Experiment set9IT024 for Escherichia coli BW25113

Compare to:

LB Anaerobic with Ceftriaxone disodium salt hemi(heptahydrate) 0.00000015625 mM

200 most important genes:

  gene name fitness t score description  
b1105 ycfM -5.8 -4.0 predicted outer membrane lipoprotein (NCBI) compare
b4392 slt -4.5 -16.0 soluble lytic murein transglycosylase (VIMSS) compare
b0149 mrcB -4.4 -6.1 penicillin-binding protein 1b (NCBI) compare
b1334 fnr -4.3 -2.9 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b1192 ldcA -3.8 -6.3 L,D-carboxypeptidase A (NCBI) compare
b4025 pgi -3.1 -9.2 glucose-6-phosphate isomerase (NCBI) compare
b0737 tolQ -3.0 -2.1 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0740 tolB -2.9 -2.0 translocation protein TolB precursor (NCBI) compare
b0741 pal -2.9 -3.4 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b0053 surA -2.9 -2.8 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b0381 ddlA -2.6 -8.8 D-alanylalanine synthetase (NCBI) compare
b0728 sucC -2.5 -6.9 succinyl-CoA synthetase subunit beta (NCBI) compare
b0433 ampG -2.5 -16.4 muropeptide transporter (NCBI) compare
b4237 nrdG -2.4 -11.0 anaerobic ribonucleotide reductase activating protein (NCBI) compare
b4238 nrdD -2.4 -15.2 anaerobic ribonucleoside triphosphate reductase (NCBI) compare
b0902 pflA -2.4 -8.5 pyruvate formate lyase activating enzyme 1 (NCBI) compare
b1103 ycfF -2.3 -2.1 orf, hypothetical protein (VIMSS) compare
b0903 pflB -2.2 -11.7 pyruvate formate lyase I (NCBI) compare
b0739 tolA -2.2 -1.5 cell envelope integrity inner membrane protein TolA (NCBI) compare
b4053 alr -2.1 -9.5 alanine racemase (NCBI) compare
b4402 yjjY -2.1 -1.4 hypothetical protein (NCBI) compare
b2258 b2258 -2.0 -2.1 putative transport/receptor protein (VIMSS) compare
b3792 wzxE -1.9 -5.8 O-antigen translocase (NCBI) compare
b0729 sucD -1.8 -4.1 succinyl-CoA synthetase subunit alpha (NCBI) compare
b1936 intG -1.8 -1.1 predicted defective phage integrase (pseudogene) (RefSeq) compare
b1346 ydaQ -1.7 -2.0 orf, hypothetical protein (VIMSS) compare
b3839 tatC -1.6 -6.2 TatABCE protein translocation system subunit (NCBI) compare
b0239 frsA -1.6 -8.4 fermentation/respiration switch protein (NCBI) compare
b2576 srmB -1.6 -2.6 ATP-dependent RNA helicase (NCBI) compare
b2363 yfdT -1.6 -1.7 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b0683 fur -1.6 -1.6 ferric uptake regulator (NCBI) compare
b0730 mngR -1.5 -1.0 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b0049 apaH -1.5 -2.6 diadenosinetetraphosphatase (NCBI) compare
b3930 menA -1.4 -10.9 1,4-dihydroxy-2-naphthoate octaprenyltransferase (NCBI) compare
b2620 smpB -1.3 -1.2 SsrA-binding protein (NCBI) compare
b0738 tolR -1.3 -1.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4201 priB -1.3 -2.5 primosomal replication protein N (NCBI) compare
b4535 yniD -1.3 -1.5 predicted protein (RefSeq) compare
b0434 yajG -1.3 -4.8 putative polymerase/proteinase (VIMSS) compare
b1361 ydaW -1.3 -0.6 orf, hypothetical protein (VIMSS) compare
b1677 lpp -1.2 -2.3 murein lipoprotein (NCBI) compare
b3164 pnp -1.2 -2.2 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b1493 gadB -1.2 -0.8 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b0783 moaC -1.2 -4.8 molybdenum cofactor biosynthesis protein C (NCBI) compare
b3229 sspA -1.2 -2.1 stringent starvation protein A (NCBI) compare
b0957 ompA -1.2 -3.2 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b1503 ydeR -1.1 -2.4 predicted fimbrial-like adhesin protein (NCBI) compare
b0623 cspE -1.1 -1.9 cold shock protein E (NCBI) compare
b0386 proC -1.1 -3.7 pyrroline-5-carboxylate reductase (NCBI) compare
b0145 dksA -1.1 -2.4 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b3838 tatB -1.1 -5.8 sec-independent translocase (NCBI) compare
b2083 yegZ -1.1 -2.0 orf, hypothetical protein (VIMSS) compare
b4577 sgrS -1.1 -1.3 small antisense RNA (NCBI) compare
b2553 glnB -1.0 -3.2 regulatory protein P-II for glutamine synthetase (NCBI) compare
b3857 mobA -1.0 -4.6 molybdopterin-guanine dinucleotide biosynthesis protein A (NCBI) compare
b0826 moeB -1.0 -5.0 molybdopterin biosynthesis protein MoeB (NCBI) compare
b0764 modB -1.0 -4.0 molybdate ABC transporter permease protein (NCBI) compare
b0009 mog -1.0 -5.4 molybdenum cofactor biosynthesis protein (NCBI) compare
b3916 pfkA -1.0 -1.6 6-phosphofructokinase (NCBI) compare
b0796 ybiH -1.0 -3.0 putative transcriptional regulator (VIMSS) compare
b1758 b1758 -1.0 -1.3 putative cytochrome oxidase (VIMSS) compare
b3052 rfaE -1.0 -3.5 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b0535 fimZ -1.0 -2.3 predicted DNA-binding transcriptional regulator (NCBI) compare
b2085 b2085 -1.0 -2.2 orf, hypothetical protein (VIMSS) compare
b1527 yneK -1.0 -1.3 hypothetical protein (NCBI) compare
b4042 dgkA -1.0 -1.7 diacylglycerol kinase (NCBI) compare
b1150 ymfR -1.0 -1.1 e14 prophage; predicted protein (NCBI) compare
b1429 tehA -1.0 -1.2 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b1506 yneL -0.9 -0.9 predicted transcriptional regulator (NCBI) compare
b0782 moaB -0.9 -1.4 molybdopterin biosynthesis protein B (NCBI) compare
b2424 cysU -0.9 -2.4 sulfate/thiosulfate transporter subunit (NCBI) compare
b3619 rfaD -0.9 -2.4 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b4613 dinQ -0.9 -1.3 Damage inducible, function unknown (RefSeq) compare
b0888 trxB -0.9 -2.1 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b1025 ycdT -0.9 -0.6 predicted diguanylate cyclase (NCBI) compare
b1850 eda -0.9 -1.7 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b0763 modA -0.9 -3.4 molybdate transporter subunit (NCBI) compare
b4181 yjfI -0.9 -1.9 hypothetical protein (NCBI) compare
b1161 ycgX -0.9 -0.7 hypothetical protein (NCBI) compare
b0232 yafN -0.9 -0.5 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b0142 folK -0.9 -0.4 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b0237 pepD -0.9 -4.5 aminoacyl-histidine dipeptidase (peptidase D) (NCBI) compare
b0051 ksgA -0.9 -2.3 dimethyladenosine transferase (NCBI) compare
b0949 uup -0.8 -4.4 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b2479 gcvR -0.8 -3.1 transcriptional regulation of gcv operon (VIMSS) compare
b0781 moaA -0.8 -4.7 molybdenum cofactor biosynthesis protein A (NCBI) compare
b1563 relE -0.8 -1.3 Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) compare
b2285 nuoE -0.8 -1.7 NADH dehydrogenase subunit E (NCBI) compare
b3764 yifE -0.8 -3.1 hypothetical protein (NCBI) compare
b1642 slyA -0.8 -1.4 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b3706 trmE -0.8 -2.2 tRNA modification GTPase (NCBI) compare
b0765 modC -0.8 -3.3 molybdate transporter subunit (NCBI) compare
b0113 pdhR -0.8 -2.9 transcriptional regulator of pyruvate dehydrogenase complex (NCBI) compare
b1292 sapC -0.8 -1.4 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0785 moaE -0.8 -2.9 molybdopterin synthase, large subunit (NCBI) compare
b3205 yhbJ -0.8 -2.3 hypothetical protein (NCBI) compare
b1600 mdtJ -0.8 -0.9 multidrug efflux system transporter (NCBI) compare
b3094 exuR -0.8 -3.3 negative regulator of exu regulon, exuT, uxaAC, and uxuB (VIMSS) compare
b2101 yegW -0.8 -3.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b2398 yfeC -0.8 -2.9 orf, hypothetical protein (VIMSS) compare
b0222 lpcA -0.8 -1.8 phosphoheptose isomerase (NCBI) compare
b1259 yciG -0.8 -1.2 orf, hypothetical protein (VIMSS) compare
b1279 yciS -0.8 -0.9 conserved inner membrane protein (NCBI) compare
b1160 elbA -0.8 -0.5 hypothetical protein (NCBI) compare
b3794 rffM -0.8 -4.1 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b2618 b2618 -0.7 -2.3 orf, hypothetical protein (VIMSS) compare
b3621 rfaC -0.7 -2.6 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b1482 osmC -0.7 -1.2 osmotically inducible, stress-inducible membrane protein (NCBI) compare
b3630 rfaP -0.7 -4.2 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b3836 b3836 -0.7 -2.7 orf, hypothetical protein (VIMSS) compare
b1861 ruvA -0.7 -0.4 Holliday junction DNA helicase motor protein (NCBI) compare
b3002 yqhA -0.7 -1.4 hypothetical protein (NCBI) compare
b3871 bipA -0.7 -4.8 GTP-binding protein (NCBI) compare
b1176 minC -0.7 -1.6 septum formation inhibitor (NCBI) compare
b3163 nlpI -0.7 -2.7 hypothetical protein (NCBI) compare
b1724 ydiZ -0.7 -1.5 hypothetical protein (NCBI) compare
b1968 yedV -0.7 -1.0 predicted sensory kinase in two-component regulatory system with YedW (NCBI) compare
b4648 ysaC -0.7 -1.8 no description compare
b0827 moeA -0.7 -2.9 molybdopterin biosynthesis protein (NCBI) compare
b1104 ycfL -0.7 -0.8 hypothetical protein (NCBI) compare
b3349 slyD -0.7 -3.6 FKBP-type peptidyl prolyl cis-trans isomerase (rotamase) (NCBI) compare
b3563 yiaB -0.7 -1.9 orf, hypothetical protein (VIMSS) compare
b3493 pitA -0.7 -3.3 phosphate transporter, low-affinity (NCBI) compare
b2369 evgA -0.7 -1.3 DNA-binding response regulator in two-component regulatory system with EvgS (NCBI) compare
b1686 ydiI -0.7 -1.0 hypothetical protein (NCBI) compare
b1841 yobA -0.7 -1.2 hypothetical protein (NCBI) compare
b1518 lsrG -0.7 -1.3 autoinducer-2 (AI-2) modifying protein LsrG (NCBI) compare
b3239 yhcO -0.7 -2.0 predicted barnase inhibitor (NCBI) compare
b1792 yeaO -0.7 -2.1 orf, hypothetical protein (VIMSS) compare
b4640 yoeG -0.7 -1.0 no description compare
b2498 upp -0.7 -1.6 uracil phosphoribosyltransferase (VIMSS) compare
b3620 rfaF -0.7 -2.5 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b4571 wbbL -0.7 -1.8 no description compare
b4505 insX -0.7 -0.5 predicted IS protein (RefSeq) compare
b2528 iscA -0.7 -1.0 iron-sulfur cluster assembly protein (NCBI) compare
b2912 ygfA -0.7 -1.6 putative ligase (VIMSS) compare
b3935 priA -0.7 -1.6 primosome assembly protein PriA (NCBI) compare
b2165 yeiN -0.7 -2.4 hypothetical protein (NCBI) compare
b1579 intQ -0.7 -1.0 Qin prophage; predicted defective integrase (RefSeq) compare
b1691 ydiN -0.6 -1.2 predicted transporter (RefSeq) compare
b3153 yhbO -0.6 -2.8 orf, hypothetical protein (VIMSS) compare
b2259 pmrD -0.6 -0.7 polymyxin resistance protein B (VIMSS) compare
b1335 ogt -0.6 -1.5 O-6-alkylguanine-DNA:cysteine-protein methyltransferase (NCBI) compare
b0364 yaiS -0.6 -1.2 orf, hypothetical protein (VIMSS) compare
b3631 rfaG -0.6 -4.8 glucosyltransferase I (NCBI) compare
b2263 yfbB -0.6 -1.9 predicted peptidase (NCBI) compare
b2274 yfbO -0.6 -2.0 predicted protein (RefSeq) compare
b3609 secB -0.6 -2.2 export protein SecB (NCBI) compare
b2168 fruK -0.6 -0.6 1-phosphofructokinase (NCBI) compare
b3387 dam -0.6 -4.2 DNA adenine methylase (NCBI) compare
b3396 mrcA -0.6 -5.4 peptidoglycan synthetase; penicillin-binding protein 1A (VIMSS) compare
b4215 ytfI -0.6 -0.4 hypothetical protein (NCBI) compare
b0685 ybfE -0.6 -1.6 orf, hypothetical protein (VIMSS) compare
b1108 ycfP -0.6 -1.6 orf, hypothetical protein (VIMSS) compare
b4545 ypdJ -0.6 -1.1 no description compare
b1860 ruvB -0.6 -0.3 Holliday junction DNA helicase B (NCBI) compare
b1241 adhE -0.6 -3.9 fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase (NCBI) compare
b1291 sapD -0.6 -0.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3226 yhcK -0.6 -2.3 putative FADA-type transcriptional regulator (VIMSS) compare
b3237 argR -0.6 -1.9 arginine repressor (NCBI) compare
b3786 rffE -0.6 -4.6 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b0784 moaD -0.6 -1.0 molybdopterin synthase, small subunit (NCBI) compare
b1290 sapF -0.6 -1.0 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1505 ydeT -0.6 -0.3 hypothetical protein (RefSeq) compare
b1773 ydjI -0.6 -0.7 predicted aldolase (NCBI) compare
b1877 yecT -0.6 -0.8 orf, hypothetical protein (VIMSS) compare
b4570 lomR -0.6 -1.1 no description compare
b1591 b1591 -0.6 -0.8 putative oxidoreductase component (VIMSS) compare
b3446 yrhB -0.6 -2.1 hypothetical protein (NCBI) compare
b3204 ptsN -0.6 -2.2 sugar-specific enzyme IIA component of PTS (NCBI) compare
b0122 yacC -0.6 -2.1 orf, hypothetical protein (VIMSS) compare
b1983 yeeN -0.6 -2.0 hypothetical protein (NCBI) compare
b1363 trkG -0.6 -0.3 Rac prophage; potassium transporter subunit (NCBI) compare
b1175 minD -0.5 -1.8 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b2506 yfgI -0.5 -1.2 hypothetical protein (NCBI) compare
b3778 rep -0.5 -2.7 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b1408 b1408 -0.5 -1.9 probable enzyme (VIMSS) compare
b0018 mokC -0.5 -0.7 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b4431 rprA -0.5 -1.0 Positive regulatory sRNA for RpoS translation; non-essential gene (RefSeq) compare
b4191 ulaR -0.5 -1.6 DNA-binding transcriptional dual regulator (NCBI) compare
b1330 ynaI -0.5 -1.6 conserved inner membrane protein (NCBI) compare
b0437 clpP -0.5 -2.3 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b3043 ygiL -0.5 -1.5 predicted fimbrial-like adhesin protein (NCBI) compare
b1690 ydiM -0.5 -0.6 predicted transporter (NCBI) compare
b4435 isrC -0.5 -1.2 unknown RNA (NCBI) compare
b4313 fimE -0.5 -2.8 tyrosine recombinase/inversion of on/off regulator of fimA (NCBI) compare
b3390 aroK -0.5 -0.8 shikimate kinase I (NCBI) compare
b3617 kbl -0.5 -2.8 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare
b2297 pta -0.5 -0.3 phosphate acetyltransferase (NCBI) compare
b2215 ompC -0.5 -3.2 outer membrane porin protein C (NCBI) compare
b4246 pyrL -0.5 -1.3 pyrBI operon leader peptide (NCBI) compare
b3408 feoA -0.5 -3.8 ferrous iron transport protein A (NCBI) compare
b1874 cutC -0.5 -0.8 copper homeostasis protein (NCBI) compare
b4503 yafF -0.5 -0.5 no description compare
b3613 yibP -0.5 -1.2 putative membrane protein (VIMSS) compare
b2510 b2510 -0.5 -2.0 orf, hypothetical protein (VIMSS) compare
b4418 sraB -0.5 -1.1 unknown RNA (NCBI) compare
b1454 yncG -0.5 -1.1 predicted enzyme (NCBI) compare
b4255 yjgD -0.5 -2.1 hypothetical protein (NCBI) compare
b3868 glnG -0.5 -2.0 fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) compare


Specific Phenotypes

For 3 genes in this experiment

For stress Ceftriaxone disodium salt hemi(heptahydrate) in Escherichia coli BW25113

For stress Ceftriaxone disodium salt hemi(heptahydrate) across organisms