Experiment set9IT096 for Escherichia coli BW25113

Compare to:

LB Anaerobic with Hygromycin B 0.000125 mM

200 most important genes:

  gene name fitness t score description  
b4237 nrdG -3.5 -11.9 anaerobic ribonucleotide reductase activating protein (NCBI) compare
b4238 nrdD -3.5 -18.9 anaerobic ribonucleoside triphosphate reductase (NCBI) compare
b0683 fur -2.9 -1.9 ferric uptake regulator (NCBI) compare
b0902 pflA -2.9 -8.9 pyruvate formate lyase activating enzyme 1 (NCBI) compare
b0053 surA -2.8 -2.7 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b0222 lpcA -2.6 -3.4 phosphoheptose isomerase (NCBI) compare
b0737 tolQ -2.3 -2.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1334 fnr -2.3 -3.0 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b2569 lepA -1.9 -3.8 GTP-binding protein LepA (NCBI) compare
b0903 pflB -1.9 -10.8 pyruvate formate lyase I (NCBI) compare
b1429 tehA -1.9 -2.0 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b4702 mgtL -1.9 -1.7 regulatory leader peptide for mgtA (NCBI) compare
b4025 pgi -1.8 -8.0 glucose-6-phosphate isomerase (NCBI) compare
b1103 ycfF -1.8 -2.0 orf, hypothetical protein (VIMSS) compare
b4535 yniD -1.8 -1.6 predicted protein (RefSeq) compare
b3839 tatC -1.8 -6.1 TatABCE protein translocation system subunit (NCBI) compare
b1765 ydjA -1.7 -1.6 predicted oxidoreductase (NCBI) compare
b0386 proC -1.7 -4.7 pyrroline-5-carboxylate reductase (NCBI) compare
b1293 sapB -1.7 -1.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0677 nagA -1.7 -5.5 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b3390 aroK -1.7 -2.1 shikimate kinase I (NCBI) compare
b0239 frsA -1.6 -8.0 fermentation/respiration switch protein (NCBI) compare
b0741 pal -1.6 -3.6 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b1865 nudB -1.5 -1.5 dATP pyrophosphohydrolase (NCBI) compare
b0781 moaA -1.5 -8.0 molybdenum cofactor biosynthesis protein A (NCBI) compare
b0785 moaE -1.5 -4.4 molybdopterin synthase, large subunit (NCBI) compare
b2859 ygeO -1.4 -1.6 hypothetical protein (RefSeq) compare
b3035 tolC -1.4 -6.7 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b0740 tolB -1.4 -3.3 translocation protein TolB precursor (NCBI) compare
b3857 mobA -1.3 -6.1 molybdopterin-guanine dinucleotide biosynthesis protein A (NCBI) compare
b4509 ylcG -1.3 -2.1 DLP12 prophage; predicted protein (NCBI) compare
b3620 rfaF -1.3 -3.8 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b2576 srmB -1.3 -2.5 ATP-dependent RNA helicase (NCBI) compare
b3229 sspA -1.3 -2.1 stringent starvation protein A (NCBI) compare
b0764 modB -1.3 -4.7 molybdate ABC transporter permease protein (NCBI) compare
b4570 lomR -1.3 -2.0 no description compare
b0009 mog -1.2 -5.9 molybdenum cofactor biosynthesis protein (NCBI) compare
b3916 pfkA -1.2 -1.4 6-phosphofructokinase (NCBI) compare
b0827 moeA -1.2 -4.4 molybdopterin biosynthesis protein (NCBI) compare
b1348 lar -1.2 -1.6 Rac prophage; restriction alleviation protein (NCBI) compare
b1346 ydaQ -1.2 -1.6 orf, hypothetical protein (VIMSS) compare
b0783 moaC -1.2 -4.4 molybdenum cofactor biosynthesis protein C (NCBI) compare
b0688 pgm -1.2 -2.6 phosphoglucomutase (NCBI) compare
b1361 ydaW -1.2 -0.6 orf, hypothetical protein (VIMSS) compare
b2620 smpB -1.2 -1.2 SsrA-binding protein (NCBI) compare
b2363 yfdT -1.2 -1.7 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b3162 deaD -1.2 -2.7 inducible ATP-independent RNA helicase (VIMSS) compare
b3205 yhbJ -1.2 -3.0 hypothetical protein (NCBI) compare
b3621 rfaC -1.2 -3.3 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b1506 yneL -1.1 -1.0 predicted transcriptional regulator (NCBI) compare
b1292 sapC -1.1 -1.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4505 insX -1.1 -1.6 predicted IS protein (RefSeq) compare
b1493 gadB -1.1 -0.8 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b2528 iscA -1.1 -1.1 iron-sulfur cluster assembly protein (NCBI) compare
b3930 menA -1.1 -8.6 1,4-dihydroxy-2-naphthoate octaprenyltransferase (NCBI) compare
b0826 moeB -1.1 -4.9 molybdopterin biosynthesis protein MoeB (NCBI) compare
b1291 sapD -1.1 -1.2 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0739 tolA -1.1 -1.9 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3838 tatB -1.1 -5.7 sec-independent translocase (NCBI) compare
b1176 minC -1.1 -1.8 septum formation inhibitor (NCBI) compare
b0049 apaH -1.1 -2.2 diadenosinetetraphosphatase (NCBI) compare
b2506 yfgI -1.1 -2.1 hypothetical protein (NCBI) compare
b0738 tolR -1.1 -1.5 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4042 dgkA -1.0 -1.7 diacylglycerol kinase (NCBI) compare
b1454 yncG -1.0 -1.9 predicted enzyme (NCBI) compare
b1855 lpxM -1.0 -3.9 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b3706 trmE -1.0 -2.2 tRNA modification GTPase (NCBI) compare
b0082 mraW -1.0 -2.5 S-adenosyl-methyltransferase (NCBI) compare
b3493 pitA -1.0 -4.1 phosphate transporter, low-affinity (NCBI) compare
b1575 dicB -1.0 -1.0 Qin prophage; cell division inhibition protein (NCBI) compare
b1259 yciG -1.0 -1.4 orf, hypothetical protein (VIMSS) compare
b4503 yafF -1.0 -0.8 no description compare
b2498 upp -1.0 -2.0 uracil phosphoribosyltransferase (VIMSS) compare
b3792 wzxE -1.0 -4.2 O-antigen translocase (NCBI) compare
b3052 rfaE -1.0 -3.4 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3082 ygjM -1.0 -1.3 predicted DNA-binding transcriptional regulator (NCBI) compare
b2479 gcvR -1.0 -3.4 transcriptional regulation of gcv operon (VIMSS) compare
b2085 b2085 -1.0 -2.3 orf, hypothetical protein (VIMSS) compare
b1021 ycdP -0.9 -3.3 predicted inner membrane protein (NCBI) compare
b2512 yfgL -0.9 -3.8 protein assembly complex, lipoprotein component (NCBI) compare
b0998 torD -0.9 -1.1 chaperone protein TorD (NCBI) compare
b3619 rfaD -0.9 -2.3 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b1355 b1355 -0.9 -2.7 orf, hypothetical protein (VIMSS) compare
b3741 gidA -0.9 -2.0 glucose-inhibited division protein A (NCBI) compare
b3781 trxA -0.9 -2.6 thioredoxin 1 (VIMSS) compare
b2376 ypdI -0.9 -1.7 predicted lipoprotein involved in colanic acid biosynthesis (NCBI) compare
b4184 yjfL -0.9 -2.2 conserved inner membrane protein (NCBI) compare
b0439 lon -0.9 -2.7 DNA-binding ATP-dependent protease La (NCBI) compare
b3726 pstA -0.9 -2.6 phosphate transporter subunit (NCBI) compare
b0232 yafN -0.9 -0.5 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b3649 rpoZ -0.9 -1.9 DNA-directed RNA polymerase subunit omega (NCBI) compare
b0763 modA -0.9 -3.5 molybdate transporter subunit (NCBI) compare
b1642 slyA -0.9 -1.5 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b3631 rfaG -0.9 -6.1 glucosyltransferase I (NCBI) compare
b3443 yrhA -0.8 -1.0 orf, hypothetical protein (VIMSS) compare
b3163 nlpI -0.8 -3.0 hypothetical protein (NCBI) compare
b1123 potD -0.8 -3.3 spermidine/putrescine ABC transporter periplasmic substrate-binding protein (NCBI) compare
b2808 gcvA -0.8 -2.0 DNA-binding transcriptional dual regulator (NCBI) compare
b3183 obgE -0.8 -0.7 GTPase involved in cell partioning and DNA repair (NCBI) compare
b1863 ruvC -0.8 -0.7 Holliday junction resolvase (NCBI) compare
b0970 yccA -0.8 -2.6 inner membrane protein (NCBI) compare
b2937 speB -0.8 -4.0 agmatinase (NCBI) compare
b1236 galU -0.8 -2.1 glucose-1-phosphate uridylyltransferase (NCBI) compare
b1677 lpp -0.8 -1.4 murein lipoprotein (NCBI) compare
b1241 adhE -0.8 -5.2 fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase (NCBI) compare
b0765 modC -0.8 -3.2 molybdate transporter subunit (NCBI) compare
b4175 hflC -0.8 -4.9 modulator for HflB protease specific for phage lambda cII repressor (NCBI) compare
b3728 pstS -0.8 -1.3 phosphate transporter subunit (NCBI) compare
b3836 b3836 -0.8 -3.1 orf, hypothetical protein (VIMSS) compare
b1556 b1556 -0.8 -1.3 orf, hypothetical protein (VIMSS) compare
b4640 yoeG -0.8 -1.0 no description compare
b2617 smpA -0.8 -1.8 small membrane protein A (VIMSS) compare
b3094 exuR -0.8 -2.5 negative regulator of exu regulon, exuT, uxaAC, and uxuB (VIMSS) compare
b4589 ylcI -0.8 -1.3 hypothetical protein (RefSeq) compare
b0533 sfmH -0.8 -3.1 predicted fimbrial-like adhesin protein (RefSeq) compare
b0437 clpP -0.8 -3.0 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b2830 nudH -0.8 -0.9 dinucleoside polyphosphate hydrolase (NCBI) compare
b4592 yccB -0.8 -1.5 hypothetical protein (RefSeq) compare
b0145 dksA -0.7 -1.7 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b2104 thiM -0.7 -2.2 hydroxyethylthiazole kinase (NCBI) compare
b4243 yjgF -0.7 -3.2 orf, hypothetical protein (VIMSS) compare
b0237 pepD -0.7 -4.0 aminoacyl-histidine dipeptidase (peptidase D) (NCBI) compare
b3157 yhbT -0.7 -1.9 predicted lipid carrier protein (NCBI) compare
b2329 aroC -0.7 -2.7 chorismate synthase (NCBI) compare
b0505 allA -0.7 -2.1 ureidoglycolate hydrolase (NCBI) compare
b3613 yibP -0.7 -1.0 putative membrane protein (VIMSS) compare
b4174 hflK -0.7 -4.5 modulator for HflB protease specific for phage lambda cII repressor (NCBI) compare
b1861 ruvA -0.7 -0.4 Holliday junction DNA helicase motor protein (NCBI) compare
b0051 ksgA -0.7 -2.0 dimethyladenosine transferase (NCBI) compare
b1961 dcm -0.7 -1.2 DNA cytosine methylase (NCBI) compare
b0957 ompA -0.7 -2.1 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b0406 tgt -0.7 -3.4 queuine tRNA-ribosyltransferase (NCBI) compare
b3164 pnp -0.7 -1.4 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b1028 ymdE -0.7 -2.1 orf, hypothetical protein (VIMSS) compare
b3609 secB -0.7 -2.2 export protein SecB (NCBI) compare
b1582 ynfA -0.7 -1.6 hypothetical protein (NCBI) compare
b4585 sroB -0.7 -0.8 Novel sRNA, function unknown (RefSeq) compare
b2237 inaA -0.7 -1.9 hypothetical protein (NCBI) compare
b2258 b2258 -0.7 -1.0 putative transport/receptor protein (VIMSS) compare
b2501 ppk -0.7 -4.0 polyphosphate kinase (NCBI) compare
b4418 sraB -0.7 -1.4 unknown RNA (NCBI) compare
b3237 argR -0.7 -2.2 arginine repressor (NCBI) compare
b1025 ycdT -0.7 -0.7 predicted diguanylate cyclase (NCBI) compare
b0728 sucC -0.7 -2.8 succinyl-CoA synthetase subunit beta (NCBI) compare
b3204 ptsN -0.7 -2.6 sugar-specific enzyme IIA component of PTS (NCBI) compare
b2369 evgA -0.7 -1.3 DNA-binding response regulator in two-component regulatory system with EvgS (NCBI) compare
b0729 sucD -0.7 -1.6 succinyl-CoA synthetase subunit alpha (NCBI) compare
b4179 vacB -0.7 -2.7 putative enzyme (VIMSS) compare
b4532 yncN -0.7 -2.0 orf, hypothetical protein (VIMSS) compare
b1141 ymfG -0.7 -1.4 e14 prophage; predicted excisionase (NCBI) compare
b1290 sapF -0.7 -1.0 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1951 rcsA -0.7 -0.6 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b0784 moaD -0.7 -1.0 molybdopterin synthase, small subunit (NCBI) compare
b2202 napC -0.7 -2.1 nitrate reductase, cytochrome c-type, periplasmic (NCBI) compare
b1258 yciF -0.6 -0.4 hypothetical protein (NCBI) compare
b1279 yciS -0.6 -0.8 conserved inner membrane protein (NCBI) compare
b3129 sohA -0.6 -2.1 predicted regulator (NCBI) compare
b1125 potB -0.6 -2.0 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b3698 yidB -0.6 -2.0 orf, hypothetical protein (VIMSS) compare
b3858 yihD -0.6 -1.5 hypothetical protein (NCBI) compare
b1877 yecT -0.6 -0.8 orf, hypothetical protein (VIMSS) compare
b2274 yfbO -0.6 -1.9 predicted protein (RefSeq) compare
b2187 yejL -0.6 -1.7 hypothetical protein (NCBI) compare
b2288 nuoA -0.6 -1.8 NADH dehydrogenase I chain A (VIMSS) compare
b3349 slyD -0.6 -3.0 FKBP-type peptidyl prolyl cis-trans isomerase (rotamase) (NCBI) compare
b3500 gor -0.6 -0.8 glutathione reductase (NCBI) compare
b1614 ydgA -0.6 -1.8 hypothetical protein (NCBI) compare
b1518 lsrG -0.6 -1.1 autoinducer-2 (AI-2) modifying protein LsrG (NCBI) compare
b2175 spr -0.6 -1.9 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b1536 ydeI -0.6 -0.4 hypothetical protein (NCBI) compare
b3341 rpsG -0.6 -0.8 30S ribosomal protein S7 (NCBI) compare
b1150 ymfR -0.6 -0.7 e14 prophage; predicted protein (NCBI) compare
b0462 acrB -0.6 -5.1 multidrug efflux system protein (NCBI) compare
b3630 rfaP -0.6 -3.5 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b4313 fimE -0.6 -3.1 tyrosine recombinase/inversion of on/off regulator of fimA (NCBI) compare
b0460 hha -0.6 -1.9 modulator of gene expression, with H-NS (NCBI) compare
b3778 rep -0.6 -2.9 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b1450 b1450 -0.6 -2.1 orf, hypothetical protein (VIMSS) compare
b0890 ftsK -0.6 -1.2 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b1579 intQ -0.6 -1.0 Qin prophage; predicted defective integrase (RefSeq) compare
b1498 b1498 -0.6 -2.2 putative sulfatase (VIMSS) compare
b1183 umuD -0.6 -1.2 DNA polymerase V, subunit D (NCBI) compare
b0965 b0965 -0.6 -1.1 orf, hypothetical protein (VIMSS) compare
b3761 trpT -0.6 -1.0 tRNA-Trp (NCBI) compare
b0706 ybfD -0.6 -0.6 hypothetical protein (NCBI) compare
b1860 ruvB -0.6 -0.3 Holliday junction DNA helicase B (NCBI) compare
b0225 yafQ -0.6 -1.2 predicted toxin of the YafQ-DinJ toxin-antitoxin system (NCBI) compare
b1438 ydcQ -0.6 -1.3 predicted DNA-binding transcriptional regulator (RefSeq) compare
b1255 yciC -0.6 -1.8 hypothetical protein (NCBI) compare
b1992 cobS -0.6 -1.1 cobalamin synthase (NCBI) compare
b3465 yhhF -0.6 -2.3 predicted methyltransferase (NCBI) compare
b1304 pspA -0.6 -1.5 regulatory protein for phage-shock-protein operon (NCBI) compare
b3264 envR -0.6 -1.2 DNA-binding transcriptional regulator (NCBI) compare
b4255 yjgD -0.6 -2.2 hypothetical protein (NCBI) compare
b4035 malK -0.6 -3.2 fused maltose transport subunit, ATP-binding component of ABC superfamily/regulatory protein (NCBI) compare
b3803 hemX -0.6 -3.7 predicted uroporphyrinogen III methylase (NCBI) compare
b1634 tppB -0.6 -2.1 putative tripeptide transporter permease (NCBI) compare
b2343 b2343 -0.6 -1.0 orf, hypothetical protein (VIMSS) compare
b1690 ydiM -0.6 -0.4 predicted transporter (NCBI) compare
b0381 ddlA -0.6 -2.7 D-alanylalanine synthetase (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in stress experiments

For stress Hygromycin B across organisms