Experiment set9IT044 for Escherichia coli BW25113

Compare to:

LB Anaerobic with Amoxicillin 0.00000390625 mM

200 most important genes:

  gene name fitness t score description  
b1105 ycfM -5.9 -4.0 predicted outer membrane lipoprotein (NCBI) compare
b0149 mrcB -4.3 -7.1 penicillin-binding protein 1b (NCBI) compare
b1192 ldcA -4.2 -6.3 L,D-carboxypeptidase A (NCBI) compare
b1334 fnr -3.7 -3.5 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b4025 pgi -3.6 -7.9 glucose-6-phosphate isomerase (NCBI) compare
b0741 pal -3.5 -2.4 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b4392 slt -3.4 -16.2 soluble lytic murein transglycosylase (VIMSS) compare
b4238 nrdD -3.2 -19.0 anaerobic ribonucleoside triphosphate reductase (NCBI) compare
b0737 tolQ -3.1 -2.1 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4237 nrdG -3.1 -11.8 anaerobic ribonucleotide reductase activating protein (NCBI) compare
b1103 ycfF -3.0 -2.0 orf, hypothetical protein (VIMSS) compare
b4150 ampC -2.9 -11.7 beta-lactamase/D-alanine carboxypeptidase (NCBI) compare
b0433 ampG -2.8 -17.1 muropeptide transporter (NCBI) compare
b3792 wzxE -2.7 -4.8 O-antigen translocase (NCBI) compare
b0740 tolB -2.6 -2.5 translocation protein TolB precursor (NCBI) compare
b1429 tehA -2.6 -2.3 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b0381 ddlA -2.6 -8.6 D-alanylalanine synthetase (NCBI) compare
b0902 pflA -2.4 -8.0 pyruvate formate lyase activating enzyme 1 (NCBI) compare
b3390 aroK -2.3 -2.2 shikimate kinase I (NCBI) compare
b0739 tolA -2.2 -1.5 cell envelope integrity inner membrane protein TolA (NCBI) compare
b0957 ompA -2.2 -4.6 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b4535 yniD -2.2 -1.5 predicted protein (RefSeq) compare
b2528 iscA -2.2 -2.4 iron-sulfur cluster assembly protein (NCBI) compare
b2830 nudH -2.1 -1.4 dinucleoside polyphosphate hydrolase (NCBI) compare
b0053 surA -2.1 -4.8 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b0222 lpcA -2.1 -3.7 phosphoheptose isomerase (NCBI) compare
b3609 secB -2.1 -5.2 export protein SecB (NCBI) compare
b0903 pflB -2.0 -11.4 pyruvate formate lyase I (NCBI) compare
b2576 srmB -2.0 -3.7 ATP-dependent RNA helicase (NCBI) compare
b2175 spr -2.0 -4.2 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b1765 ydjA -1.9 -1.8 predicted oxidoreductase (NCBI) compare
b1104 ycfL -1.8 -2.1 hypothetical protein (NCBI) compare
b1150 ymfR -1.8 -1.7 e14 prophage; predicted protein (NCBI) compare
b4053 alr -1.8 -8.2 alanine racemase (NCBI) compare
b1882 cheY -1.7 -0.9 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b0738 tolR -1.7 -1.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3839 tatC -1.7 -6.3 TatABCE protein translocation system subunit (NCBI) compare
b3229 sspA -1.7 -2.6 stringent starvation protein A (NCBI) compare
b1850 eda -1.6 -2.6 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b1506 yneL -1.6 -1.3 predicted transcriptional regulator (NCBI) compare
b3930 menA -1.6 -11.7 1,4-dihydroxy-2-naphthoate octaprenyltransferase (NCBI) compare
b1863 ruvC -1.6 -1.4 Holliday junction resolvase (NCBI) compare
b0866 ybjQ -1.5 -1.8 hypothetical protein (NCBI) compare
b0239 frsA -1.5 -6.6 fermentation/respiration switch protein (NCBI) compare
b1290 sapF -1.4 -2.0 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0434 yajG -1.4 -5.2 putative polymerase/proteinase (VIMSS) compare
b3443 yrhA -1.4 -1.3 orf, hypothetical protein (VIMSS) compare
b0783 moaC -1.4 -5.4 molybdenum cofactor biosynthesis protein C (NCBI) compare
b1176 minC -1.4 -2.7 septum formation inhibitor (NCBI) compare
b0764 modB -1.4 -3.9 molybdate ABC transporter permease protein (NCBI) compare
b0386 proC -1.4 -4.3 pyrroline-5-carboxylate reductase (NCBI) compare
b0920 ycbC -1.3 -4.1 conserved inner membrane protein (NCBI) compare
b3836 b3836 -1.3 -4.9 orf, hypothetical protein (VIMSS) compare
b1161 ycgX -1.3 -0.9 hypothetical protein (NCBI) compare
b3341 rpsG -1.3 -1.5 30S ribosomal protein S7 (NCBI) compare
b4413 sokC -1.3 -1.9 regulatory antisense RNA (NCBI) compare
b0677 nagA -1.3 -4.8 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b1361 ydaW -1.3 -0.6 orf, hypothetical protein (VIMSS) compare
b4402 yjjY -1.3 -1.1 hypothetical protein (NCBI) compare
b2506 yfgI -1.2 -2.4 hypothetical protein (NCBI) compare
b3164 pnp -1.2 -2.2 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b1961 dcm -1.2 -1.8 DNA cytosine methylase (NCBI) compare
b0145 dksA -1.2 -2.5 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b4431 rprA -1.2 -1.9 Positive regulatory sRNA for RpoS translation; non-essential gene (RefSeq) compare
b2215 ompC -1.2 -6.5 outer membrane porin protein C (NCBI) compare
b3838 tatB -1.2 -6.0 sec-independent translocase (NCBI) compare
b4545 ypdJ -1.1 -1.8 no description compare
b1293 sapB -1.1 -1.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3916 pfkA -1.1 -1.5 6-phosphofructokinase (NCBI) compare
b4701 sokX -1.1 -0.7 sok-related sRNA, function unknown (RefSeq) compare
b3094 exuR -1.1 -4.4 negative regulator of exu regulon, exuT, uxaAC, and uxuB (VIMSS) compare
b0785 moaE -1.1 -4.3 molybdopterin synthase, large subunit (NCBI) compare
b0990 cspG -1.1 -0.7 DNA-binding transcriptional regulator (NCBI) compare
b0728 sucC -1.1 -4.8 succinyl-CoA synthetase subunit beta (NCBI) compare
b1848 yebG -1.1 -1.5 conserved protein regulated by LexA (NCBI) compare
b0826 moeB -1.1 -4.7 molybdopterin biosynthesis protein MoeB (NCBI) compare
b0782 moaB -1.1 -1.4 molybdopterin biosynthesis protein B (NCBI) compare
b3613 yibP -1.0 -1.2 putative membrane protein (VIMSS) compare
b0237 pepD -1.0 -5.2 aminoacyl-histidine dipeptidase (peptidase D) (NCBI) compare
b0049 apaH -1.0 -2.2 diadenosinetetraphosphatase (NCBI) compare
b1573 ydfC -1.0 -0.8 Qin prophage; predicted protein (RefSeq) compare
b2620 smpB -1.0 -1.0 SsrA-binding protein (NCBI) compare
b3649 rpoZ -1.0 -2.1 DNA-directed RNA polymerase subunit omega (NCBI) compare
b1346 ydaQ -1.0 -1.5 orf, hypothetical protein (VIMSS) compare
b0765 modC -1.0 -3.7 molybdate transporter subunit (NCBI) compare
b3183 obgE -1.0 -0.8 GTPase involved in cell partioning and DNA repair (NCBI) compare
b3349 slyD -1.0 -4.7 FKBP-type peptidyl prolyl cis-trans isomerase (rotamase) (NCBI) compare
b3199 yrbK -1.0 -2.2 hypothetical protein (NCBI) compare
b2318 truA -1.0 -2.1 tRNA pseudouridine synthase A (NCBI) compare
b0949 uup -1.0 -4.9 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b3863 polA -1.0 -0.6 DNA polymerase I (NCBI) compare
b0009 mog -0.9 -5.1 molybdenum cofactor biosynthesis protein (NCBI) compare
b1677 lpp -0.9 -1.8 murein lipoprotein (NCBI) compare
b1684 sufA -0.9 -1.4 iron-sulfur cluster assembly scaffold protein (NCBI) compare
b0729 sucD -0.9 -2.5 succinyl-CoA synthetase subunit alpha (NCBI) compare
b1936 intG -0.9 -0.8 predicted defective phage integrase (pseudogene) (RefSeq) compare
b0781 moaA -0.9 -4.9 molybdenum cofactor biosynthesis protein A (NCBI) compare
b1291 sapD -0.9 -1.0 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3052 rfaE -0.9 -3.3 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3629 rfaS -0.9 -1.5 lipopolysaccharide core biosynthesis protein (NCBI) compare
b0827 moeA -0.9 -3.5 molybdopterin biosynthesis protein (NCBI) compare
b1292 sapC -0.9 -1.6 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3871 bipA -0.9 -5.7 GTP-binding protein (NCBI) compare
b0142 folK -0.9 -0.4 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b0232 yafN -0.9 -0.5 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b3619 rfaD -0.9 -2.3 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b1730 ydjO -0.9 -0.5 predicted protein (RefSeq) compare
b2512 yfgL -0.9 -3.5 protein assembly complex, lipoprotein component (NCBI) compare
b1634 tppB -0.9 -3.2 putative tripeptide transporter permease (NCBI) compare
b3621 rfaC -0.9 -2.9 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b3791 rffA -0.9 -4.5 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b1579 intQ -0.9 -1.0 Qin prophage; predicted defective integrase (RefSeq) compare
b2569 lepA -0.8 -2.5 GTP-binding protein LepA (NCBI) compare
b0110 ampD -0.8 -4.2 N-acetyl-anhydromuranmyl-L-alanine amidase (NCBI) compare
b1217 chaB -0.8 -1.1 cation transport regulator (NCBI) compare
b0535 fimZ -0.8 -1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b2291 yfbR -0.8 -2.4 hypothetical protein (NCBI) compare
b3500 gor -0.8 -1.0 glutathione reductase (NCBI) compare
b1048 mdoG -0.8 -3.3 glucan biosynthesis protein, periplasmic (NCBI) compare
b0763 modA -0.8 -3.4 molybdate transporter subunit (NCBI) compare
b3857 mobA -0.8 -3.0 molybdopterin-guanine dinucleotide biosynthesis protein A (NCBI) compare
b1951 rcsA -0.8 -0.5 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b3388 damX -0.8 -6.3 hypothetical protein (NCBI) compare
b1531 marA -0.8 -1.9 multiple antibiotic resistance; transcriptional activator of defense systems (VIMSS) compare
b1164 ycgZ -0.8 -0.5 hypothetical protein (NCBI) compare
b0088 murD -0.8 -1.5 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b2362 yfdS -0.8 -2.8 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b1785 yeaI -0.8 -1.0 predicted diguanylate cyclase (NCBI) compare
b0706 ybfD -0.8 -0.7 hypothetical protein (NCBI) compare
b3761 trpT -0.8 -1.4 tRNA-Trp (NCBI) compare
b1540 ydfH -0.8 -1.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b3741 gidA -0.8 -1.9 glucose-inhibited division protein A (NCBI) compare
b1259 yciG -0.8 -1.2 orf, hypothetical protein (VIMSS) compare
b4513 kdpF -0.8 -2.1 potassium ion accessory transporter subunit (NCBI) compare
b4201 priB -0.8 -1.8 primosomal replication protein N (NCBI) compare
b2479 gcvR -0.8 -2.9 transcriptional regulation of gcv operon (VIMSS) compare
b1109 ndh -0.8 -2.3 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b2101 yegW -0.8 -2.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b1598 ydgD -0.8 -3.2 predicted peptidase (NCBI) compare
b2329 aroC -0.7 -2.6 chorismate synthase (NCBI) compare
b1689 b1689 -0.7 -1.7 orf, hypothetical protein (VIMSS) compare
b1025 ycdT -0.7 -0.8 predicted diguanylate cyclase (NCBI) compare
b2165 yeiN -0.7 -2.7 hypothetical protein (NCBI) compare
b2646 ypjF -0.7 -1.8 CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system (NCBI) compare
b0548 ninE -0.7 -1.8 DLP12 prophage; conserved protein (NCBI) compare
b4179 vacB -0.7 -2.8 putative enzyme (VIMSS) compare
b3628 rfaB -0.7 -4.0 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b0908 aroA -0.7 -4.0 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b0439 lon -0.7 -2.3 DNA-binding ATP-dependent protease La (NCBI) compare
b1107 nagZ -0.7 -2.2 beta-hexosaminidase (NCBI) compare
b1258 yciF -0.7 -0.4 hypothetical protein (NCBI) compare
b3545 proK -0.7 -1.2 tRNA-Pro (NCBI) compare
b2274 yfbO -0.7 -2.1 predicted protein (RefSeq) compare
b2809 b2809 -0.7 -1.5 orf, hypothetical protein (VIMSS) compare
b1536 ydeI -0.7 -0.4 hypothetical protein (NCBI) compare
b1358 ydaT -0.7 -0.8 Rac prophage; predicted protein (NCBI) compare
b3387 dam -0.7 -4.5 DNA adenine methylase (NCBI) compare
b3784 rfe -0.7 -4.9 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b1877 yecT -0.7 -0.9 orf, hypothetical protein (VIMSS) compare
b4640 yoeG -0.7 -1.0 no description compare
b2369 evgA -0.7 -1.3 DNA-binding response regulator in two-component regulatory system with EvgS (NCBI) compare
b1600 mdtJ -0.7 -0.9 multidrug efflux system transporter (NCBI) compare
b0895 dmsB -0.7 -2.9 dimethyl sulfoxide reductase, anaerobic, subunit B (NCBI) compare
b3787 rffD -0.7 -4.5 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b0970 yccA -0.7 -2.1 inner membrane protein (NCBI) compare
b2993 hybD -0.7 -2.4 predicted maturation element for hydrogenase 2 (NCBI) compare
b4171 miaA -0.7 -1.4 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b0623 cspE -0.6 -1.2 cold shock protein E (NCBI) compare
b1446 ydcY -0.6 -1.2 hypothetical protein (NCBI) compare
b2350 yfdG -0.6 -3.2 CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) (NCBI) compare
b1835 yebU -0.6 -1.7 putative nucleolar proteins (VIMSS) compare
b1448 yncA -0.6 -1.2 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b2282 nuoH -0.6 -1.7 NADH dehydrogenase subunit H (NCBI) compare
b3169 nusA -0.6 -1.2 transcription elongation factor NusA (NCBI) compare
b3150 yraP -0.6 -3.0 hypothetical protein (NCBI) compare
b1968 yedV -0.6 -1.1 predicted sensory kinase in two-component regulatory system with YedW (NCBI) compare
b1108 ycfP -0.6 -1.1 orf, hypothetical protein (VIMSS) compare
b1505 ydeT -0.6 -0.4 hypothetical protein (RefSeq) compare
b2104 thiM -0.6 -1.9 hydroxyethylthiazole kinase (NCBI) compare
b1823 cspC -0.6 -1.0 stress protein, member of the CspA-family (NCBI) compare
b1021 ycdP -0.6 -2.3 predicted inner membrane protein (NCBI) compare
b3237 argR -0.6 -2.0 arginine repressor (NCBI) compare
b3205 yhbJ -0.6 -1.8 hypothetical protein (NCBI) compare
b0730 mngR -0.6 -0.6 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b1503 ydeR -0.6 -1.5 predicted fimbrial-like adhesin protein (NCBI) compare
b4169 amiB -0.6 -4.3 N-acetylmuramoyl-l-alanine amidase II (NCBI) compare
b4435 isrC -0.6 -1.3 unknown RNA (NCBI) compare
b1040 csgD -0.6 -0.5 DNA-binding transcriptional activator in two-component regulatory system (NCBI) compare
b1175 minD -0.6 -1.9 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b1836 yebV -0.6 -1.6 orf, hypothetical protein (VIMSS) compare
b4593 ymgI -0.6 -0.3 hypothetical protein (RefSeq) compare
b4520 ymgF -0.6 -0.6 hypothetical protein (NCBI) compare
b1179 ycgL -0.6 -1.2 conserved protein (NCBI) compare
b1363 trkG -0.6 -0.3 Rac prophage; potassium transporter subunit (NCBI) compare
b4481 rffT -0.6 -2.7 4-alpha-L-fucosyltransferase (NCBI) compare
b3786 rffE -0.6 -4.0 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b2279 nuoK -0.6 -1.0 NADH dehydrogenase subunit K (NCBI) compare
b2553 glnB -0.6 -2.0 regulatory protein P-II for glutamine synthetase (NCBI) compare
b1298 ycjL -0.6 -1.9 probable amidotransferase subunit (VIMSS) compare
b1658 purR -0.6 -2.3 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare


Specific Phenotypes

For 5 genes in this experiment

For stress Amoxicillin in Escherichia coli BW25113

For stress Amoxicillin across organisms