Experiment set9S481 for Escherichia coli BL21

Compare to:

Bas18

200 most detrimental genes:

  gene name fitness t score description  
ECD_00196 +1.9 9.6 DL-methionine transporter subunit compare
ECD_03659 +1.3 2.5 thioredoxin 1 compare
ECD_03486 +1.2 5.1 UDP-glucose:(Glucosyl) LPS alpha1,3-glucosyltransferase WaaO compare
ECD_03144 +1.1 1.8 DUF1992 family protein compare
ECD_t00019 +1.1 2.0 tRNA-Lys compare
ECD_02607 +1.0 1.8 phosphoadenosine phosphosulfate reductase; PAPS reductase, thioredoxin dependent compare
ECD_01045 +1.0 2.5 OPG biosynthetic periplasmic beta-1,6 branching glycosyltransferase compare
ECD_04212 +1.0 2.3 5-methylcytosine-specific restriction enzyme McrBC, subunit McrB compare
ECD_01472 +0.9 2.1 autoinducer 2 import system permease protein compare
ECD_01629 +0.9 2.6 transcriptional repressor, hypoxanthine-binding compare
ECD_02284 +0.9 1.1 formyl-CoA transferase, NAD(P)-binding compare
ECD_01230 +0.9 1.1 outer membrane protein W compare
ECD_04119 +0.9 1.7 SopA-central-domain-like hexapeptide repeat protein compare
ECD_01109 +0.9 2.3 L,D-transpeptidase linking Lpp to murein compare
ECD_01221 +0.9 2.8 oligopeptide ABC transporter ATPase compare
ECD_01405 +0.9 1.3 methionine N-acyltransferase; L-amino acid N-acyltransferase compare
ECD_01022 +0.8 3.1 ATP-binding protein; putative PhoH family P-loop ATPase compare
ECD_02076 +0.8 2.1 dihydropyrimidine dehydrogenase, NADH-dependent, subunit C compare
ECD_01947 +0.8 3.2 dTDP-glucose 4,6 dehydratase, NAD(P)-binding compare
ECD_01452 +0.8 1.9 putative periplasmic M16 family zinc metalloendopeptidase compare
ECD_03660 +0.8 0.7 rho operon leader peptide compare
ECD_00941 +0.8 2.2 NAD(P)H-dependent FMN reductase compare
ECD_02250 +0.8 1.3 uncharacterized protein compare
ECD_02147 +0.8 1.8 fused response regulator of ato operon, in two-component system with AtoS: response regulator/sigma54 interaction protein compare
ECD_02840 +0.7 1.4 secretin (GspDbeta) OM localization lipoprotein pilotin compare
ECD_00532 +0.7 1.9 response regulator in two-component regulatory system with CusS compare
ECD_02091 +0.7 1.8 ribonucleoside hydrolase 2 compare
ECD_00439 +0.7 1.6 inner membrane protein; stimulator of the QmcA suppressor of ftsH-htpX compare
ECD_00612 +0.7 1.9 DUF1451 family protein compare
ECD_01733 +0.7 1.7 selenophosphate synthase compare
ECD_02224 +0.7 3.1 putative NUDIX hydrolase compare
ECD_04194 +0.7 2.0 uncharacterized protein compare
ECD_01910 +0.7 1.9 UPF0265 family protein compare
ECD_00986 +0.7 2.1 putative O-antigen capsule outer membrane auxillary protein export channel compare
ECD_00176 +0.7 1.1 periplasmic chaperone compare
ECD_03339 +0.7 3.1 hypothetical protein compare
ECD_01925 +0.7 1.8 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
ECD_02127 +0.7 2.6 heme export ABC transporter permease compare
ECD_02820 +0.6 1.1 hypothetical protein compare
ECD_01752 +0.6 1.9 protein kinase, endogenous substrate unidentified; autokinase compare
ECD_00483 +0.6 2.1 FimA-like protein compare
ECD_02028 +0.6 1.3 putative kinase compare
ECD_03132 +0.6 1.2 dehydroshikimate reductase, NAD(P)-binding compare
ECD_00481 +0.6 0.8 putative periplasmic pilus chaperone compare
ECD_01012 +0.6 1.1 putative reactive intermediate detoxifying aminoacrylate hydrolase compare
ECD_01586 +0.6 1.4 beta-D-glucuronidase compare
ECD_01792 +0.6 1.1 23S rRNA m(1)G745 methyltransferase, SAM-dependent compare
ECD_01003 +0.6 1.5 DnaK co-chaperone; curved DNA-binding protein compare
ECD_02291 +0.6 2.1 response regulator activating yhjX; pyruvate-responsive YpdAB two-component system compare
ECD_02432 +0.6 1.0 3-phenylpropionate dioxygenase, ferredoxin subunit compare
ECD_00376 +0.6 1.8 hypothetical protein compare
ECD_04146 +0.6 2.5 IS911 orfA-like protein compare
ECD_01706 +0.6 0.9 N,N'-diacetylchitobiose-specific enzyme IIC component of PTS compare
ECD_02333 +0.6 1.9 inner membrane protein compare
ECD_01985 +0.6 0.9 UPF0339 family protein compare
ECD_02732 +0.6 1.4 UPF0267 family protein compare
ECD_01876 +0.6 1.4 UPF0149 family protein compare
ECD_02204 +0.5 0.9 NADH:ubiquinone oxidoreductase, membrane subunit K compare
ECD_02447 +0.5 3.0 putative outer membrane protein modulating the QseEF response compare
ECD_01551 +0.5 0.9 UPF0060 family inner membrane protein compare
ECD_00813 +0.5 0.5 transcriptional regulator of csgD and ybiJI; autoregulator compare
ECD_00744 +0.5 2.0 malonyl-ACP O-methyltransferase, SAM-dependent compare
ECD_04185 +0.5 0.7 periplasmic chaperone compare
ECD_00417 +0.5 1.6 DUF2496 family protein compare
ECD_00771 +0.5 1.8 Fe(II)-dependent oxygenase superfamily protein compare
ECD_02377 +0.5 0.7 hydrogenase 4, membrane subunit compare
ECD_02826 +0.5 0.9 hypothetical protein compare
ECD_02153 +0.5 3.1 tandem DUF2300 domain protein, putative host defense protein compare
ECD_02833 +0.5 1.3 putative type II secretion protein GspI compare
ECD_01441 +0.5 1.1 D,D-dipeptide ABC transporter ATPase compare
ECD_02852 +0.5 2.4 hypothetical protein compare
ECD_00848 +0.5 1.2 bacteriophage tail fiber protein compare
ECD_00847 +0.5 2.2 e14 prophage; putative tail fiber assembly protein compare
ECD_00858 +0.5 1.3 negative regulator of motility; multicopy suppressor of coaA(Ts) compare
ECD_01838 +0.5 2.1 isochorismatase family protein compare
ECD_01238 +0.5 2.2 component I of anthranilate synthase compare
ECD_00962 +0.5 3.5 SOS cell division inhibitor compare
ECD_00082 +0.5 1.0 RsmH methytransferase inhibitor compare
ECD_02054 +0.5 1.3 putative response regulator in two-component system withYehU compare
ECD_00859 +0.5 1.6 putrescine ABC transporter periplasmic binding protein compare
ECD_00407 +0.5 0.5 DUF1428 family protein compare
ECD_02113 +0.5 1.6 16S rRNA pseudouridine(516) synthase compare
ECD_01275 +0.5 1.4 gamma-glutamyl-gamma-aminobutyrate hydrolase compare
ECD_01666 +0.5 1.2 putative electron transfer flavoprotein subunit compare
ECD_04274 +0.5 2.4 response regulator in two-component regulatory system with CreC compare
ECD_01700 +0.5 1.0 cell division modulator compare
ECD_04049 +0.5 1.1 PspA/IM30 family protein compare
ECD_01879 +0.5 0.9 response regulator in two-component regulatory system with BarA compare
ECD_01621 +0.5 0.6 glyoxalase I, Ni-dependent compare
ECD_00849 +0.5 0.9 putative DNA-invertase compare
ECD_02172 +0.5 1.2 putative L-rhamnonate transporter compare
ECD_00865 +0.5 1.7 arginine ABC transporter periplasmic binding protein compare
ECD_01167 +0.5 0.8 murein tetrapeptide carboxypeptidase; LD-carboxypeptidase A compare
ECD_01692 +0.5 1.6 6-phosphofructokinase II compare
ECD_01816 +0.5 2.1 protease II compare
ECD_01399 +0.5 1.2 putative ABC transporter permease compare
ECD_00228 +0.5 1.3 mRNA interferase toxin of the YafO-YafN toxin-antitoxin system compare
ECD_02973 +0.5 1.0 DUF805 family inner membrane protein compare
ECD_00880 +0.5 0.9 aquaporin Z compare
ECD_02286 +0.5 0.8 putative lipoprotein involved in colanic acid biosynthesis compare
ECD_02829 +0.5 1.8 putative membrane-anchored secretion pathway M-type protein compare
ECD_00946 +0.5 1.5 putative fimbriae protein compare
ECD_02321 +0.5 0.9 cysteine synthase B (O-acetylserine sulfhydrolase B) compare
ECD_01624 +0.5 1.0 glutaredoxin-4 compare
ECD_00748 +0.5 1.1 molybdopterin biosynthesis protein A compare
ECD_00405 +0.5 1.1 outer membrane lipoprotein compare
ECD_01900 +0.5 1.8 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
ECD_00782 +0.5 2.2 OPG biosynthetic transmembrane phosphoethanolamine transferase compare
ECD_00999 +0.5 1.2 trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit compare
ECD_02176 +0.5 2.3 outer membrane protein, putative porin compare
ECD_01691 +0.5 0.6 acid-inducible putative outer membrane protein compare
ECD_01111 +0.5 1.3 inner membrane protein compare
ECD_01396 +0.4 0.7 putative DNA-binding transcriptional regulator and putative aminotransferase compare
ECD_00904 +0.4 1.1 LysR family putative transcriptional regulator compare
ECD_00695 +0.4 1.2 putative inner membrane protein in cydABX-ybgE operon compare
ECD_02713 +0.4 1.9 putative oxidoreductase compare
ECD_02825 +0.4 1.1 Pyrophosphorylase compare
ECD_02148 +0.4 1.6 acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit compare
ECD_01954 +0.4 0.9 phosphomannomutase compare
ECD_00988 +0.4 1.3 putative O-antigen capsule production periplasmic protein compare
ECD_02283 +0.4 1.1 oxalyl CoA decarboxylase, ThDP-dependent compare
ECD_04384 +0.4 0.9 small predicted membrane protein compare
ECD_00621 +0.4 2.0 glutamate/aspartate ABC transporter permease compare
ECD_01443 +0.4 1.2 D,D-dipeptide ABC transporter permease compare
ECD_00976 +0.4 2.1 hydrogenase 1, large subunit compare
ECD_03338 +0.4 1.3 DUF4049 family protein compare
ECD_01956 +0.4 1.0 putative glycosyl transferase compare
ECD_01195 +0.4 0.7 cation transport regulator compare
ECD_00380 +0.4 0.7 cytochrome o ubiquinol oxidase subunit IV compare
ECD_00808 +0.4 1.5 undecaprenyl pyrophosphate phosphatase compare
ECD_00792 +0.4 1.2 fructose-6-phosphate aldolase 1 compare
ECD_01749 +0.4 1.0 D-hexose-6-phosphate epimerase-like protein compare
ECD_04019 +0.4 1.1 entericidin B membrane lipoprotein compare
ECD_00982 +0.4 1.2 cytochrome bd-II oxidase, subunit II compare
ECD_00339 +0.4 1.1 hypothetical protein compare
ECD_02866 +0.4 1.9 hydrogenase 2 accessory protein compare
ECD_02415 +0.4 2.2 aminopeptidase B compare
ECD_03217 +0.4 1.2 nitrite reductase (NADH) small subunit compare
ECD_01915 +0.4 1.1 putative TusA family sulfurtransferase compare
ECD_00469 +0.4 1.7 hypothetical protein compare
ECD_01264 +0.4 1.6 putative oxidoreductase compare
ECD_02077 +0.4 1.1 methyl-galactoside transporter subunit compare
ECD_01215 +0.4 2.3 fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase compare
ECD_01789 +0.4 1.6 mannose-specific enzyme IID component of PTS compare
ECD_04267 +0.4 2.7 energy-dependent translational throttle A compare
ECD_01349 +0.4 1.0 pyruvate-flavodoxin oxidoreductase compare
ECD_02218 +0.4 1.6 sugar phosphatase compare
ECD_02494 +0.4 2.2 OM lipoprotein putative positive effector of YfiN activity compare
ECD_04346 +0.4 1.0 hypothetical protein compare
ECD_01785 +0.4 1.0 putative membrane-anchored cyclic-di-GMP phosphodiesterase, regulator of cellulose production compare
ECD_00749 +0.4 1.0 inactive molybdopterin adenylyltransferase compare
ECD_03001 +0.4 0.9 putative phosphotransferase system enzyme subunit (N-acetyl-galactosamine/galactosamine PTS system enzyme IIA component) compare
ECD_00956 +0.4 0.8 DUF330 family putative lipoprotein compare
ECD_00310 +0.4 2.1 alcohol dehydrogenase class III; glutathione-dependent formaldehyde dehydrogenase compare
ECD_00506 +0.4 1.0 DLP12 prophage; putative phage lysis protein compare
ECD_00998 +0.4 1.3 response regulator in two-component regulatory system with TorS compare
ECD_00484 +0.4 1.3 FimA-like protein compare
ECD_04293 +0.4 0.6 inhibitor of glucose uptake compare
ECD_04388 +0.4 1.2 putative membrane-bound BasS regulator compare
ECD_01313 +0.4 1.0 p-aminobenzoyl-glutamate transporter; membrane protein compare
ECD_03207 +0.4 1.1 OsmC family protein compare
ECD_02027 +0.4 1.0 ADP-ribosylglycohydrolase family protein compare
ECD_02584 +0.4 0.4 serine/threonine-specific protein phosphatase 2 compare
ECD_01844 +0.4 1.5 TMAO reductase III (TorYZ), cytochrome c-type subunit compare
ECD_01980 +0.4 1.3 multidrug efflux system, subunit B compare
ECD_00967 +0.4 1.2 methylglyoxal synthase compare
ECD_01059 +0.4 1.2 lipoprotein, DUF1439 family compare
ECD_01573 +0.4 1.2 DUF1471 family periplasmic protein compare
ECD_01281 +0.4 1.6 regulatory protein for phage-shock-protein operon compare
ECD_02477 +0.4 0.8 DTW domain protein compare
ECD_01211 +0.4 1.5 PcnB-degradosome interaction factor; response regulator compare
ECD_02034 +0.4 0.8 hypothetical protein compare
ECD_00347 +0.4 2.1 response regulator in two-component regulatory system with PhoR compare
ECD_02155 +0.4 0.7 DUF1175 family protein, putative host defense protein compare
ECD_00838 +0.4 1.0 putative phage tail protein compare
ECD_02210 +0.4 1.1 NADH:ubiquinone oxidoreductase, chain E compare
ECD_03998 +0.4 1.1 GNAT family putative N-acetyltransferase compare
ECD_00358 +0.4 1.4 HNH nuclease family protein compare
ECD_04261 +0.4 1.3 hypothetical protein compare
ECD_02818 +0.4 2.4 Capsule polysaccharide export protein KpsC compare
ECD_04030 +0.4 0.6 phosphatidylserine decarboxylase compare
ECD_01039 +0.4 0.9 curlin subunit, amyloid curli fibers, cryptic compare
ECD_01611 +0.4 1.8 outer membrane lipoprotein compare
ECD_04160 +0.4 1.3 IS1 protein InsA compare
ECD_03456 +0.4 0.9 mannitol operon repressor compare
ECD_00872 +0.4 0.8 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein compare
ECD_01301 +0.4 0.9 lipid hydroperoxide peroxidase compare
ECD_01278 +0.4 1.2 gamma-glutamylputrescine oxidoreductase compare
ECD_02175 +0.4 0.9 inactive PncC family protein compare
ECD_00468 +0.4 1.8 putative NAD(P)-binding acyl-CoA synthetase compare
ECD_02087 +0.4 1.4 UPF0324 family inner membrane protein compare
ECD_04279 +0.4 2.0 putative methyltransferase compare
ECD_02671 +0.4 1.2 putative prepilin peptidase-dependent protein compare
ECD_04252 +0.4 1.0 uncharacterized protein compare
ECD_03969 +0.4 1.5 carbon-phosphorus lyase complex subunit, putative ATP transporter ATP-binding protein compare
ECD_03511 +0.4 2.7 glutamate transporter compare
ECD_01599 +0.4 0.8 SoxR iron-sulfur cluster reduction factor component; putative membrane-associated NADH oxidoreductase of electron transport complex compare
ECD_01289 +0.4 0.9 putative sugar ABC transporter permease compare
ECD_03547 +0.4 1.5 DUF1198 family protein compare
ECD_01959 +0.3 1.2 GDP-D-mannose dehydratase, NAD(P)-binding compare


Specific Phenotypes

None in this experiment

For Escherichia coli BL21 in phage experiments

For phage MOI 10 across organisms