Experiment set8IT092 for Pseudomonas putida KT2440

Compare to:

24hr timepoint from 1L M9/1% dextrose BATCH fermentation in 2L Sartorius Biostat reactor kept at 30% DO.

200 most important genes:

  gene name fitness t score description  
PP_4890 -5.3 -3.7 ATP phosphoribosyltransferase regulatory subunit compare
PP_3511 -4.9 -3.4 Branched-chain-amino-acid aminotransferase compare
PP_1109 -4.7 -12.5 Transcriptional regulator, GntR family compare
PP_3790 -4.5 -4.4 diaminopimelate epimerase compare
PP_1988 -4.3 -4.2 3-isopropylmalate dehydrogenase compare
PP_0787 -4.3 -2.9 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_0422 -4.2 -4.1 Indole-3-glycerol phosphate synthase compare
PP_4680 -4.2 -2.9 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_5076 -4.0 -8.2 L-glutamate synthase(NADPH) alpha subunit compare
PP_0966 -4.0 -2.8 Histidinol dehydrogenase compare
PP_4678 -4.0 -6.1 Ketol-acid reductoisomerase compare
PP_0967 -3.9 -2.7 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_5145 -3.8 -25.8 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_0290 -3.8 -3.7 Imidazole glycerol phosphate synthase subunit HisH compare
PP_2433 -3.8 -2.6 conserved protein of unknown function compare
PP_5104 -3.7 -5.7 thiazole synthase compare
PP_2390 -3.7 -5.7 Transcriptional regulator, LysR family compare
PP_1079 -3.7 -2.6 Ornithine carbamoyltransferase compare
PP_0420 -3.7 -6.7 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_4922 -3.7 -7.1 Phosphomethylpyrimidine synthase compare
PP_2388 -3.7 -4.4 Transporter, LysE family compare
PP_3376 -3.7 -4.3 putative phosphonate dehydrogenase compare
PP_0965 -3.6 -6.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_1111 -3.6 -3.5 putative Synthetase compare
PP_5075 -3.5 -4.8 glutamate synthase (NADPH) beta subunit compare
PP_5346 -3.5 -6.3 pyruvate carboxylase subunit B compare
PP_0417 -3.4 -7.9 Anthranilate synthase component 1 compare
PP_2348 -3.4 -4.0 Sensor histidine kinase compare
PP_0293 -3.3 -2.3 Imidazole glycerol phosphate synthase subunit HisF compare
PP_1110 -3.3 -3.2 serine acetyltransferase compare
PP_5347 -3.3 -6.7 pyruvate carboxylase subunit A compare
PP_2168 -3.2 -3.8 Transaldolase compare
PP_1348 -3.2 -4.4 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase compare
PP_5348 -3.2 -8.4 Transcriptional regulator, LysR family compare
PP_0421 -3.2 -5.3 Anthranilate phosphoribosyltransferase compare
PP_5097 -3.1 -8.8 homoserine O-acetyltransferase compare
PP_5289 -3.1 -3.1 Acetylglutamate kinase compare
PP_1233 -3.1 -2.2 sulfurtransferase compare
PP_4679 -3.1 -2.1 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_1995 -2.9 -2.0 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_5155 -2.9 -3.4 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_1088 -2.8 -2.8 Argininosuccinate synthase compare
PP_1985 -2.8 -2.8 3-isopropylmalate dehydratase large subunit compare
PP_5128 -2.8 -7.3 Dihydroxy-acid dehydratase compare
PP_0735 -2.7 -1.8 molybdopterin-synthase adenylyltransferase compare
PP_0292 -2.7 -2.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_4994 -2.7 -1.8 conserved protein of unknown function compare
PP_5185 -2.6 -1.8 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_1025 -2.6 -9.9 2-isopropylmalate synthase compare
PP_5098 -2.6 -5.3 methionine biosynthesis protein MetW compare
PP_2001 -2.5 -6.7 O-succinylhomoserine sulfhydrylase compare
PP_2370 -2.5 -1.7 conserved protein of unknown function compare
PP_0289 -2.5 -4.4 Imidazoleglycerol-phosphate dehydratase compare
PP_4782 -2.4 -1.6 Phosphomethylpyrimidine kinase compare
PP_5327 -2.3 -5.2 putative phosphate ABC transporter, permease subunit compare
PP_1986 -2.3 -1.6 3-isopropylmalate dehydratase small subunit compare
PP_2327 -2.3 -4.4 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_0362 -2.3 -9.9 Biotin synthase compare
PP_1231 -2.1 -2.5 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_2371 -2.1 -2.5 Sulphite reductase hemoprotein, beta subunit compare
PP_1142 -2.1 -1.1 conserved protein of unknown function compare
PP_1824 -2.0 -1.4 Smr domain protein compare
PP_0117 -2.0 -4.6 Zn(2+) ABC transporter - permease subunit compare
PP_4271 -2.0 -1.1 conserved protein of unknown function compare
PP_4058 -2.0 -1.4 1,4-alpha-glucan branching enzyme compare
PP_4480 -2.0 -5.1 arginine N-succinyltransferase, subunit alpha compare
PP_5328 -2.0 -3.0 putative phosphate transport system permease protein compare
PP_0120 -2.0 -5.5 putative zinc ABC transporter compare
PP_0184 -1.9 -1.3 Argininosuccinate lyase compare
PP_4561 -1.9 -1.0 stress response protein compare
PP_2718 -1.9 -2.2 arsenic resistance transcriptional regulator compare
PP_0291 -1.8 -2.2 conserved protein of unknown function compare
PP_1012 -1.8 -3.5 DNA-binding response regulator compare
PP_4909 -1.8 -1.3 phosphoserine phosphatase compare
PP_1011 -1.8 -6.2 glucokinase compare
PP_3505 -1.8 -2.1 conserved protein of unknown function compare
PP_2328 -1.8 -1.2 Phosphoadenosine phosphosulfate reductase compare
PP_0978 -1.8 -3.0 conserved protein of unknown function compare
PP_3693 -1.8 -3.3 putative Transcriptional regulator MvaT, P16 subunit compare
PP_2429 -1.7 -1.6 putative Membrane protein compare
PP_4897 -1.7 -3.6 N-acetylmuramoyl-L-alanine amidase compare
PP_0261 -1.7 -4.3 adenosine-3'(2'),5'-bisphosphate nucleotidase compare
PP_4505 -1.7 -4.3 Sensor histidine kinase compare
PP_5015 -1.6 -1.1 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_5303 -1.6 -2.5 aminoacrylate/iminopropionate hydrolase/deaminase compare
PP_1568 -1.6 -1.5 conserved protein of unknown function compare
PP_4684 -1.6 -3.1 conserved protein of unknown function with kinase-like domain compare
PP_2820 -1.6 -1.9 HTH-type transcriptional regulator nfxB compare
PP_0957 -1.6 -1.8 D-arabinose 5-phosphate isomerase compare
PP_4109 -1.5 -2.2 conserved protein of unknown function compare
PP_1864 -1.4 -1.6 conserved protein of unknown function compare
PP_1898 -1.4 -1.0 MotA/TolQ/ExbB proton channel family protein compare
PP_1309 -1.4 -6.6 conserved exported protein of unknown function compare
PP_5329 -1.4 -2.3 putative phosphate ABC transporter, periplasmic phosphate-binding protein compare
PP_0118 -1.4 -5.7 zinc import ATP-binding protein compare
PP_4829 -1.4 -2.1 putative precorrin-3B synthase compare
PP_5095 -1.3 -0.9 pyrroline-5-carboxylate reductase compare
PP_0948 -1.3 -3.0 Phosphocarrier protein HPr compare
PP_1979 -1.3 -1.3 putative Hydrolase compare
PP_5167 -1.3 -2.3 conserved hypothetical protein compare
PP_3098 -1.3 -1.7 conserved protein of unknown function compare
PP_4977 -1.3 -5.4 5,10-methylenetetrahydrofolate reductase compare
PP_0083 -1.3 -1.2 tryptophan synthase beta chain compare
PP_2497 -1.3 -1.5 conserved protein of unknown function compare
PP_1729 -1.3 -1.9 conserved protein of unknown function compare
PP_2928 -1.3 -4.6 Saccharopine dehydrogenase compare
PP_5014 -1.3 -0.9 Phosphoribosyl-AMP cyclohydrolase compare
PP_3105 -1.2 -1.0 conserved membrane protein of unknown function compare
PP_0627 -1.2 -1.7 conserved protein of unknown function compare
PP_1528 -1.2 -1.1 conserved protein of unknown function compare
PP_1355 -1.2 -10.2 Muropeptide permease AmpG compare
PP_2088 -1.2 -2.4 RNA polymerase sigma factor SigX compare
PP_2181 -1.2 -2.8 Transcriptional regulator, Cro/CI family compare
PP_1999 -1.2 -1.6 membrane protein required for colicin V production compare
PP_1016 -1.2 -5.1 mannose/glucose ABC transporter, permease protein compare
PP_3999 -1.2 -0.8 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_0082 -1.2 -0.8 tryptophan synthase alpha chain compare
PP_4060 -1.2 -7.3 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase compare
PP_4642 -1.2 -0.9 Cyclic diguanosine monophosphate-binding protein compare
PP_4226 -1.2 -2.4 conserved protein of unknown function compare
PP_1731 -1.2 -2.2 23S rRNA (746) and tRNA (32) pseudouridine synthase compare
PP_4792 -1.2 -1.7 conserved exported protein of unknown function compare
PP_2714 -1.2 -2.7 Sensor histidine kinase compare
PP_5652 -1.2 -1.1 conserved protein of unknown function, phage origin compare
PP_2159 -1.1 -3.1 Copper-binding protein, plastocyanin/azurin family compare
PP_3833 -1.1 -2.7 Response regulator compare
PP_4836 -1.1 -1.7 conserved exported protein of unknown function compare
PP_1328 -1.1 -1.3 Protein MraZ compare
PP_1912 -1.1 -2.3 Phosphate acyltransferase compare
PP_5051 -1.1 -1.5 conserved protein of unknown function compare
PP_3417 -1.1 -2.9 D-gluconate transporter compare
PP_2060 -1.1 -1.5 DNA-binding transcriptional dual regulator - SoxR-reversible one-electron oxidation of its [2Fe-2S] cluster, NADPH-dependent compare
PP_5203 -1.1 -3.8 5-formyltetrahydrofolate cyclo-ligase compare
PP_3726 -1.1 -1.1 Enoyl-CoA hydratase/isomerase family protein compare
PP_3506 -1.1 -2.1 Magnesium chelatase, subunit ChII compare
PP_2186 -1.1 -2.6 putative Formate dehydrogenase, delta subunit compare
PP_1426 -1.1 -5.8 L-aspartate oxidase compare
PP_0980 -1.1 -2.9 Probable cytosol aminopeptidase compare
PP_3850 -1.1 -2.4 conserved protein of unknown function compare
PP_1015 -1.1 -4.3 mannose/glucose ABC transporter, glucose-binding periplasmic protein compare
PP_1097 -1.1 -1.0 Methionine--tRNA ligase compare
PP_2929 -1.1 -3.4 Carboxynorspermidine/carboxyspermidine decarboxylase compare
PP_5674 -1.1 -2.0 conserved protein of unknown function compare
PP_2145 -1.1 -5.1 beta-N-acetylglucosaminidase compare
PP_0880 -1.1 -2.1 dipeptide ABC transporter - putative membrane subunit compare
PP_0821 -1.0 -2.7 conserved exported protein of unknown function compare
PP_2883 -1.0 -1.6 conserved protein of unknown function compare
PP_1009 -1.0 -2.4 glyceraldehyde-3-phosphate dehydrogenase compare
PP_2203 -1.0 -1.2 conserved protein of unknown function compare
PP_4695 -1.0 -4.4 Sensory box histidine kinase compare
PP_0905 -1.0 -1.5 conserved exported protein of unknown function compare
PP_5448 -1.0 -2.1 conserved protein of unknown function compare
PP_0951 -1.0 -3.4 Ribosome hibernation promoting factor compare
PP_5628 -1.0 -1.5 conserved protein of unknown function compare
PP_4320 -1.0 -2.5 cytochrome c-type biogenesis protein compare
PP_0683 -1.0 -2.1 conserved protein of unknown function compare
PP_0022 -1.0 -0.7 hypothetical protein compare
PP_1623 -1.0 -1.9 RNA polymerase, sigma S (sigma 38) factor compare
PP_4223 -1.0 -0.9 diaminobutyrate-2-oxoglutarate transaminase compare
PP_2217 -1.0 -2.0 enoyl-CoA hydratase compare
PP_5552 -0.9 -1.6 conserved protein of unknown function compare
PP_3787 -0.9 -3.7 conserved protein of unknown function compare
PP_2722 -0.9 -2.9 conserved protein of unknown function compare
PP_1779 -0.9 -2.3 Lipopolysaccharide ABC export system, ATP-binding protein compare
PP_1326 -0.9 -1.5 16S rRNA 2'-O-ribose C1402 methyltransferase compare
PP_0345 -0.9 -1.8 putative Heptose kinase WapP compare
PP_3401 -0.9 -2.7 conserved protein of unknown function compare
PP_1062 -0.9 -1.9 MutT/nudix family protein compare
PP_2499 -0.9 -0.9 conserved protein of unknown function compare
PP_3407 -0.9 -1.8 conserved protein of unknown function compare
PP_1349 -0.9 -2.7 ATP:cob(I)alamin adenosyltransferase compare
PP_4827 -0.9 -3.6 Precorrin-2 C(20)-methyltransferase compare
PP_3037 -0.9 -1.8 C4-type zinc finger protein, DksA/TraR family compare
PP_4251 -0.9 -1.3 cytochrome c oxidase subunit, cbb3-type compare
PP_3411 -0.9 -0.8 conserved protein of unknown function compare
PP_1473 -0.9 -1.6 conserved protein of unknown function compare
PP_4263 -0.9 -1.0 putative membrane-bounded cytochrome biogenesis cycZ-like domain, copper tolerance protein compare
PP_0995 -0.9 -2.7 conserved membrane protein of unknown function compare
PP_0435 -0.9 -6.2 Peptidase, M23/M37 family compare
PP_2326 -0.9 -4.2 Universal stress protein compare
PP_3443 -0.9 -3.8 putative glyceraldehyde-3-phosphate dehydrogenase compare
PP_1013 -0.9 -2.7 Sensor histidine kinase compare
PP_0628 -0.9 -2.3 conserved protein of unknown function compare
PP_2307 -0.9 -1.3 conserved protein of unknown function compare
PP_4785 -0.9 -3.6 conserved exported protein of unknown function compare
PP_2299 -0.9 -1.2 Trigger factor compare
PP_2716 -0.9 -2.2 arsenate reductase compare
PP_0125 -0.9 -1.4 putative cytochrome c-type protein compare
PP_0910 -0.9 -2.6 conserved exported protein of unknown function compare
PP_0313 -0.9 -1.9 putative electron transfer flavoprotein beta subunit compare
PP_4793 -0.9 -1.8 conserved protein of unknown function compare
PP_1304 -0.8 -3.9 sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase compare
PP_3247 -0.8 -2.4 Transporter, bile acid/Na+ symporter family compare
PP_1679 -0.8 -1.5 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
PP_1778 -0.8 -1.5 Lipopolysaccharide ABC export system, permease protein compare
PP_4199 -0.8 -0.8 putative Lipoprotein compare
PP_5048 -0.8 -2.5 two-component system DNA-binding transcriptional dual regulator GlnL/GlnG compare
PP_5035 -0.8 -2.7 Histidine utilization repressor compare
PP_2857 -0.8 -1.4 conserved exported protein of unknown function compare
PP_1635 -0.8 -1.7 DNA-binding response regulator compare


Specific Phenotypes

For 2 genes in this experiment