Experiment set9IT036 for Escherichia coli BW25113

Compare to:

LB Anaerobic with Spectinomycin dihydrochloride pentahydrate 0.00003125 mM

200 most important genes:

  gene name fitness t score description  
b4238 nrdD -3.4 -19.1 anaerobic ribonucleoside triphosphate reductase (NCBI) compare
b4237 nrdG -3.2 -12.4 anaerobic ribonucleotide reductase activating protein (NCBI) compare
b1334 fnr -2.9 -2.8 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b0053 surA -2.8 -3.8 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b2620 smpB -2.3 -1.5 SsrA-binding protein (NCBI) compare
b0737 tolQ -2.2 -2.9 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4535 yniD -2.2 -1.5 predicted protein (RefSeq) compare
b3341 rpsG -2.2 -2.0 30S ribosomal protein S7 (NCBI) compare
b0677 nagA -2.1 -6.2 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b0902 pflA -2.1 -8.1 pyruvate formate lyase activating enzyme 1 (NCBI) compare
b0222 lpcA -2.1 -3.7 phosphoheptose isomerase (NCBI) compare
b0683 fur -2.0 -1.8 ferric uptake regulator (NCBI) compare
b4025 pgi -2.0 -8.5 glucose-6-phosphate isomerase (NCBI) compare
b0903 pflB -1.9 -11.1 pyruvate formate lyase I (NCBI) compare
b1346 ydaQ -1.9 -2.1 orf, hypothetical protein (VIMSS) compare
b3839 tatC -1.8 -6.0 TatABCE protein translocation system subunit (NCBI) compare
b0226 dinJ -1.8 -5.3 predicted antitoxin of YafQ-DinJ toxin-antitoxin system (NCBI) compare
b3229 sspA -1.8 -2.8 stringent starvation protein A (NCBI) compare
b1236 galU -1.8 -3.4 glucose-1-phosphate uridylyltransferase (NCBI) compare
b2576 srmB -1.8 -3.0 ATP-dependent RNA helicase (NCBI) compare
b4503 yafF -1.8 -1.2 no description compare
b3836 b3836 -1.7 -5.5 orf, hypothetical protein (VIMSS) compare
b0049 apaH -1.6 -2.8 diadenosinetetraphosphatase (NCBI) compare
b0730 mngR -1.6 -1.1 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b2642 yfjW -1.6 -1.0 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b1677 lpp -1.6 -2.8 murein lipoprotein (NCBI) compare
b3052 rfaE -1.5 -4.8 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b0785 moaE -1.5 -4.8 molybdopterin synthase, large subunit (NCBI) compare
b3930 menA -1.5 -11.0 1,4-dihydroxy-2-naphthoate octaprenyltransferase (NCBI) compare
b0740 tolB -1.4 -3.6 translocation protein TolB precursor (NCBI) compare
b2512 yfgL -1.4 -5.3 protein assembly complex, lipoprotein component (NCBI) compare
b0239 frsA -1.4 -7.8 fermentation/respiration switch protein (NCBI) compare
b1259 yciG -1.4 -1.8 orf, hypothetical protein (VIMSS) compare
b2376 ypdI -1.4 -2.2 predicted lipoprotein involved in colanic acid biosynthesis (NCBI) compare
b0784 moaD -1.4 -2.9 molybdopterin synthase, small subunit (NCBI) compare
b0763 modA -1.4 -5.1 molybdate transporter subunit (NCBI) compare
b2579 yfiD -1.4 -2.1 pyruvate formate lyase subunit (NCBI) compare
b4480 hdfR -1.4 -4.9 transcriptional regulator HdfR (NCBI) compare
b0688 pgm -1.4 -3.0 phosphoglucomutase (NCBI) compare
b0386 proC -1.3 -4.3 pyrroline-5-carboxylate reductase (NCBI) compare
b0764 modB -1.3 -4.3 molybdate ABC transporter permease protein (NCBI) compare
b3163 nlpI -1.3 -4.2 hypothetical protein (NCBI) compare
b0741 pal -1.3 -3.3 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b3857 mobA -1.3 -6.0 molybdopterin-guanine dinucleotide biosynthesis protein A (NCBI) compare
b1291 sapD -1.3 -1.4 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3204 ptsN -1.3 -4.2 sugar-specific enzyme IIA component of PTS (NCBI) compare
b1550 b1550 -1.3 -1.2 orf, hypothetical protein (VIMSS) compare
b4702 mgtL -1.3 -1.7 regulatory leader peptide for mgtA (NCBI) compare
b1591 b1591 -1.3 -1.6 putative oxidoreductase component (VIMSS) compare
b0739 tolA -1.2 -2.1 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1361 ydaW -1.2 -0.6 orf, hypothetical protein (VIMSS) compare
b1850 eda -1.2 -2.1 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b4407 thiS -1.2 -1.9 sulfur carrier protein ThiS (NCBI) compare
b0437 clpP -1.2 -4.5 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b3035 tolC -1.2 -6.0 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3162 deaD -1.2 -2.8 inducible ATP-independent RNA helicase (VIMSS) compare
b3838 tatB -1.2 -6.2 sec-independent translocase (NCBI) compare
b2859 ygeO -1.2 -1.6 hypothetical protein (RefSeq) compare
b3443 yrhA -1.2 -1.1 orf, hypothetical protein (VIMSS) compare
b1493 gadB -1.2 -0.8 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b0888 trxB -1.2 -2.5 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b0082 mraW -1.2 -2.7 S-adenosyl-methyltransferase (NCBI) compare
b1518 lsrG -1.2 -1.8 autoinducer-2 (AI-2) modifying protein LsrG (NCBI) compare
b1335 ogt -1.2 -2.4 O-6-alkylguanine-DNA:cysteine-protein methyltransferase (NCBI) compare
b4701 sokX -1.1 -0.7 sok-related sRNA, function unknown (RefSeq) compare
b3129 sohA -1.1 -3.4 predicted regulator (NCBI) compare
b0009 mog -1.1 -5.9 molybdenum cofactor biosynthesis protein (NCBI) compare
b0783 moaC -1.1 -4.6 molybdenum cofactor biosynthesis protein C (NCBI) compare
b0765 modC -1.1 -4.5 molybdate transporter subunit (NCBI) compare
b0990 cspG -1.1 -0.7 DNA-binding transcriptional regulator (NCBI) compare
b4406 yaeP -1.1 -2.0 hypothetical protein (NCBI) compare
b2498 upp -1.1 -2.3 uracil phosphoribosyltransferase (VIMSS) compare
b1187 fadR -1.0 -4.4 fatty acid metabolism regulator (NCBI) compare
b4509 ylcG -1.0 -2.1 DLP12 prophage; predicted protein (NCBI) compare
b0548 ninE -1.0 -2.4 DLP12 prophage; conserved protein (NCBI) compare
b3390 aroK -1.0 -1.4 shikimate kinase I (NCBI) compare
b0949 uup -1.0 -5.1 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b0729 sucD -1.0 -2.4 succinyl-CoA synthetase subunit alpha (NCBI) compare
b0145 dksA -1.0 -2.2 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b1125 potB -1.0 -3.3 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b0728 sucC -1.0 -4.2 succinyl-CoA synthetase subunit beta (NCBI) compare
b4201 priB -1.0 -2.2 primosomal replication protein N (NCBI) compare
b0827 moeA -1.0 -3.7 molybdopterin biosynthesis protein (NCBI) compare
b2553 glnB -1.0 -3.1 regulatory protein P-II for glutamine synthetase (NCBI) compare
b1977 asnT -1.0 -1.9 tRNA-Asn (NCBI) compare
b1429 tehA -1.0 -1.3 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b1830 prc -1.0 -3.2 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b4179 vacB -1.0 -3.4 putative enzyme (VIMSS) compare
b1049 mdoH -1.0 -5.4 glucosyltransferase MdoH (NCBI) compare
b2569 lepA -0.9 -2.6 GTP-binding protein LepA (NCBI) compare
b4171 miaA -0.9 -1.9 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b2998 yghW -0.9 -2.5 hypothetical protein (NCBI) compare
b3619 rfaD -0.9 -2.4 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b0957 ompA -0.9 -2.7 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b4042 dgkA -0.9 -1.6 diacylglycerol kinase (NCBI) compare
b0232 yafN -0.9 -0.5 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b4184 yjfL -0.9 -2.3 conserved inner membrane protein (NCBI) compare
b3181 greA -0.9 -3.1 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b3871 bipA -0.9 -5.8 GTP-binding protein (NCBI) compare
b3237 argR -0.9 -2.5 arginine repressor (NCBI) compare
b0826 moeB -0.9 -3.9 molybdopterin biosynthesis protein MoeB (NCBI) compare
b1192 ldcA -0.9 -3.4 L,D-carboxypeptidase A (NCBI) compare
b2061 wzb -0.9 -1.7 protein-tyrosine phosphatase (NCBI) compare
b1358 ydaT -0.9 -1.0 Rac prophage; predicted protein (NCBI) compare
b1730 ydjO -0.9 -0.5 predicted protein (RefSeq) compare
b1593 b1593 -0.9 -1.9 orf, hypothetical protein (VIMSS) compare
b3621 rfaC -0.9 -2.8 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b1348 lar -0.9 -1.2 Rac prophage; restriction alleviation protein (NCBI) compare
b4685 yrbN -0.8 -1.6 expressed protein (RefSeq) compare
b3021 ygiT -0.8 -1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b3609 secB -0.8 -2.2 export protein SecB (NCBI) compare
b1482 osmC -0.8 -1.2 osmotically inducible, stress-inducible membrane protein (NCBI) compare
b0535 fimZ -0.8 -1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b1530 marR -0.8 -2.1 multiple antibiotic resistance protein; repressor of mar operon (VIMSS) compare
b1724 ydiZ -0.8 -1.4 hypothetical protein (NCBI) compare
b0088 murD -0.8 -1.5 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b1382 ynbE -0.8 -1.3 predicted lipoprotein (NCBI) compare
b4418 sraB -0.8 -1.6 unknown RNA (NCBI) compare
b3741 gidA -0.8 -2.1 glucose-inhibited division protein A (NCBI) compare
b0802 ybiJ -0.8 -1.8 hypothetical protein (NCBI) compare
b2937 speB -0.8 -3.9 agmatinase (NCBI) compare
b2288 nuoA -0.8 -2.3 NADH dehydrogenase I chain A (VIMSS) compare
b1855 lpxM -0.8 -3.2 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b1785 yeaI -0.8 -1.0 predicted diguanylate cyclase (NCBI) compare
b3706 trmE -0.8 -1.9 tRNA modification GTPase (NCBI) compare
b4640 yoeG -0.8 -1.0 no description compare
b0781 moaA -0.8 -3.6 molybdenum cofactor biosynthesis protein A (NCBI) compare
b2369 evgA -0.8 -1.4 DNA-binding response regulator in two-component regulatory system with EvgS (NCBI) compare
b4402 yjjY -0.8 -0.6 hypothetical protein (NCBI) compare
b1108 ycfP -0.8 -1.7 orf, hypothetical protein (VIMSS) compare
b1847 yebF -0.8 -1.2 predicted protein (RefSeq) compare
b0460 hha -0.8 -2.5 modulator of gene expression, with H-NS (NCBI) compare
b1951 rcsA -0.8 -0.5 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b3446 yrhB -0.8 -2.7 hypothetical protein (NCBI) compare
b3631 rfaG -0.8 -5.6 glucosyltransferase I (NCBI) compare
b1292 sapC -0.8 -1.4 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1527 yneK -0.8 -1.2 hypothetical protein (NCBI) compare
b2313 cvpA -0.8 -2.7 membrane protein required for colicin V production (NCBI) compare
b2175 spr -0.8 -2.1 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b2501 ppk -0.8 -4.4 polyphosphate kinase (NCBI) compare
b0738 tolR -0.8 -1.3 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3164 pnp -0.8 -1.5 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b3630 rfaP -0.8 -4.2 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b1160 elbA -0.8 -0.5 hypothetical protein (NCBI) compare
b2804 fucU -0.7 -1.8 L-fucose mutarotase (NCBI) compare
b0908 aroA -0.7 -4.2 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b1298 ycjL -0.7 -1.7 probable amidotransferase subunit (VIMSS) compare
b1454 yncG -0.7 -1.4 predicted enzyme (NCBI) compare
b1196 ycgY -0.7 -1.4 hypothetical protein (NCBI) compare
b2085 b2085 -0.7 -1.8 orf, hypothetical protein (VIMSS) compare
b3792 wzxE -0.7 -3.4 O-antigen translocase (NCBI) compare
b1480 sra -0.7 -0.6 30S ribosomal subunit protein S22 (NCBI) compare
b0889 lrp -0.7 -2.0 DNA-binding transcriptional dual regulator, leucine-binding (NCBI) compare
b3860 dsbA -0.7 -4.0 periplasmic protein disulfide isomerase I (NCBI) compare
b1293 sapB -0.7 -0.9 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1630 rsxD -0.7 -3.2 electron transport complex protein RnfD (NCBI) compare
b2329 aroC -0.7 -2.8 chorismate synthase (NCBI) compare
b3790 rffC -0.7 -3.2 TDP-fucosamine acetyltransferase (RefSeq) compare
b4589 ylcI -0.7 -1.8 hypothetical protein (RefSeq) compare
b3493 pitA -0.7 -3.3 phosphate transporter, low-affinity (NCBI) compare
b2282 nuoH -0.7 -1.9 NADH dehydrogenase subunit H (NCBI) compare
b4634 ylcF -0.7 -3.1 no description compare
b3082 ygjM -0.7 -1.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b1028 ymdE -0.7 -2.1 orf, hypothetical protein (VIMSS) compare
b3778 rep -0.7 -3.3 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b1290 sapF -0.7 -1.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0237 pepD -0.7 -3.9 aminoacyl-histidine dipeptidase (peptidase D) (NCBI) compare
b1048 mdoG -0.7 -2.8 glucan biosynthesis protein, periplasmic (NCBI) compare
b3781 trxA -0.7 -2.1 thioredoxin 1 (VIMSS) compare
b1949 fliQ -0.7 -1.5 flagellar biosynthesis protein Q (NCBI) compare
b2325 yfcL -0.7 -1.9 hypothetical protein (NCBI) compare
b2343 b2343 -0.7 -1.2 orf, hypothetical protein (VIMSS) compare
b1588 ynfF -0.7 -2.1 oxidoreductase subunit (RefSeq) compare
b3794 rffM -0.7 -3.9 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b4240 treB -0.7 -4.7 fused trehalose(maltose)-specific PTS enzyme: IIB component/IIC component (NCBI) compare
b0014 dnaK -0.7 -1.1 molecular chaperone DnaK (NCBI) compare
b3153 yhbO -0.7 -2.6 orf, hypothetical protein (VIMSS) compare
b1693 aroD -0.7 -2.9 3-dehydroquinate dehydratase (NCBI) compare
b2456 cchB -0.7 -1.7 predicted carboxysome structural protein, ethanolamine utilization protein (NCBI) compare
b1613 manA -0.7 -1.2 mannose-6-phosphate isomerase (VIMSS) compare
b3349 slyD -0.7 -3.0 FKBP-type peptidyl prolyl cis-trans isomerase (rotamase) (NCBI) compare
b2490 b2490 -0.7 -1.9 putative protein processing element (VIMSS) compare
b4533 ynfO -0.7 -1.1 Qin prophage; predicted protein (NCBI) compare
b1126 potA -0.7 -3.3 putrescine/spermidine ABC transporter ATPase protein (NCBI) compare
b3806 cyaA -0.7 -2.5 adenylate cyclase (NCBI) compare
b2993 hybD -0.7 -2.4 predicted maturation element for hydrogenase 2 (NCBI) compare
b0610 rnk -0.7 -1.8 nucleoside diphosphate kinase regulator (NCBI) compare
b0463 acrA -0.7 -4.5 multidrug efflux system (NCBI) compare
b1634 tppB -0.7 -2.4 putative tripeptide transporter permease (NCBI) compare
b3408 feoA -0.7 -5.0 ferrous iron transport protein A (NCBI) compare
b1607 ydgC -0.7 -1.0 conserved inner membrane protein associated with alginate biosynthesis (NCBI) compare
b2510 b2510 -0.6 -2.4 orf, hypothetical protein (VIMSS) compare
b0364 yaiS -0.6 -1.2 orf, hypothetical protein (VIMSS) compare
b1309 ycjM -0.6 -1.5 putative polysaccharide hydrolase (VIMSS) compare
b3698 yidB -0.6 -2.8 orf, hypothetical protein (VIMSS) compare
b0890 ftsK -0.6 -1.3 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b3199 yrbK -0.6 -1.6 hypothetical protein (NCBI) compare
b2276 nuoN -0.6 -2.8 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b1379 hslJ -0.6 -2.1 heat-inducible protein (NCBI) compare
b2646 ypjF -0.6 -1.1 CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in stress experiments

For stress Spectinomycin dihydrochloride pentahydrate across organisms