Experiment set8IT096 for Pseudomonas putida KT2440

Compare to:

72hr timepoint from 1L M9/1% dextrose BATCH fermentation in 2L Sartorius Biostat reactor kept at 30% DO.

200 most important genes:

  gene name fitness t score description  
PP_4890 -5.7 -3.9 ATP phosphoribosyltransferase regulatory subunit compare
PP_0422 -5.2 -3.6 Indole-3-glycerol phosphate synthase compare
PP_3511 -5.1 -5.0 Branched-chain-amino-acid aminotransferase compare
PP_1110 -5.1 -3.5 serine acetyltransferase compare
PP_1109 -5.0 -14.3 Transcriptional regulator, GntR family compare
PP_1988 -5.0 -3.4 3-isopropylmalate dehydrogenase compare
PP_3376 -4.7 -3.2 putative phosphonate dehydrogenase compare
PP_4678 -4.7 -3.2 Ketol-acid reductoisomerase compare
PP_0787 -4.7 -3.2 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_2388 -4.6 -4.4 Transporter, LysE family compare
PP_3790 -4.5 -6.8 diaminopimelate epimerase compare
PP_0966 -4.4 -3.0 Histidinol dehydrogenase compare
PP_0290 -4.4 -3.0 Imidazole glycerol phosphate synthase subunit HisH compare
PP_2348 -4.3 -4.2 Sensor histidine kinase compare
PP_5076 -4.3 -10.1 L-glutamate synthase(NADPH) alpha subunit compare
PP_4680 -4.3 -7.2 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_2433 -4.2 -2.9 conserved protein of unknown function compare
PP_0420 -4.2 -7.5 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_1985 -4.2 -2.9 3-isopropylmalate dehydratase large subunit compare
PP_5104 -4.2 -5.7 thiazole synthase compare
PP_1079 -4.2 -2.9 Ornithine carbamoyltransferase compare
PP_5346 -4.1 -6.3 pyruvate carboxylase subunit B compare
PP_5145 -4.1 -29.1 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_0967 -4.0 -4.8 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_2390 -3.9 -7.0 Transcriptional regulator, LysR family compare
PP_5289 -3.8 -2.6 Acetylglutamate kinase compare
PP_0965 -3.8 -6.9 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_4922 -3.8 -8.8 Phosphomethylpyrimidine synthase compare
PP_5075 -3.7 -6.7 glutamate synthase (NADPH) beta subunit compare
PP_0293 -3.7 -2.5 Imidazole glycerol phosphate synthase subunit HisF compare
PP_1111 -3.7 -4.4 putative Synthetase compare
PP_2168 -3.6 -4.3 Transaldolase compare
PP_0417 -3.6 -10.4 Anthranilate synthase component 1 compare
PP_1233 -3.6 -2.5 sulfurtransferase compare
PP_5155 -3.5 -3.4 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_4679 -3.5 -2.4 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_1348 -3.4 -5.7 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase compare
PP_5097 -3.3 -9.8 homoserine O-acetyltransferase compare
PP_0289 -3.3 -3.9 Imidazoleglycerol-phosphate dehydratase compare
PP_2001 -3.3 -8.0 O-succinylhomoserine sulfhydrylase compare
PP_5098 -3.2 -6.1 methionine biosynthesis protein MetW compare
PP_1088 -3.1 -3.7 Argininosuccinate synthase compare
PP_1995 -3.1 -3.0 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_0421 -3.0 -7.1 Anthranilate phosphoribosyltransferase compare
PP_5128 -3.0 -8.3 Dihydroxy-acid dehydratase compare
PP_5185 -3.0 -2.1 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_5347 -3.0 -8.6 pyruvate carboxylase subunit A compare
PP_0735 -2.9 -2.0 molybdopterin-synthase adenylyltransferase compare
PP_1231 -2.9 -3.5 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_5348 -2.9 -9.3 Transcriptional regulator, LysR family compare
PP_4994 -2.9 -2.8 conserved protein of unknown function compare
PP_0362 -2.8 -11.9 Biotin synthase compare
PP_1986 -2.7 -1.9 3-isopropylmalate dehydratase small subunit compare
PP_3821 -2.7 -7.4 UTP-glucose-1-phosphate uridylyltransferase compare
PP_2327 -2.6 -5.2 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_0117 -2.6 -5.5 Zn(2+) ABC transporter - permease subunit compare
PP_0120 -2.5 -6.9 putative zinc ABC transporter compare
PP_4782 -2.5 -2.4 Phosphomethylpyrimidine kinase compare
PP_2371 -2.5 -3.3 Sulphite reductase hemoprotein, beta subunit compare
PP_1025 -2.5 -8.3 2-isopropylmalate synthase compare
PP_0292 -2.4 -3.3 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_4058 -2.4 -2.3 1,4-alpha-glucan branching enzyme compare
PP_1142 -2.3 -1.1 conserved protein of unknown function compare
PP_0630 -2.2 -1.6 DNA gyrase inhibitor YacG compare
PP_4480 -2.2 -6.5 arginine N-succinyltransferase, subunit alpha compare
PP_5267 -2.2 -2.1 putative cytochrome c5 compare
PP_0184 -2.2 -2.2 Argininosuccinate lyase compare
PP_5621 -2.2 -3.0 protein of unknown function compare
PP_4684 -2.1 -3.8 conserved protein of unknown function with kinase-like domain compare
PP_2328 -2.1 -2.0 Phosphoadenosine phosphosulfate reductase compare
PP_4909 -2.1 -2.0 phosphoserine phosphatase compare
PP_0948 -2.0 -3.7 Phosphocarrier protein HPr compare
PP_5303 -2.0 -3.1 aminoacrylate/iminopropionate hydrolase/deaminase compare
PP_5015 -2.0 -1.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_2341 -1.9 -1.8 6-carboxy-5,6,7,8-tetrahydropterin synthase compare
PP_0957 -1.9 -2.1 D-arabinose 5-phosphate isomerase compare
PP_3449 -1.9 -1.9 conserved exported protein of unknown function compare
PP_1898 -1.8 -1.3 MotA/TolQ/ExbB proton channel family protein compare
PP_4701 -1.8 -1.3 glucose-6-phosphate isomerase compare
PP_4262 -1.8 -1.2 Cytochrome oxidase maturation protein, cbb3-type compare
PP_2714 -1.8 -4.2 Sensor histidine kinase compare
PP_1011 -1.7 -6.9 glucokinase compare
PP_0083 -1.7 -1.2 tryptophan synthase beta chain compare
PP_0291 -1.7 -2.6 conserved protein of unknown function compare
PP_2370 -1.7 -2.3 conserved protein of unknown function compare
PP_5035 -1.7 -5.0 Histidine utilization repressor compare
PP_2217 -1.6 -3.2 enoyl-CoA hydratase compare
PP_4940 -1.6 -4.0 Putative glycosyltransferase compare
PP_5014 -1.6 -1.1 Phosphoribosyl-AMP cyclohydrolase compare
PP_1426 -1.6 -8.5 L-aspartate oxidase compare
PP_3999 -1.5 -1.5 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_5701 -1.5 -1.9 conserved protein of unknown function compare
PP_5327 -1.5 -4.7 putative phosphate ABC transporter, permease subunit compare
PP_5628 -1.5 -1.9 conserved protein of unknown function compare
PP_3505 -1.4 -2.2 conserved protein of unknown function compare
PP_0082 -1.4 -1.4 tryptophan synthase alpha chain compare
PP_1012 -1.4 -3.4 DNA-binding response regulator compare
PP_5329 -1.4 -2.6 putative phosphate ABC transporter, periplasmic phosphate-binding protein compare
PP_2044 -1.4 -1.7 conserved inner membrane protein of unknown function compare
PP_0118 -1.4 -4.2 zinc import ATP-binding protein compare
PP_0673 -1.4 -1.7 conserved protein of unknown function compare
PP_0951 -1.4 -5.0 Ribosome hibernation promoting factor compare
PP_5714 -1.3 -3.0 conserved protein of unknown function compare
PP_1309 -1.3 -5.4 conserved exported protein of unknown function compare
PP_1678 -1.3 -1.9 bifunctional cobinamide-P guanylyltransferase - adenosylcobinamide kinase compare
PP_4060 -1.3 -8.4 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase compare
PP_1018 -1.3 -4.0 mannose/glucose ABC transporter - ATP binding subunit compare
PP_5110 -1.3 -2.1 cytokinetic ring ABC transporter-like subunit - ATP-binding subunit compare
PP_5313 -1.3 -1.9 DNA-binding protein HU-alpha compare
PP_0022 -1.3 -0.9 hypothetical protein compare
PP_0261 -1.3 -3.5 adenosine-3'(2'),5'-bisphosphate nucleotidase compare
PP_2442 -1.2 -1.6 conserved protein of unknown function, DUF480 family compare
PP_4505 -1.2 -4.2 Sensor histidine kinase compare
PP_1355 -1.2 -10.7 Muropeptide permease AmpG compare
PP_1826 -1.2 -1.7 Hydrolase, isochorismatase family compare
PP_0119 -1.2 -2.3 putative zinc uptake regulation protein ZUR compare
PP_1328 -1.2 -1.5 Protein MraZ compare
PP_4977 -1.2 -5.3 5,10-methylenetetrahydrofolate reductase compare
PP_4785 -1.2 -4.4 conserved exported protein of unknown function compare
PP_3776 -1.2 -6.0 putative permease (RarD protein) compare
PP_1016 -1.2 -5.8 mannose/glucose ABC transporter, permease protein compare
PP_0834 -1.2 -0.8 Sec translocation complex subunit YajC compare
PP_3506 -1.1 -2.2 Magnesium chelatase, subunit ChII compare
PP_1015 -1.1 -5.0 mannose/glucose ABC transporter, glucose-binding periplasmic protein compare
PP_5328 -1.1 -2.6 putative phosphate transport system permease protein compare
PP_0377 -1.1 -1.5 coenzyme PQQ synthesis protein D compare
PP_4829 -1.1 -2.2 putative precorrin-3B synthase compare
PP_3453 -1.1 -5.8 putative Sensor protein RstB compare
PP_1589 -1.1 -3.3 uridylyltransferase compare
PP_1623 -1.1 -2.5 RNA polymerase, sigma S (sigma 38) factor compare
PP_1675 -1.1 -4.1 Subunit of adenosylcobinamide-phosphate synthase beta component compare
PP_2307 -1.1 -1.6 conserved protein of unknown function compare
PP_3443 -1.1 -5.0 putative glyceraldehyde-3-phosphate dehydrogenase compare
PP_2345 -1.1 -1.5 conserved exported protein of unknown function compare
PP_2403 -1.1 -1.4 Chemotaxis protein CheY compare
PP_1008 -1.0 -1.9 RNA polymerase subunit sigma-24 compare
PP_5393 -1.0 -0.5 putative metal-binding chaperone compare
PP_2145 -1.0 -5.5 beta-N-acetylglucosaminidase compare
PP_2747 -1.0 -1.8 conserved protein of unknown function compare
PP_2497 -1.0 -1.7 conserved protein of unknown function compare
PP_4266 -1.0 -2.5 Adenine phosphoribosyltransferase compare
PP_5047 -1.0 -4.0 two-component system sensory histidine kinase/phosphatase GlnL/GlnG compare
PP_1912 -1.0 -2.5 Phosphate acyltransferase compare
PP_0691 -1.0 -0.7 Glutamate 5-kinase compare
PP_3507 -1.0 -5.7 Aerobic cobaltochelatase subunit CobN compare
PP_1430 -1.0 -4.5 putative periplasmic serine endoprotease DegP-like compare
PP_2137 -1.0 -1.7 beta-ketoadipyl CoA thiolase, beta component compare
PP_4207 -1.0 -2.5 conserved protein of unknown function compare
PP_0507 -1.0 -3.9 putative ABC efflux transporter, ATP-binding protein compare
PP_2088 -1.0 -2.5 RNA polymerase sigma factor SigX compare
PP_0339 -1.0 -0.7 Pyruvate dehydrogenase E1 component compare
PP_0435 -1.0 -7.3 Peptidase, M23/M37 family compare
PP_2253 -1.0 -1.8 Transcriptional regulator, GntR family compare
PP_3519 -0.9 -0.6 putative Lipoprotein compare
PP_4379 -0.9 -3.2 Beta-ketoacyl-acyl-carrier-protein synthase I compare
PP_0406 -0.9 -3.6 Nucleotidyltransferase family protein compare
PP_4271 -0.9 -0.6 conserved protein of unknown function compare
PP_1303 -0.9 -3.3 Sulfate adenylyltransferase subunit 2 compare
PP_3102 -0.9 -1.9 conserved protein of unknown function compare
PP_0995 -0.9 -3.1 conserved membrane protein of unknown function compare
PP_t13 -0.9 -1.8 tRNA-Lys compare
PP_3786 -0.9 -5.8 aminotransferase compare
PP_0125 -0.9 -1.3 putative cytochrome c-type protein compare
PP_2326 -0.9 -5.1 Universal stress protein compare
PP_1304 -0.9 -4.6 sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase compare
PP_1716 -0.9 -1.8 Transcriptional regulator, Cro/CI family compare
PP_0127 -0.9 -2.4 Thiol:disulfide interchange protein compare
PP_4695 -0.9 -4.7 Sensory box histidine kinase compare
PP_4811 -0.9 -2.6 Gamma-glutamyl phosphate reductase compare
PP_4793 -0.9 -0.8 conserved protein of unknown function compare
PP_2429 -0.9 -1.3 putative Membrane protein compare
PP_5048 -0.9 -3.2 two-component system DNA-binding transcriptional dual regulator GlnL/GlnG compare
PP_4813 -0.9 -4.4 PAP2 family protein/DedA family protein compare
PP_1017 -0.9 -3.0 mannose/glucose ABC transporter, permease protein compare
PP_2181 -0.9 -2.6 Transcriptional regulator, Cro/CI family compare
PP_4837 -0.9 -1.8 conserved protein of unknown function compare
PP_2581 -0.9 -1.4 conserved protein of unknown function compare
PP_5203 -0.8 -3.4 5-formyltetrahydrofolate cyclo-ligase compare
PP_3508 -0.8 -2.0 Protein CobW compare
PP_2883 -0.8 -1.5 conserved protein of unknown function compare
PP_1679 -0.8 -1.6 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
PP_0508 -0.8 -1.9 conserved exported protein of unknown function compare
PP_5253 -0.8 -1.6 Arylesterase compare
PP_5471 -0.8 -1.5 putative response regulator receiver protein compare
PP_1664 -0.8 -0.8 phosphoribosylglycinamide formyltransferase 1 compare
PP_4632 -0.8 -3.0 dihydrofolate reductase / dihydromonapterin reductase compare
PP_0910 -0.8 -2.9 conserved exported protein of unknown function compare
PP_1778 -0.8 -1.8 Lipopolysaccharide ABC export system, permease protein compare
PP_4045 -0.8 -1.7 conserved protein of unknown function compare
PP_1013 -0.8 -3.0 Sensor histidine kinase compare
PP_2375 -0.8 -4.9 cobalamin-dependent methionine synthase compare
PP_2152 -0.8 -1.6 glycerophosphoryl diester phosphodiesterase compare
PP_4723 -0.8 -0.8 Carbamoyl-phosphate synthase large chain compare
PP_4642 -0.8 -0.7 Cyclic diguanosine monophosphate-binding protein compare
PP_1317 -0.8 -1.4 Ubiquinol-cytochrome c reductase iron-sulfur subunit compare
PP_3738 -0.8 -1.9 putative Transcriptional regulator VanR compare
PP_5486 -0.8 -1.5 conserved protein of unknown function compare
PP_3770 -0.8 -2.0 conserved protein of unknown function compare
PP_0881 -0.8 -2.4 dipeptide ABC transporter - putative membrane subunit compare
PP_0405 -0.8 -6.5 conserved protein of unknown function compare


Specific Phenotypes

For 3 genes in this experiment