Experiment set8S288 for Escherichia coli BL21

Compare to:

Control_TnJ

200 most detrimental genes:

  gene name fitness t score description  
ECD_01452 +1.6 2.9 putative periplasmic M16 family zinc metalloendopeptidase compare
ECD_03453 +1.4 3.1 DUF3302 family inner membrane protein compare
ECD_03999 +1.4 2.5 antitoxin of GhoTS toxin-antitoxin pair; endonuclease for ghoT mRNA compare
ECD_01763 +1.4 1.8 diguanylate cyclase compare
ECD_01472 +1.3 2.3 autoinducer 2 import system permease protein compare
ECD_01034 +1.2 2.2 curli production assembly/transport outer membrane lipoprotein compare
ECD_00807 +1.2 1.6 deoxyribose-5-phosphate-inducible deoxyribose operon transcriptional repressor; repressor of nupG and tsx compare
ECD_01774 +1.1 2.6 ribonuclease D compare
ECD_01253 +1.1 2.8 aconitate hydratase 1; aconitase A compare
ECD_03425 +1.1 1.1 putative hydrogenase, 4Fe-4S ferredoxin-type component compare
ECD_00993 +1.1 1.6 cold shock gene compare
ECD_02042 +1.1 1.9 DUF2574 family protein compare
ECD_03358 +1.0 1.5 stress response protein acid-resistance protein compare
ECD_01048 +1.0 1.2 multicopy suppressor of secY and secA compare
ECD_01852 +1.0 2.3 chemotaxis regulator, protein phosphatase for CheY compare
ECD_01273 +1.0 1.5 putrescine importer compare
ECD_00483 +1.0 3.3 FimA-like protein compare
ECD_01399 +1.0 1.9 putative ABC transporter permease compare
ECD_01706 +0.9 1.7 N,N'-diacetylchitobiose-specific enzyme IIC component of PTS compare
ECD_00487 +0.9 1.6 Excisionase compare
ECD_04308 +0.9 2.5 uncharacterized protein compare
ECD_02377 +0.9 2.1 hydrogenase 4, membrane subunit compare
ECD_00803 +0.9 1.6 repressor of biofilm formation by indole transport regulation compare
ECD_01405 +0.9 0.9 methionine N-acyltransferase; L-amino acid N-acyltransferase compare
ECD_00535 +0.8 2.8 copper/silver efflux system, membrane fusion protein compare
ECD_00752 +0.8 1.0 molybdopterin synthase, large subunit compare
ECD_01649 +0.8 2.1 cysteine desulfurase, stimulated by SufE; selenocysteine lyase, PLP-dependent compare
ECD_01188 +0.8 1.1 SIRB family inner membrane protein compare
ECD_01968 +0.8 2.7 colanic acid export protein; outer membrane auxillary lipoprotein compare
ECD_03093 +0.8 2.0 DUF1043 family inner membrane-anchored protein compare
ECD_00744 +0.8 2.4 malonyl-ACP O-methyltransferase, SAM-dependent compare
ECD_01001 +0.8 2.0 TorA-maturation chaperone compare
ECD_01951 +0.8 3.1 colanic acid biosynthesis protein compare
ECD_01812 +0.8 1.7 CopC family protein compare
ECD_01843 +0.8 3.1 trimethylamine N-oxide reductase system III, catalytic subunit compare
ECD_01573 +0.8 1.8 DUF1471 family periplasmic protein compare
ECD_00434 +0.8 1.2 putative DNA-binding transcriptional regulator compare
ECD_02090 +0.8 2.5 nucleoside permease compare
ECD_01650 +0.8 1.9 component of SufBCD Fe-S cluster assembly scaffold compare
ECD_01681 +0.8 1.2 integration host factor (IHF), DNA-binding protein, alpha subunit compare
ECD_00459 +0.8 1.7 tartronate semialdehyde reductase, NADH-dependent compare
ECD_04051 +0.7 1.5 UPF0719 family inner membrane protein compare
ECD_00455 +0.7 2.1 ureidoglycolate lyase, releasing urea compare
ECD_00506 +0.7 2.0 DLP12 prophage; putative phage lysis protein compare
ECD_01032 +0.7 1.7 redox enzyme maturation protein (REMP) chaperone for YcdX compare
ECD_00940 +0.7 1.4 aliphatic sulfonate ABC transporter periplasmic binding protein compare
ECD_02080 +0.7 1.8 galactose- and fucose-inducible galactose regulon transcriptional isorepressor; mgl operon transcriptional repressor; autorepressor compare
ECD_02345 +0.7 2.1 ethanolamine utilization protein, HSP70/actin superfamily protein compare
ECD_00480 +0.7 1.3 FimA-like protein compare
ECD_01031 +0.7 2.2 alkaline phosphatase compare
ECD_02473 +0.7 1.5 autonomous glycyl radical cofactor compare
ECD_02162 +0.7 1.0 ferredoxin involved with ribonucleotide reductase diferric-tyrosyl radical (Y*) cofactor maintenance compare
ECD_02032 +0.7 1.6 hydoxyethylthiazole kinase compare
ECD_02348 +0.7 1.2 ethanolamine utilization protein, putative carboxysome structural protein compare
ECD_03023 +0.7 2.0 GNAT family putative N-acetyltransferase compare
ECD_01320 +0.7 1.6 ATP-dependent RNA helicase, specific for 23S rRNA compare
ECD_01957 +0.7 1.2 GDP-mannose mannosyl hydrolase compare
ECD_01667 +0.7 1.3 putative electron transfer flavoprotein, FAD-binding subunit compare
ECD_02287 +0.7 1.0 DUF2545 family putative inner membrane protein compare
ECD_03695 +0.7 0.9 Magnesium and cobalt transport protein corA compare
ECD_01163 +0.7 2.2 SpoVR family stationary phase protein compare
ECD_01435 +0.7 0.9 putative DNA-binding transcriptional regulator compare
ECD_00995 +0.7 2.3 putative 4Fe-4S membrane protein compare
ECD_00834 +0.6 1.4 putative capsid scaffolding protein compare
ECD_02825 +0.6 1.1 Pyrophosphorylase compare
ECD_02058 +0.6 1.2 putative ABC transporter permease compare
ECD_01221 +0.6 1.5 oligopeptide ABC transporter ATPase compare
ECD_01801 +0.6 4.5 carboxy-terminal protease for penicillin-binding protein 3 compare
ECD_01486 +0.6 1.1 UPF0056 family inner membrane protein compare
ECD_02732 +0.6 0.8 UPF0267 family protein compare
ECD_00399 +0.6 1.3 putative DNA-binding transcriptional regulator compare
ECD_00813 +0.6 1.1 transcriptional regulator of csgD and ybiJI; autoregulator compare
ECD_02122 +0.6 1.3 periplasmic thioredoxin of cytochrome c-type biogenesis compare
ECD_03774 +0.6 0.9 CopG family putative transcriptional regulator compare
ECD_03350 +0.6 0.8 arsenical resistance operon transcriptional repressor; autorepressor compare
ECD_02169 +0.6 2.3 anaerobic sn-glycerol-3-phosphate dehydrogenase, C subunit, 4Fe-4S iron-sulfur cluster compare
ECD_01912 +0.6 1.6 DNA gyrase inhibitor compare
ECD_00706 +0.6 1.3 putative periplasmic protein compare
ECD_01575 +0.6 1.0 dihydromonapterin reductase, NADPH-dependent; dihydrofolate reductase isozyme compare
ECD_00011 +0.6 1.6 UPF0174 family protein compare
ECD_01403 +0.6 0.7 DUF2526 family protein compare
ECD_01068 +0.6 1.3 assembly protein for flagellar basal-body periplasmic P ring compare
ECD_03660 +0.6 0.9 rho operon leader peptide compare
ECD_01589 +0.6 0.9 transcriptional repressor of Mal regulon compare
ECD_02048 +0.6 1.2 putative hexameric AAA+ MoxR family ATPase compare
ECD_00261 +0.5 1.7 reactive chlorine species (RCS)-specific activator of the rcl genes compare
ECD_01584 +0.5 1.5 putative outer membrane porin for beta-glucuronides porin protein compare
ECD_01374 +0.5 1.3 cytochrome b561 compare
ECD_01061 +0.5 1.4 multidrug resistance efflux transporter conferring overexpression resistance to norfloxacin and enoxacin compare
ECD_00531 +0.5 1.8 copper-sensing histidine kinase in two-component regulatory system with CusR compare
ECD_02397 +0.5 1.3 outer membrane integrity lipoprotein compare
ECD_00779 +0.5 1.0 Fe-binding and storage protein; stress-inducible DNA-binding protein compare
ECD_01979 +0.5 1.5 multidrug efflux system, subunit A compare
ECD_03433 +0.5 2.4 3-keto-L-gulonate 6-phosphate decarboxylase compare
ECD_00745 +0.5 1.8 dethiobiotin synthetase compare
ECD_02278 +0.5 1.5 multidrug resistance efflux pump membrane fusion protein compare
ECD_01101 +0.5 1.0 OM lipoprotein stimulator of MrcB transpeptidase compare
ECD_02305 +0.5 1.2 DUF1323 family putative DNA-binding protein compare
ECD_02343 +0.5 1.9 ethanolamine transporter compare
ECD_00978 +0.5 1.1 hydrogenase 1 maturation protease compare
ECD_00276 +0.5 1.8 putative NAD(P)-binding succinyl-CoA synthase compare
ECD_02582 +0.5 1.8 uncharacterized protein compare
ECD_00801 +0.5 1.2 putative membrane-anchored diguanylate cyclase compare
ECD_01302 +0.5 1.3 L-Ala-D/L-Glu epimerase compare
ECD_01015 +0.5 1.9 pyrimidine oxygenase, FMN-dependent compare
ECD_00432 +0.5 0.9 Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase compare
ECD_01102 +0.5 1.9 thiamine kinase compare
ECD_00441 +0.5 1.3 iron export ABC transporter ATPase; peroxide resistance protein compare
ECD_03966 +0.5 1.9 ribose 1,5-bisphosphokinase compare
ECD_00655 +0.5 1.3 potassium translocating ATPase, subunit A compare
ECD_01786 +0.5 1.6 putative membrane protein/conserved protein compare
ECD_01022 +0.5 1.2 ATP-binding protein; putative PhoH family P-loop ATPase compare
ECD_02300 +0.5 1.6 DUF2502 family putative periplasmic protein compare
ECD_00878 +0.5 1.7 hybrid-cluster [4Fe-2S-2O] subunit of anaerobic terminal reductases compare
ECD_01093 +0.5 1.9 septation protein, ampicillin sensitivity compare
ECD_01404 +0.5 1.1 DUF606 family inner membrane protein compare
ECD_01281 +0.5 2.0 regulatory protein for phage-shock-protein operon compare
ECD_04079 +0.5 1.6 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) compare
ECD_01795 +0.5 1.5 putative inner membrane protein compare
ECD_02192 +0.5 1.2 isochorismate synthase 2 compare
ECD_03403 +0.5 2.0 glyoxylate/hydroxypyruvate reductase B compare
ECD_00050 +0.5 1.4 potassium-efflux system ancillary protein for KefC, glutathione-regulated; quinone oxidoreductase, FMN-dependent compare
ECD_00484 +0.5 0.9 FimA-like protein compare
ECD_01274 +0.5 1.7 glutamate--putrescine ligase compare
ECD_02862 +0.5 2.1 putative ATP-binding protein compare
ECD_00040 +0.5 1.6 carnitinyl-CoA dehydratase compare
ECD_04273 +0.5 1.8 putative periplasmic protein compare
ECD_01488 +0.5 0.6 putative phage protein compare
ECD_03530 +0.5 0.7 hypothetical protein compare
ECD_00832 +0.5 1.7 putative capsid portal protein compare
ECD_03541 +0.5 1.0 hypothetical protein compare
ECD_04193 +0.4 0.8 fructuronate-inducible hexuronate regulon transcriptional repressor; autorepressor compare
ECD_02665 +0.4 3.2 N-acetylmuramoyl-L-alanine amidase compare
ECD_00335 +0.4 1.1 shikimate kinase II compare
ECD_02444 +0.4 2.4 fused nitric oxide dioxygenase/dihydropteridine reductase 2 compare
ECD_02051 +0.4 2.0 hypothetical protein compare
ECD_02167 +0.4 1.6 anaerobic sn-glycerol-3-phosphate dehydrogenase, large FAD/NAD(P)-binding subunit compare
ECD_03338 +0.4 1.7 DUF4049 family protein compare
ECD_04221 +0.4 2.2 4-hydroxyphenylacetate 3-monooxygenase, reductase component compare
ECD_03022 +0.4 1.1 GIY-YIG nuclease superfamily protein compare
ECD_01409 +0.4 1.1 ATP-binding protein, periplasmic, function unknown compare
ECD_01785 +0.4 1.2 putative membrane-anchored cyclic-di-GMP phosphodiesterase, regulator of cellulose production compare
ECD_02231 +0.4 1.2 histidine ABC transporter ATPase compare
ECD_02250 +0.4 0.5 uncharacterized protein compare
ECD_01784 +0.4 1.6 L-serine dehydratase 1 compare
ECD_00900 +0.4 1.0 dimethyl sulfoxide reductase, anaerobic, subunit C compare
ECD_02994 +0.4 2.4 antitoxin of the SohA(PrlF)-YhaV toxin-antitoxin system compare
ECD_02384 +0.4 1.0 putative formate transporter compare
ECD_01478 +0.4 0.6 altronate oxidoreductase, NAD-dependent compare
ECD_00533 +0.4 0.7 copper/silver efflux system, outer membrane component compare
ECD_01370 +0.4 0.5 aldehyde dehydrogenase A, NAD-linked compare
ECD_02135 +0.4 1.2 ferredoxin-type protein, role in electron transfer to periplasmic nitrate reductase NapA compare
ECD_01802 +0.4 2.3 RNA chaperone, putative ProP translation regulator compare
ECD_00616 +0.4 1.5 Hsp70 family chaperone Hsc62; RpoD-binding transcription inhibitor compare
ECD_01561 +0.4 0.8 H(+)/Cl(-) exchange transporter compare
ECD_02915 +0.4 0.6 putative fimbrial-like adhesin protein compare
ECD_04249 +0.4 1.9 dUMP phosphatase compare
ECD_01693 +0.4 1.1 uncharacterized protein compare
ECD_01445 +0.4 1.0 D,D-dipeptide ABC transporter periplasmic binding protein compare
ECD_01305 +0.4 1.0 S9-like protein non-peptidase family protein compare
ECD_02349 +0.4 0.8 phosphate acetyltransferase compare
ECD_02658 +0.4 2.4 UPF0382 family inner membrane protein compare
ECD_01634 +0.4 0.9 multidrug efflux system transporter compare
ECD_01443 +0.4 0.8 D,D-dipeptide ABC transporter permease compare
ECD_00004 +0.4 1.7 L-threonine synthase compare
ECD_02132 +0.4 0.8 ferredoxin-type protein compare
ECD_01866 +0.4 1.3 trehalose-6-phosphate phosphatase, biosynthetic compare
ECD_02308 +0.4 1.3 transcriptional regulator of yefH compare
ECD_03180 +0.4 1.2 putative general secretory pathway component, cryptic compare
ECD_01716 +0.4 0.9 arginine succinyltransferase compare
ECD_01097 +0.4 1.5 fused glucose-specific PTS enzymes: IIB component/IIC component compare
ECD_01865 +0.4 1.0 trehalose-6-phosphate synthase compare
ECD_00137 +0.4 1.5 putative fimbrial-like adhesin protein compare
ECD_02258 +0.4 0.8 putative fimbrial-like adhesin protein compare
ECD_01300 +0.4 1.3 aromatic amino acid biosynthesis and transport regulon transcriptional regulator; autorepressor; ATPase; phosphatase compare
ECD_01492 +0.4 0.8 cysteine and O-acetyl-L-serine efflux system compare
ECD_00205 +0.4 1.7 hydroxyacylglutathione hydrolase compare
ECD_00231 +0.4 0.8 peptide chain release factor 2 compare
ECD_01126 +0.4 1.2 50S ribosomal protein L16 arginine hydroxylase; 2-oxoglutarate oxygenase compare
ECD_02072 +0.4 1.5 cytidine/deoxycytidine deaminase compare
ECD_04242 +0.4 1.3 putative transcriptional regulator compare
ECD_02919 +0.4 0.9 motility and biofilm regulator compare
ECD_02067 +0.4 1.2 putative oxidoreductase compare
ECD_00394 +0.4 1.4 putative competence-suppressing periplasmic helix-hairpin-helix DNA-binding protein compare
ECD_02152 +0.4 1.2 DUF2135 family protein, putative host defense protein compare
ECD_03217 +0.4 0.9 nitrite reductase (NADH) small subunit compare
ECD_01954 +0.4 0.5 phosphomannomutase compare
ECD_00439 +0.4 0.8 inner membrane protein; stimulator of the QmcA suppressor of ftsH-htpX compare
ECD_00756 +0.4 1.8 cardiolipin synthase 2 compare
ECD_01064 +0.4 1.0 putative oxidoreductase compare
ECD_01955 +0.4 1.5 mannose-1-phosphate guanyltransferase compare
ECD_00658 +0.4 1.1 Rhs protein with putative toxin domain; putative neighboring cell growth inhibitor compare
ECD_00139 +0.4 1.3 putative periplasmic pilin chaperone compare
ECD_00945 +0.4 1.6 putative fimbrial-like adhesin protein compare
ECD_01427 +0.4 0.8 nitrate/nitrite transporter compare
ECD_02103 +0.4 0.8 Zn-stimulated GTPase involved in zinc homeostasis; mutants are cadmium and EDTA sensitive; Zn(2+) binding protein compare
ECD_02912 +0.4 1.5 zinc transporter compare
ECD_03659 +0.4 0.5 thioredoxin 1 compare
ECD_04152 +0.4 1.5 hypothetical protein compare
ECD_00430 +0.4 1.7 putative fosmidomycin efflux system protein compare


Specific Phenotypes

None in this experiment

For Escherichia coli BL21 in no phage control experiments