RS20745 -0.8 -2.3 cell division protein FtsX compare
HGI48_RS06490 -0.8 -3.3 succinate dehydrogenase flavoprotein subunit compare
HGI48_RS21655 -0.8 -1.2 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
HGI48_RS15730 -0.8 -3.8 nitrogen regulatory protein P-II compare
HGI48_RS11490 -0.8 -3.1 DNA-binding transcriptional regulator KdgR compare
HGI48_RS12020 -0.8 -1.9 LysR family transcriptional regulator compare
HGI48_RS12960 -0.8 -1.7 nicotinate phosphoribosyltransferase compare
HGI48_RS13535 -0.8 -2.5 anti-sigma-28 factor FlgM compare
HGI48_RS06480 -0.8 -1.7 succinate dehydrogenase cytochrome b556 subunit compare
HGI48_RS14165 -0.7 -2.9 glutamine amidotransferase compare
HGI48_RS05200 -0.7 -1.7 VOC family protein compare
HGI48_RS13110 -0.7 -1.9 alpha/beta hydrolase compare
HGI48_RS14180 -0.7 -2.5 hydrogenase expression/formation protein HypE compare
HGI48_RS13235 -0.7 -3.4 dihydroorotase compare
HGI48_RS05260 -0.7 -0.9 transposase compare
HGI48_RS17210 -0.7 -4.0 translocation/assembly module TamB compare
HGI48_RS06400 -0.7 -4.8 alpha-D-glucose phosphate-specific phosphoglucomutase compare
HGI48_RS16320 -0.7 -1.4 tRNA-Arg compare
HGI48_RS12055 -0.7 -2.0 carboxy terminal-processing peptidase compare
HGI48_RS09210 -0.7 -1.2 hypothetical protein compare
HGI48_RS16175 -0.7 -4.8 methyltransferase domain-containing protein compare
HGI48_RS16190 -0.7 -3.8 endonuclease/exonuclease/phosphatase family protein compare
HGI48_RS00785 -0.7 -1.2 rhodanese-like domain-containing protein compare
HGI48_RS06005 -0.7 -1.9 SDR family oxidoreductase compare
HGI48_RS12580 -0.7 -3.4 orotidine-5'-phosphate decarboxylase compare
HGI48_RS19900 -0.7 -2.1 gluconate operon transcriptional repressor GntR compare
HGI48_RS06015 -0.7 -1.9 ABC transporter ATP-binding protein compare
HGI48_RS16995 -0.7 -3.5 sulfate adenylyltransferase subunit CysD compare
HGI48_RS12355 -0.7 -2.1 LUD domain-containing protein compare
HGI48_RS11915 -0.7 -3.7 methionine synthase compare
HGI48_RS01290 -0.7 -1.4 DNA-binding transcriptional regulator Fis compare
HGI48_RS10520 -0.7 -1.6 hypothetical protein compare
HGI48_RS07480 -0.7 -2.6 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase compare
HGI48_RS11215 -0.7 -1.5 hypothetical protein compare
HGI48_RS02940 -0.7 -2.2 phosphoadenosine phosphosulfate reductase family protein compare
HGI48_RS06925 -0.7 -2.9 D-galactonate utilization transcriptional regulator DgoR compare
HGI48_RS11545 -0.7 -2.2 two-component system response regulator PhoP compare
HGI48_RS14545 -0.7 -3.2 phosphohistidine phosphatase SixA compare
HGI48_RS20780 -0.7 -1.3 sulfurtransferase TusA compare
HGI48_RS15830 -0.7 -3.2 elongation factor 4 compare
HGI48_RS20475 -0.7 -2.2 cell division protein ZapB compare
HGI48_RS12545 -0.7 -3.2 exoribonuclease II compare
HGI48_RS12210 -0.7 -1.9 phage tail assembly protein compare
HGI48_RS03695 -0.7 -3.3 glycoside hydrolase 43 family protein compare
HGI48_RS08185 -0.7 -2.7 NAD(P)H-dependent oxidoreductase compare
HGI48_RS09220 -0.7 -3.6 ABC transporter permease subunit compare
HGI48_RS04395 -0.7 -2.5 Dyp-type peroxidase compare
HGI48_RS10235 -0.6 -1.5 YebY family protein compare
HGI48_RS20270 -0.6 -3.7 ketol-acid reductoisomerase compare
HGI48_RS04775 -0.6 -2.4 nucleotidyltransferase family protein compare
HGI48_RS00680 -0.6 -1.5 orotate phosphoribosyltransferase compare
HGI48_RS10035 -0.6 -1.4 hypothetical protein compare
HGI48_RS14110 -0.6 -2.2 nitrate- and nitrite sensing domain-containing protein compare
HGI48_RS06900 -0.6 -2.3 ABC transporter permease compare
HGI48_RS09745 -0.6 -1.8 histidinol dehydrogenase compare
HGI48_RS20880 -0.6 -1.6 hypothetical protein compare
HGI48_RS11905 -0.6 -1.5 transposase compare
HGI48_RS03685 -0.6 -1.3 GNAT family N-acetyltransferase compare
HGI48_RS01210 -0.6 -3.4 phosphoribosylamine--glycine ligase compare
HGI48_RS11300 -0.6 -3.5 L-serine ammonia-lyase compare
HGI48_RS18110 -0.6 -0.7 thiamine ABC transporter ATP-binding protein ThiQ compare
HGI48_RS04820 -0.6 -2.1 type II toxin-antitoxin system toxin CcdB compare
HGI48_RS13755 -0.6 -1.1 acyl carrier protein compare
HGI48_RS09760 -0.6 -2.5 SDR family oxidoreductase compare
HGI48_RS18805 -0.6 -2.1 hypothetical protein compare
HGI48_RS20045 -0.6 -2.3 tyrosine recombinase XerC compare
HGI48_RS21610 -0.6 -2.3 4'-phosphopantetheinyl transferase compare
HGI48_RS16060 -0.6 -3.0 polynucleotide adenylyltransferase PcnB compare
HGI48_RS04220 -0.6 -1.7 transposase compare
HGI48_RS18075 -0.6 -0.9 siderophore-interacting protein compare
HGI48_RS01435 -0.6 -2.1 PTS IIA-like nitrogen regulatory protein PtsN compare
HGI48_RS08900 -0.6 -1.8 outer membrane protein OmpX compare
HGI48_RS04080 -0.6 -1.3 type II toxin-antitoxin system RelB/DinJ family antitoxin compare
HGI48_RS05675 -0.6 -2.0 transcriptional regulator BolA compare
HGI48_RS07600 -0.6 -1.4 type II toxin-antitoxin system RelE/ParE family toxin compare
HGI48_RS15930 -0.6 -0.8 TSUP family transporter compare
HGI48_RS14315 -0.6 -2.8 transcriptional regulator LrhA compare
HGI48_RS05895 -0.6 -0.9 Cu(I)-responsive transcriptional regulator compare
HGI48_RS15275 -0.6 -1.5 heat shock protein HspQ compare
HGI48_RS00620 -0.6 -1.8 isoaspartyl peptidase/L-asparaginase compare
HGI48_RS20400 -0.6 -2.2 Si-specific NAD(P)(+) transhydrogenase compare
HGI48_RS16985 -0.6 -1.4 adenylyl-sulfate kinase compare
HGI48_RS00960 -0.6 -1.1 YeeE/YedE family protein compare
HGI48_RS05455 -0.6 -1.3 pyrimidine/purine nucleoside phosphorylase compare
HGI48_RS03450 -0.6 -2.1 single-stranded-DNA-specific exonuclease RecJ compare
HGI48_RS13295 -0.6 -2.9 MCP four helix bundle domain-containing protein compare
HGI48_RS05390 -0.6 -0.9 alkylphosphonate utilization protein compare
HGI48_RS01570 -0.6 -1.8 aerobic respiration two-component sensor histidine kinase ArcB compare
HGI48_RS03520 -0.6 -2.3 sugar transferase compare
HGI48_RS00775 -0.6 -1.2 divergent polysaccharide deacetylase family protein compare


Specific Phenotypes

None in this experiment

For Dickeya dianthicola 67-19 in control experiments

For control kanamycin across organisms