Experiment set9S547 for Escherichia coli BL21

Compare to:

CBA120

200 most detrimental genes:

  gene name fitness t score description  
ECD_01706 +1.5 4.0 N,N'-diacetylchitobiose-specific enzyme IIC component of PTS compare
ECD_01681 +1.1 1.7 integration host factor (IHF), DNA-binding protein, alpha subunit compare
ECD_01694 +1.0 2.8 fructosamine kinase family protein compare
ECD_02250 +1.0 1.8 uncharacterized protein compare
ECD_01241 +0.9 2.8 putative RNA binding protein compare
ECD_01230 +0.9 1.5 outer membrane protein W compare
ECD_00502 +0.9 2.1 DLP12 prophage; putative antitermination protein compare
ECD_00939 +0.9 3.5 alkanesulfonate monooxygenase, FMNH(2)-dependent compare
ECD_01792 +0.8 1.9 23S rRNA m(1)G745 methyltransferase, SAM-dependent compare
ECD_02070 +0.8 2.8 UPF0299 family inner membrane protein compare
ECD_02840 +0.8 1.7 secretin (GspDbeta) OM localization lipoprotein pilotin compare
ECD_00407 +0.8 1.0 DUF1428 family protein compare
ECD_04212 +0.8 2.5 5-methylcytosine-specific restriction enzyme McrBC, subunit McrB compare
ECD_00967 +0.8 2.3 methylglyoxal synthase compare
ECD_01405 +0.8 1.8 methionine N-acyltransferase; L-amino acid N-acyltransferase compare
ECD_02175 +0.8 2.3 inactive PncC family protein compare
ECD_01200 +0.7 3.5 sensory histidine kinase in two-component regulatory system with NarL compare
ECD_01852 +0.7 1.6 chemotaxis regulator, protein phosphatase for CheY compare
ECD_00500 +0.7 2.0 DLP12 prophage; endonuclease RUS compare
ECD_00487 +0.7 1.7 Excisionase compare
ECD_01375 +0.7 1.8 putative periplasmic protein compare
ECD_02431 +0.7 3.1 3-phenylpropionate dioxygenase, small (beta) subunit compare
ECD_00848 +0.7 1.4 bacteriophage tail fiber protein compare
ECD_03425 +0.7 1.8 putative hydrogenase, 4Fe-4S ferredoxin-type component compare
ECD_01399 +0.7 1.4 putative ABC transporter permease compare
ECD_02365 +0.7 1.8 palmitoyl-CoA esterase activity, uncertain physiological substrate compare
ECD_03696 +0.7 1.2 DUF2628 family putative inner membrane protein compare
ECD_00969 +0.7 1.7 putative CoA-binding protein compare
ECD_03766 +0.6 2.1 6-deoxy-6-sulfofructose-1-phosphate aldolase compare
ECD_01634 +0.6 2.4 multidrug efflux system transporter compare
ECD_01240 +0.6 2.1 PHP domain protein compare
ECD_02972 +0.6 2.1 DUF805 family inner membrane protein compare
ECD_01042 +0.6 1.8 O-acetyl-ADP-ribose deacetylase; RNase III inhibitor during cold shock; putative cardiolipin synthase C regulatory subunit compare
ECD_00494 +0.6 1.6 DLP12 prophage; putative recombinase compare
ECD_01667 +0.6 1.2 putative electron transfer flavoprotein, FAD-binding subunit compare
ECD_01696 +0.6 1.5 2-deoxyglucose-6-P phosphatase compare
ECD_00801 +0.6 1.6 putative membrane-anchored diguanylate cyclase compare
ECD_00955 +0.6 1.5 paraquat-inducible, SoxRS-regulated MCE domain protein compare
ECD_01302 +0.6 1.5 L-Ala-D/L-Glu epimerase compare
ECD_01556 +0.6 1.0 putative selenate reductase, periplasmic compare
ECD_01925 +0.6 1.7 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
ECD_03207 +0.6 1.6 OsmC family protein compare
ECD_01854 +0.5 2.4 fused chemotaxis regulator: protein-glutamate methylesterase in two-component regulatory system with CheA compare
ECD_01166 +0.5 2.3 putative cation/proton antiporter compare
ECD_00835 +0.5 1.6 hypothetical protein compare
ECD_00596 +0.5 1.4 TatABCE protein translocation system subunit compare
ECD_01565 +0.5 0.7 putative arabinose efflux transporter compare
ECD_01842 +0.5 1.2 tRNA (cmo5U34)-carboxymethyltransferase, carboxy-SAM-dependent compare
ECD_00858 +0.5 1.3 negative regulator of motility; multicopy suppressor of coaA(Ts) compare
ECD_01168 +0.5 1.1 lytic murein endotransglycosylase E compare
ECD_02135 +0.5 2.0 ferredoxin-type protein, role in electron transfer to periplasmic nitrate reductase NapA compare
ECD_01816 +0.5 2.7 protease II compare
ECD_01770 +0.5 1.6 D-malate oxidase, NAD-dependent; putative tartrate dehydrogenase compare
ECD_00188 +0.5 2.1 UPF0253 family protein compare
ECD_04270 +0.5 1.5 non-canonical purine NTP phosphatase, ITPase/XTPase compare
ECD_01248 +0.5 1.8 inner membrane protein, S49 peptidase family protein compare
ECD_00695 +0.5 1.6 putative inner membrane protein in cydABX-ybgE operon compare
ECD_01288 +0.5 1.3 putative sugar ABC transporter permease compare
ECD_02147 +0.5 1.6 fused response regulator of ato operon, in two-component system with AtoS: response regulator/sigma54 interaction protein compare
ECD_00455 +0.5 1.6 ureidoglycolate lyase, releasing urea compare
ECD_01167 +0.5 0.8 murein tetrapeptide carboxypeptidase; LD-carboxypeptidase A compare
ECD_02192 +0.5 1.9 isochorismate synthase 2 compare
ECD_00082 +0.5 1.4 RsmH methytransferase inhibitor compare
ECD_03530 +0.5 1.0 hypothetical protein compare
ECD_01624 +0.5 1.2 glutaredoxin-4 compare
ECD_04391 +0.5 1.5 hypothetical protein compare
ECD_01872 +0.5 1.0 lipoprotein, function unknown compare
ECD_02028 +0.5 1.2 putative kinase compare
ECD_02909 +0.5 1.6 DUF1190 family protein compare
ECD_02093 +0.5 1.8 putative nucleoside transporter compare
ECD_00450 +0.5 0.6 conserved protein, rhs-like protein compare
ECD_02477 +0.5 1.0 DTW domain protein compare
ECD_02131 +0.5 2.3 ferredoxin-type protein compare
ECD_01970 +0.5 1.7 suppressor of OmpF assembly mutants; putative outer membrane protein assembly factor; inner membrane-anchored periplasmic protein compare
ECD_03798 +0.5 1.2 response regulator in two-component regulatory system with CpxA compare
ECD_01300 +0.5 1.6 aromatic amino acid biosynthesis and transport regulon transcriptional regulator; autorepressor; ATPase; phosphatase compare
ECD_02071 +0.5 2.3 LrgB family inner membrane protein compare
ECD_00453 +0.4 2.4 tRNA 2-selenouridine synthase, selenophosphate-dependent compare
ECD_00594 +0.4 1.0 fluoride efflux channel, dual topology membrane protein compare
ECD_00849 +0.4 1.3 putative DNA-invertase compare
ECD_00315 +0.4 2.4 taurine ABC transporter periplasmic binding protein compare
ECD_02124 +0.4 1.0 periplasmic heme chaperone compare
ECD_01349 +0.4 1.5 pyruvate-flavodoxin oxidoreductase compare
ECD_00139 +0.4 1.8 putative periplasmic pilin chaperone compare
ECD_03997 +0.4 1.5 putative 4Fe-4S mono-cluster protein compare
ECD_01198 +0.4 0.8 putative invasin compare
ECD_02320 +0.4 1.2 WGR domain protein compare
ECD_02018 +0.4 2.2 galactitol-specific enzyme IIC component of PTS compare
ECD_00228 +0.4 1.8 mRNA interferase toxin of the YafO-YafN toxin-antitoxin system compare
ECD_01635 +0.4 1.6 autotransporter adhesin-related protein compare
ECD_01314 +0.4 1.9 p-aminobenzoyl-glutamate hydrolase, B subunit compare
ECD_00317 +0.4 1.9 taurine ABC transporter permease compare
ECD_02258 +0.4 1.2 putative fimbrial-like adhesin protein compare
ECD_00774 +0.4 1.1 23S rRNA m(6)A1618 methyltransferase, SAM-dependent compare
ECD_02389 +0.4 2.7 uracil permease compare
ECD_01921 +0.4 1.2 ATP phosphoribosyltransferase compare
ECD_00273 +0.4 1.6 putative inner membrane protein compare
ECD_00471 +0.4 1.6 putative carbonate kinase compare
ECD_01478 +0.4 1.1 altronate oxidoreductase, NAD-dependent compare
ECD_01972 +0.4 1.2 uridine/cytidine kinase compare
ECD_01238 +0.4 1.9 component I of anthranilate synthase compare
ECD_02335 +0.4 2.0 N-acetylmuramoyl-l-alanine amidase I compare
ECD_03591 +0.4 1.3 tryptophanase leader peptide compare
ECD_04071 +0.4 2.0 Hexuronate transporter compare
ECD_01031 +0.4 1.5 alkaline phosphatase compare
ECD_01915 +0.4 1.5 putative TusA family sulfurtransferase compare
ECD_01104 +0.4 0.6 putative UPF0227 family esterase compare
ECD_04309 +0.4 0.8 uncharacterized protein compare
ECD_01604 +0.4 1.3 dipeptide and tripeptide permease A compare
ECD_00988 +0.4 1.7 putative O-antigen capsule production periplasmic protein compare
ECD_01735 +0.4 0.9 protease IV (signal peptide peptidase) compare
ECD_02400 +0.4 1.8 IMP dehydrogenase compare
ECD_01879 +0.4 0.8 response regulator in two-component regulatory system with BarA compare
ECD_01561 +0.4 1.1 H(+)/Cl(-) exchange transporter compare
ECD_00865 +0.4 1.2 arginine ABC transporter periplasmic binding protein compare
ECD_02351 +0.4 1.0 RmlC-like cupin domain protein compare
ECD_02280 +0.4 1.2 hybrid sensory histidine kinase in two-component regulatory system with EvgA compare
ECD_00490 +0.4 1.2 putative DNA N-6-adenine-methyltransferase of bacteriophage compare
ECD_00233 +0.4 1.8 xanthine phosphoribosyltransferase; xanthine-guanine phosphoribosyltransferase compare
ECD_01292 +0.4 1.8 putative NADH-binding oxidoreductase compare
ECD_01305 +0.4 1.5 S9-like protein non-peptidase family protein compare
ECD_01736 +0.4 1.0 cytoplasmic L-asparaginase 1 compare
ECD_03001 +0.4 0.6 putative phosphotransferase system enzyme subunit (N-acetyl-galactosamine/galactosamine PTS system enzyme IIA component) compare
ECD_04159 +0.4 1.9 RNA polymerase sigma-19 factor, fec operon-specific; ECF sigma factor compare
ECD_04198 +0.4 1.8 SpmB family inner membrane protein compare
ECD_04147 +0.4 1.5 hypothetical protein compare
ECD_01487 +0.4 1.4 phage N15 gp48-like protein compare
ECD_01374 +0.4 1.8 cytochrome b561 compare
ECD_02901 +0.4 1.3 quinol monooxygenase compare
ECD_02065 +0.4 1.8 Yip1 family inner membrane protein compare
ECD_03358 +0.4 0.6 stress response protein acid-resistance protein compare
ECD_00499 +0.4 1.1 DLP12 prophage; uncharacterized protein compare
ECD_01896 +0.4 0.7 putative multdrug exporter, MATE family compare
ECD_01014 +0.4 1.5 ureidoacrylate amidohydrolase compare
ECD_00968 +0.4 1.6 UPF0319 family protein compare
ECD_03817 +0.4 1.5 peptidase component of the HslUV protease compare
ECD_01289 +0.4 1.4 putative sugar ABC transporter permease compare
ECD_01067 +0.4 0.9 anti-sigma factor for FliA (sigma 28) compare
ECD_00857 +0.4 1.4 ribosomal protein S6 modification protein compare
ECD_02396 +0.4 1.7 uncharacterized protein compare
ECD_00844 +0.4 1.3 putative phage tail protein compare
ECD_01408 +0.4 1.2 putative iron outer membrane transporter compare
ECD_00292 +0.4 1.2 transcriptional activator of cyn operon; autorepressor compare
ECD_00238 +0.4 1.5 outer membrane phosphoporin protein E compare
ECD_02459 +0.4 0.5 gap repair protein compare
ECD_00779 +0.4 1.1 Fe-binding and storage protein; stress-inducible DNA-binding protein compare
ECD_01649 +0.4 0.8 cysteine desulfurase, stimulated by SufE; selenocysteine lyase, PLP-dependent compare
ECD_03623 +0.4 1.3 ATP synthase, membrane-bound accessory factor compare
ECD_01018 +0.4 1.1 proline:sodium symporter compare
ECD_00777 +0.4 1.4 glutamine transporter subunit compare
ECD_00441 +0.4 1.0 iron export ABC transporter ATPase; peroxide resistance protein compare
ECD_01733 +0.3 1.6 selenophosphate synthase compare
ECD_01022 +0.3 1.2 ATP-binding protein; putative PhoH family P-loop ATPase compare
ECD_01671 +0.3 1.8 phosphoenolpyruvate synthase compare
ECD_00161 +0.3 1.7 carbohydrate diacid regulon transcriptional regulator; autoregulator compare
ECD_00192 +0.3 1.1 putative lipoprotein compare
ECD_02968 +0.3 1.8 DUF1469 family inner membrane protein compare
ECD_02336 +0.3 1.8 coproporphyrinogen III oxidase compare
ECD_03950 +0.3 1.9 Sel1 family TPR-like repeat protein compare
ECD_03217 +0.3 1.0 nitrite reductase (NADH) small subunit compare
ECD_00834 +0.3 0.9 putative capsid scaffolding protein compare
ECD_01923 +0.3 1.7 histidinol-phosphate aminotransferase compare
ECD_02127 +0.3 0.8 heme export ABC transporter permease compare
ECD_02308 +0.3 0.9 transcriptional regulator of yefH compare
ECD_00956 +0.3 0.6 DUF330 family putative lipoprotein compare
ECD_t00059 +0.3 0.6 tRNA-Thr compare
ECD_01459 +0.3 1.4 putative oxidoreductase compare
ECD_02783 +0.3 1.5 UPF0235 family protein compare
ECD_02083 +0.3 1.7 S-formylglutathione hydrolase compare
ECD_01976 +0.3 1.8 protein kinase-related putative non-specific DNA-binding protein compare
ECD_02080 +0.3 0.9 galactose- and fucose-inducible galactose regulon transcriptional isorepressor; mgl operon transcriptional repressor; autorepressor compare
ECD_02345 +0.3 0.6 ethanolamine utilization protein, HSP70/actin superfamily protein compare
ECD_00367 +0.3 1.5 2-carboxybenzaldehyde reductase compare
ECD_03405 +0.3 1.3 HTH_CROC1 family putative transcriptional regulator compare
ECD_01866 +0.3 1.3 trehalose-6-phosphate phosphatase, biosynthetic compare
ECD_02373 +0.3 0.5 hydrogenase 4, 4Fe-4S subunit compare
ECD_00704 +0.3 0.9 nicotinamide riboside transporter compare
ECD_02305 +0.3 1.0 DUF1323 family putative DNA-binding protein compare
ECD_01009 +0.3 1.8 pyrimidine permease compare
ECD_01083 +0.3 1.8 m(7)GTP pyrophosphatase compare
ECD_02380 +0.3 1.0 hydrogenase 4, Fe-S subunit compare
ECD_04156 +0.3 1.5 ferric citrate ABC transporter periplasmic binding protein compare
ECD_00464 +0.3 1.1 glycerate kinase II compare
ECD_01388 +0.3 0.6 lipoprotein compare
ECD_02054 +0.3 0.6 putative response regulator in two-component system withYehU compare
ECD_04024 +0.3 0.7 fumarate reductase (anaerobic), membrane anchor subunit compare
ECD_00028 +0.3 1.8 uncharacterized protein compare
ECD_00782 +0.3 1.6 OPG biosynthetic transmembrane phosphoethanolamine transferase compare
ECD_03213 +0.3 0.8 putative antitoxin for Fic compare
ECD_00708 +0.3 0.9 phosphoglyceromutase 1 compare
ECD_04274 +0.3 1.5 response regulator in two-component regulatory system with CreC compare
ECD_03232 +0.3 1.5 phosphopentomutase-related metalloenzyme superfamily protein compare
ECD_00377 +0.3 0.6 putative acetyltransferase compare
ECD_03554 +0.3 1.3 acetolactate synthase 1 small subunit compare
ECD_02100 +0.3 1.2 UPF0153 cysteine cluster protein compare
ECD_03577 +0.3 2.2 2-oxo-3-deoxygalactonate kinase compare
ECD_01148 +0.3 1.3 hypothetical protein compare
ECD_04160 +0.3 1.4 IS1 protein InsA compare
ECD_01632 +0.3 1.1 cyclopropane fatty acyl phospholipid synthase, SAM-dependent compare
ECD_01006 +0.3 0.5 uncharacterized protein compare


Specific Phenotypes

None in this experiment

For Escherichia coli BL21 in phage experiments

For phage MOI 10 across organisms