Experiment set8S122 for Escherichia coli ECOR27

Compare to:

Mpec13

200 most important genes:

  gene name fitness t score description  
NOLOHH_17630 btuD -4.8 -3.3 vitamin B12 ABC transporter ATP-binding protein BtuD compare
NOLOHH_00385 -4.3 -2.5 hypothetical protein compare
NOLOHH_05490 hupA -4.1 -2.8 DNA-binding protein HU-alpha compare
NOLOHH_06550 xerC -3.5 -3.4 tyrosine recombinase XerC compare
NOLOHH_00170 -3.5 -1.5 hypothetical protein compare
NOLOHH_07575 rfaF -3.5 -2.4 ADP-heptose--LPS heptosyltransferase RfaF compare
NOLOHH_20460 galU -3.5 -3.3 UTP--glucose-1-phosphate uridylyltransferase GalU compare
NOLOHH_23310 odhB -3.0 -2.9 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase compare
NOLOHH_06530 corA -3.0 -5.3 magnesium/cobalt transporter CorA compare
NOLOHH_11425 ubiI -2.8 -2.7 FAD-dependent 2-octaprenylphenol hydroxylase compare
NOLOHH_21130 yceD -2.7 -3.7 23S rRNA accumulation protein YceD compare
NOLOHH_13310 hscA -2.7 -3.1 Fe-S protein assembly chaperone HscA compare
NOLOHH_07125 -2.5 -4.4 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE compare
NOLOHH_09400 Thr_trna -2.4 -2.5 tRNA-Thr(ggt) compare
NOLOHH_17835 -2.2 -1.5 Ferredoxin compare
NOLOHH_20735 fadR -2.2 -2.1 fatty acid metabolism transcriptional regulator FadR compare
NOLOHH_05815 metL -2.1 -10.0 bifunctional aspartate kinase/homoserine dehydrogenase II compare
NOLOHH_06920 mnmG -2.1 -5.9 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG compare
NOLOHH_14340 ubiX -2.1 -2.8 flavin prenyltransferase UbiX compare
NOLOHH_23250 tolR -2.1 -3.3 colicin uptake protein TolR compare
NOLOHH_13055 rseA -2.1 -2.7 anti-sigma-E factor RseA compare
NOLOHH_23510 fur -2.1 -2.6 ferric iron uptake transcriptional regulator compare
NOLOHH_03190 apaH -2.0 -6.8 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH compare
NOLOHH_02845 aceE -2.0 -1.9 pyruvate dehydrogenase (acetyl-transferring), homodimeric type compare
NOLOHH_24695 vapB -2.0 -2.1 toxin-antitoxin system antitoxin VapB compare
NOLOHH_19350 mokB -2.0 -2.5 IS3 family transposase compare
NOLOHH_23315 sucA -2.0 -1.5 2-oxoglutarate dehydrogenase E1 component compare
NOLOHH_15160 yohP -1.9 -1.6 protein YohP compare
NOLOHH_20185 rnb -1.9 -2.5 exoribonuclease II compare
NOLOHH_09730 ptsN -1.9 -2.7 PTS IIA-like nitrogen regulatory protein PtsN compare
NOLOHH_11775 yqeJ -1.9 -1.1 Uncharacterized protein YqeJ compare
NOLOHH_23480 pgm -1.9 -3.9 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) compare
NOLOHH_18070 rsxB -1.8 -2.4 electron transport complex subunit RsxB compare
NOLOHH_06755 ppiC -1.8 -1.9 peptidylprolyl isomerase PpiC compare
NOLOHH_07535 rfaG -1.8 -6.0 Lipopolysaccharide core biosynthesis protein RfaG compare
NOLOHH_24675 finO -1.8 -6.6 Fertility inhibition protein compare
NOLOHH_04525 miaA -1.8 -1.5 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA compare
NOLOHH_13865 crr -1.8 -1.8 PTS glucose transporter subunit IIA compare
NOLOHH_23030 -1.8 -2.3 siphovirus Gp157 family protein compare
NOLOHH_06665 wzyE -1.8 -6.3 ECA oligosaccharide polymerase compare
NOLOHH_09835 obgE -1.7 -1.6 GTPase ObgE compare
NOLOHH_14520 nuoN -1.6 -5.0 NADH-quinone oxidoreductase subunit NuoN compare
NOLOHH_20785 ycgL -1.6 -2.4 Protein YcgL compare
NOLOHH_17125 rnd -1.6 -2.0 ribonuclease D compare
NOLOHH_21500 -1.6 -1.8 hypothetical protein compare
NOLOHH_00605 essD -1.6 -2.9 phage lysis protein EssD compare
NOLOHH_17810 pykF -1.6 -2.7 pyruvate kinase PykF compare
NOLOHH_18305 ynfA -1.6 -1.2 YnfA family protein compare
NOLOHH_11365 rpiA -1.5 -2.1 ribose-5-phosphate isomerase RpiA compare
NOLOHH_16310 fliM -1.5 -2.0 flagellar motor switch protein FliM compare
NOLOHH_11495 xerD -1.5 -2.5 site-specific tyrosine recombinase XerD compare
NOLOHH_18935 digH -1.5 -1.5 Glycosyl hydrolase DigH compare
NOLOHH_07550 rfaY -1.5 -6.4 lipopolysaccharide core heptose(II) kinase RfaY compare
NOLOHH_23495 ybfE -1.5 -2.9 LexA regulated protein compare
NOLOHH_02825 acnB -1.5 -2.2 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase compare
NOLOHH_05830 metJ -1.5 -1.7 met regulon transcriptional regulator MetJ compare
NOLOHH_16355 yedK -1.4 -1.6 Abasic site processing protein YedK compare
NOLOHH_09695 arcB -1.4 -5.0 aerobic respiration two-component sensor histidine kinase ArcB compare
NOLOHH_16500 yecJ -1.4 -1.9 Uncharacterized protein YecJ compare
NOLOHH_20895 nudJ -1.4 -1.1 phosphatase NudJ compare
NOLOHH_03170 surA -1.4 -3.9 peptidylprolyl isomerase SurA compare
NOLOHH_13070 rseC -1.4 -3.9 SoxR-reducing system protein RseC compare
NOLOHH_24815 trbG -1.4 -1.1 conjugal transfer protein TrbG compare
NOLOHH_07540 rfaP -1.3 -5.7 lipopolysaccharide core heptose(I) kinase RfaP compare
NOLOHH_13640 arsC -1.3 -2.5 ArsC family reductase compare
NOLOHH_24470 -1.3 -1.1 prepilin-type cleavage/methylation domain-containing protein compare
NOLOHH_21050 -1.3 -1.3 DUF1425 domain-containing protein compare
NOLOHH_13115 shoB -1.3 -1.2 Small toxic protein ShoB compare
NOLOHH_13300 iscA -1.3 -1.3 iron-sulfur cluster assembly protein IscA compare
NOLOHH_06675 wzxE -1.3 -3.7 lipid III flippase WzxE compare
NOLOHH_00705 gam -1.3 -2.8 Host-nuclease inhibitor protein gam compare
NOLOHH_09590 argR -1.3 -3.1 transcriptional regulator ArgR compare
NOLOHH_20455 hns -1.3 -2.4 DNA-binding transcriptional regulator H-NS compare
NOLOHH_14475 nuoE -1.3 -1.3 NADH-quinone oxidoreductase subunit NuoE compare
NOLOHH_20465 rssB -1.3 -2.0 two-component system response regulator RssB compare
NOLOHH_05225 dgkA -1.2 -3.4 diacylglycerol kinase compare
NOLOHH_14510 nuoL -1.2 -5.2 NADH-quinone oxidoreductase subunit L compare
NOLOHH_23485 seqA -1.2 -1.4 replication initiation negative regulator SeqA compare
NOLOHH_11415 pepP -1.2 -4.5 Xaa-Pro aminopeptidase compare
NOLOHH_14305 truA -1.2 -3.6 tRNA pseudouridine(38-40) synthase TruA compare
NOLOHH_16845 zwf -1.2 -1.2 glucose-6-phosphate dehydrogenase compare
NOLOHH_04005 Leu_trna -1.2 -1.3 tRNA-Leu(caa) compare
NOLOHH_11245 -1.2 -1.2 Putative oxidoreductase compare
NOLOHH_15485 yegS -1.2 -2.0 lipid kinase YegS compare
NOLOHH_18240 ynfL -1.2 -1.6 Uncharacterized HTH-type transcriptional regulator YnfL compare
NOLOHH_19485 paaB -1.1 -1.2 1,2-phenylacetyl-CoA epoxidase subunit B compare
NOLOHH_24495 -1.1 -0.8 lngG compare
NOLOHH_14505 nuoK -1.1 -2.3 NADH-quinone oxidoreductase subunit NuoK compare
NOLOHH_14485 nuoG -1.1 -4.9 NADH-quinone oxidoreductase subunit NuoG compare
NOLOHH_08720 glpD -1.1 -4.9 glycerol-3-phosphate dehydrogenase compare
NOLOHH_00600 rrrD -1.1 -3.2 lysozyme RrrD compare
NOLOHH_14160 Arg_trna -1.1 -3.3 tRNA-Arg(cct) compare
NOLOHH_18060 rsxD -1.1 -2.6 electron transport complex subunit RsxD compare
NOLOHH_05965 pfkA -1.1 -3.8 6-phosphofructokinase compare
NOLOHH_14470 nuoC -1.1 -4.4 NADH-quinone oxidoreductase subunit C/D compare
NOLOHH_17170 insQ -1.1 -1.1 Putative RNA-guided DNA endonuclease InsQ compare
NOLOHH_18080 ydgK -1.1 -1.4 Inner membrane protein YdgK compare
NOLOHH_21890 ssuE -1.1 -1.3 NADPH-dependent FMN reductase compare
NOLOHH_09455 -1.1 -1.7 DUF2556 domain-containing protein compare
NOLOHH_08900 aroK -1.1 -1.2 shikimate kinase AroK compare
NOLOHH_00620 -1.1 -1.4 Orf33, orf151, orf56, orf96, rus, orf45, orf8, orf127, and nmpC genes compare
NOLOHH_00525 -1.1 -1.0 Tail tube terminator protein compare
NOLOHH_14515 nuoM -1.1 -4.0 NADH-quinone oxidoreductase subunit M compare
NOLOHH_09940 pnp -1.1 -5.3 polyribonucleotide nucleotidyltransferase compare
NOLOHH_01255 lon_P403L -1.0 -5.0 Lon protease compare
NOLOHH_11230 tkt -1.0 -1.8 transketolase compare
NOLOHH_19330 ydcJ -1.0 -1.1 Uncharacterized protein YdcJ compare
NOLOHH_09610 zapG -1.0 -3.6 Z-ring associated protein ZapG compare
NOLOHH_08775 -1.0 -3.4 NfuA family Fe-S biogenesis protein compare
NOLOHH_17705 ydiO -1.0 -2.1 acyl-CoA dehydrogenase compare
NOLOHH_23245 tolA -1.0 -3.4 cell envelope integrity protein TolA compare
NOLOHH_22880 -1.0 -4.9 phage holin, lambda family compare
NOLOHH_23240 tolB -1.0 -4.6 Tol-Pal system protein TolB compare
NOLOHH_22910 ninG -1.0 -2.8 Protein ninG compare
NOLOHH_00445 -1.0 -1.6 peptidyl-arginine deiminase compare
NOLOHH_11120 yggT -1.0 -1.1 osmotic shock tolerance protein YggT compare
NOLOHH_20865 bluF -1.0 -1.0 blue light-responsive regulator BluF compare
NOLOHH_19845 recT -0.9 -1.4 recombination protein RecT compare
NOLOHH_00565 -0.9 -1.1 Lambda prophage-derived head-to-tail joining protein W compare
NOLOHH_07015 pstC -0.9 -1.6 phosphate ABC transporter permease PstC compare
NOLOHH_09760 kdsC -0.9 -3.0 3-deoxy-manno-octulosonate-8-phosphatase KdsC compare
NOLOHH_14480 nuoF -0.9 -4.0 NADH-quinone oxidoreductase subunit NuoF compare
NOLOHH_14490 nuoH -0.9 -2.9 NADH-quinone oxidoreductase subunit NuoH compare
NOLOHH_02285 hcp1,tssD1 -0.9 -1.2 type VI secretion system protein, Hcp family compare
NOLOHH_10800 hybD -0.9 -3.1 HyaD/HybD family hydrogenase maturation endopeptidase compare
NOLOHH_02630 yadW -0.9 -1.2 Protein YadW compare
NOLOHH_11515 lysS -0.9 -1.7 lysine--tRNA ligase compare
NOLOHH_06540 uvrD -0.9 -6.6 DNA helicase II compare
NOLOHH_18900 ydeN -0.9 -1.1 Uncharacterized sulfatase YdeN compare
NOLOHH_14500 nuoJ -0.9 -2.7 NADH-quinone oxidoreductase subunit J compare
NOLOHH_21740 rlmI -0.9 -3.0 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI compare
NOLOHH_15970 -0.9 -1.8 microcompartment protein compare
NOLOHH_18225 ydgU -0.9 -0.9 Uncharacterized protein YdgU compare
NOLOHH_14455 -0.9 -1.0 hypothetical protein compare
NOLOHH_03030 cra -0.9 -4.1 catabolite repressor/activator compare
NOLOHH_22835 -0.9 -2.6 hypothetical protein compare
NOLOHH_11490 fldB -0.9 -4.0 flavodoxin FldB compare
NOLOHH_23160 galM -0.9 -1.8 galactose-1-epimerase compare
NOLOHH_06250 hemN -0.9 -5.5 oxygen-independent coproporphyrinogen III oxidase compare
NOLOHH_21940 aspC -0.9 -1.5 aspartate transaminase compare
NOLOHH_00315 -0.8 -1.9 Cnjugal protein Pilx7 compare
NOLOHH_06805 maoP -0.8 -5.7 macrodomain Ori organization protein MaoP compare
NOLOHH_24235 -0.8 -0.8 conjugal transfer protein TraM compare
NOLOHH_18675 ydeE -0.8 -1.6 efflux MFS transporter YdeE compare
NOLOHH_16535 uspC -0.8 -1.8 universal stress protein UspC compare
NOLOHH_06385 fre -0.8 -5.0 NAD(P)H-flavin reductase compare
NOLOHH_21490 efeU -0.8 -1.2 Ferrous iron permease EfeU compare
NOLOHH_24755 -0.8 -0.7 toxin ArtA compare
NOLOHH_17385 ynjC -0.8 -2.9 Inner membrane ABC transporter permease protein YnjC compare
NOLOHH_21555 wrbA -0.8 -1.6 NAD(P)H:quinone oxidoreductase compare
NOLOHH_02450 yaeP -0.8 -3.1 YaeP family protein compare
NOLOHH_19165 vgrG,tssI -0.8 -2.2 type VI secretion system effector VgrG compare
NOLOHH_19305 tehA -0.8 -1.1 dicarboxylate transporter/tellurite-resistance protein TehA compare
NOLOHH_00515 -0.8 -3.7 Phage minor tail protein G compare
NOLOHH_15125 preT -0.8 -1.7 NAD-dependent dihydropyrimidine dehydrogenase subunit PreT compare
NOLOHH_20820 ymgG -0.8 -0.8 UPF0757 protein YmgG compare
NOLOHH_15015 fruB -0.8 -2.3 fused PTS fructose transporter subunit IIA/HPr protein compare
NOLOHH_21710 hyaB -0.8 -2.4 Ni/Fe-hydrogenase large subunit compare
NOLOHH_05335 pgi -0.8 -5.0 glucose-6-phosphate isomerase compare
NOLOHH_17545 yniA -0.8 -1.2 putative ketoamine kinase YniA compare
NOLOHH_00720 -0.8 -2.7 cruciferin compare
NOLOHH_17225 dgcJ -0.8 -1.5 diguanylate cyclase DgcJ compare
NOLOHH_23300 sucD -0.8 -3.7 succinate--CoA ligase subunit alpha compare
NOLOHH_02090 yafP -0.8 -3.6 GNAT family N-acetyltransferase compare
NOLOHH_22905 ninH -0.8 -1.6 Protein ninH compare
NOLOHH_00560 -0.8 -1.2 phage portal protein compare
NOLOHH_00760 fimZ -0.8 -0.9 fimbria biosynthesis transcriptional regulator FimZ compare
NOLOHH_02690 dksA -0.8 -2.6 RNA polymerase-binding protein DksA compare
NOLOHH_00360 -0.8 -4.0 relaxase/mobilization nuclease compare
NOLOHH_00790 fimA -0.8 -1.3 type 1 fimbrial major subunit FimA compare
NOLOHH_06730 trxA -0.8 -2.3 thioredoxin TrxA compare
NOLOHH_17270 yeaC -0.8 -1.0 Uncharacterized protein YeaC compare
NOLOHH_06810 hdfR -0.7 -5.2 HTH-type transcriptional regulator HdfR compare
NOLOHH_19930 abgT -0.7 -3.3 p-aminobenzoyl-glutamate transporter compare
NOLOHH_13185 glyA -0.7 -2.8 serine hydroxymethyltransferase compare
NOLOHH_09955 deaD -0.7 -2.3 ATP-dependent RNA helicase DeaD compare
NOLOHH_13595 vapB -0.7 -2.2 toxin-antitoxin system antitoxin VapB compare
NOLOHH_09845 greA -0.7 -1.0 transcription elongation factor GreA compare
NOLOHH_06585 cyaY -0.7 -3.0 iron donor protein CyaY compare
NOLOHH_16870 yebF -0.7 -1.5 Protein YebF compare
NOLOHH_08905 aroB -0.7 -2.9 3-dehydroquinate synthase compare
NOLOHH_01270 clpP -0.7 -1.5 ATP-dependent Clp endopeptidase proteolytic subunit ClpP compare
NOLOHH_15245 yehR -0.7 -1.7 Uncharacterized lipoprotein YehR compare
NOLOHH_15000 yeiW -0.7 -1.0 UPF0153 protein YeiW compare
NOLOHH_08145 bcsZ -0.7 -4.2 cellulose synthase complex periplasmic endoglucanase BcsZ compare
NOLOHH_02485 rnhB -0.7 -1.3 ribonuclease HII compare
NOLOHH_20905 hflD -0.7 -1.1 high frequency lysogenization protein HflD compare
NOLOHH_24370 -0.7 -1.0 hypothetical protein compare
NOLOHH_21510 rutR -0.7 -2.4 HTH-type transcriptional regulator RutR compare
NOLOHH_07310 tisB -0.7 -1.6 Small toxic protein TisB compare
NOLOHH_00520 -0.7 -2.4 Tail tube protein compare
NOLOHH_15555 -0.7 -1.7 Type I toxin-antitoxin system Ibs family toxin compare
NOLOHH_08510 ftsE -0.7 -2.0 cell division ATP-binding protein FtsE compare
NOLOHH_21310 msyB -0.7 -1.3 MysB family protein compare
NOLOHH_07010 pstS -0.7 -3.9 phosphate ABC transporter substrate-binding protein PstS compare
NOLOHH_14450 lrhA -0.7 -4.0 transcriptional regulator LrhA compare
NOLOHH_16010 pduA -0.7 -1.7 propanediol utilization microcompartment protein PduA compare
NOLOHH_12545 recA -0.7 -1.1 recombinase RecA compare
NOLOHH_20295 rluB -0.7 -2.6 23S rRNA pseudouridine(2605) synthase RluB compare
NOLOHH_18185 ydgI -0.7 -1.1 Putative arginine/ornithine antiporter compare


Specific Phenotypes

None in this experiment

For Escherichia coli ECOR27 in phage experiments

For phage Phage across organisms