Experiment set8IT064 for Pseudomonas putida KT2440

Compare to:

72hr timepoint from 1L M9/1% dextrose BATCH fermentation in 2L Sartorius Biostat reactor kept at 10% DO.

200 most important genes:

  gene name fitness t score description  
PP_4890 -4.8 -3.3 ATP phosphoribosyltransferase regulatory subunit compare
PP_3511 -4.6 -4.5 Branched-chain-amino-acid aminotransferase compare
PP_0787 -4.6 -3.2 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_0290 -4.5 -3.1 Imidazole glycerol phosphate synthase subunit HisH compare
PP_1988 -4.2 -5.0 3-isopropylmalate dehydrogenase compare
PP_0293 -4.1 -2.8 Imidazole glycerol phosphate synthase subunit HisF compare
PP_0967 -4.0 -2.8 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_0966 -4.0 -3.9 Histidinol dehydrogenase compare
PP_4678 -3.9 -7.0 Ketol-acid reductoisomerase compare
PP_4723 -3.9 -2.7 Carbamoyl-phosphate synthase large chain compare
PP_0292 -3.8 -2.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_1985 -3.8 -2.6 3-isopropylmalate dehydratase large subunit compare
PP_0417 -3.7 -5.7 Anthranilate synthase component 1 compare
PP_1079 -3.7 -2.5 Ornithine carbamoyltransferase compare
PP_4680 -3.6 -5.6 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_5104 -3.6 -5.0 thiazole synthase compare
PP_0422 -3.6 -3.5 Indole-3-glycerol phosphate synthase compare
PP_4724 -3.6 -2.5 Carbamoyl-phosphate synthase small chain compare
PP_0965 -3.6 -6.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_2348 -3.5 -4.2 Sensor histidine kinase compare
PP_2168 -3.5 -2.4 Transaldolase compare
PP_0261 -3.4 -3.3 adenosine-3'(2'),5'-bisphosphate nucleotidase compare
PP_4217 -3.4 -15.7 outer membrane ferripyoverdine receptor FpvA, TonB-dependent compare
PP_4994 -3.3 -3.3 conserved protein of unknown function compare
PP_5128 -3.3 -7.1 Dihydroxy-acid dehydratase compare
PP_5097 -3.3 -8.1 homoserine O-acetyltransferase compare
PP_5155 -3.3 -3.2 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_1111 -3.3 -3.9 putative Synthetase compare
PP_1233 -3.2 -2.2 sulfurtransferase compare
PP_5295 -3.1 -2.2 conserved protein of unknown function compare
PP_4505 -3.1 -4.3 Sensor histidine kinase compare
PP_1995 -3.1 -2.2 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_3892 -3.1 -1.7 conserved protein of unknown function compare
PP_0421 -3.1 -4.7 Anthranilate phosphoribosyltransferase compare
PP_4208 -3.1 -5.1 RNA polymerase sigma-70 factor, ECF subfamily compare
PP_4701 -3.1 -1.6 glucose-6-phosphate isomerase compare
PP_0735 -3.0 -2.1 molybdopterin-synthase adenylyltransferase compare
PP_1088 -3.0 -2.1 Argininosuccinate synthase compare
PP_1082 -3.0 -4.1 bacterioferritin compare
PP_1231 -3.0 -2.0 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_1898 -2.9 -2.0 MotA/TolQ/ExbB proton channel family protein compare
PP_4909 -2.8 -2.0 phosphoserine phosphatase compare
PP_2433 -2.8 -2.5 conserved protein of unknown function compare
PP_0289 -2.8 -4.2 Imidazoleglycerol-phosphate dehydratase compare
PP_5185 -2.7 -1.9 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_5289 -2.7 -2.6 Acetylglutamate kinase compare
PP_5098 -2.7 -4.5 methionine biosynthesis protein MetW compare
PP_4058 -2.7 -1.8 1,4-alpha-glucan branching enzyme compare
PP_0691 -2.6 -1.8 Glutamate 5-kinase compare
PP_3241 -2.6 -1.4 conserved exported protein of unknown function compare
PP_2001 -2.5 -6.3 O-succinylhomoserine sulfhydrylase compare
PP_1986 -2.5 -1.7 3-isopropylmalate dehydratase small subunit compare
PP_2327 -2.4 -3.7 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_4199 -2.4 -1.3 putative Lipoprotein compare
PP_0420 -2.4 -7.2 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_4060 -2.4 -9.5 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase compare
PP_5267 -2.4 -2.3 putative cytochrome c5 compare
PP_4782 -2.4 -1.6 Phosphomethylpyrimidine kinase compare
PP_1779 -2.4 -1.6 Lipopolysaccharide ABC export system, ATP-binding protein compare
PP_1008 -2.3 -2.1 RNA polymerase subunit sigma-24 compare
PP_1109 -2.3 -8.8 Transcriptional regulator, GntR family compare
PP_0508 -2.3 -2.7 conserved exported protein of unknown function compare
PP_0362 -2.3 -8.7 Biotin synthase compare
PP_3880 -2.2 -1.6 conserved exported protein of unknown function compare
PP_0913 -2.1 -3.8 conserved exported protein of unknown function compare
PP_0963 -2.1 -2.4 putative BolA family protein compare
PP_0291 -2.0 -2.4 conserved protein of unknown function compare
PP_5346 -2.0 -6.5 pyruvate carboxylase subunit B compare
PP_0908 -2.0 -3.5 conserved exported protein of unknown function compare
PP_1110 -1.9 -2.0 serine acetyltransferase compare
PP_4828 -1.9 -1.3 Precorrin-8X methylmutase compare
PP_1142 -1.9 -1.0 conserved protein of unknown function compare
PP_2253 -1.9 -1.6 Transcriptional regulator, GntR family compare
PP_1025 -1.9 -6.3 2-isopropylmalate synthase compare
PP_0801 -1.9 -1.8 conserved exported protein of unknown function compare
PP_5583 -1.9 -1.7 conserved protein of unknown function compare
PP_0184 -1.9 -1.3 Argininosuccinate lyase compare
PP_0127 -1.8 -2.8 Thiol:disulfide interchange protein compare
PP_4679 -1.8 -2.8 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_1198 -1.8 -1.2 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_5014 -1.8 -1.2 Phosphoribosyl-AMP cyclohydrolase compare
PP_5015 -1.8 -1.7 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_1348 -1.7 -3.9 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase compare
PP_4008 -1.7 -1.2 ATP-dependent serine protease compare
PP_1083 -1.7 -4.0 (2Fe-2S)-binding protein compare
PP_4836 -1.7 -2.0 conserved exported protein of unknown function compare
PP_5232 -1.7 -2.0 conserved protein of unknown function compare
PP_5347 -1.7 -6.8 pyruvate carboxylase subunit A compare
PP_5348 -1.7 -6.2 Transcriptional regulator, LysR family compare
PP_5303 -1.7 -2.5 aminoacrylate/iminopropionate hydrolase/deaminase compare
PP_1787 -1.6 -2.8 conserved protein of unknown function compare
PP_4922 -1.6 -5.9 Phosphomethylpyrimidine synthase compare
PP_2370 -1.6 -1.9 conserved protein of unknown function compare
PP_2714 -1.6 -4.1 Sensor histidine kinase compare
PP_2880 -1.6 -2.2 Transcriptional regulator, TetR family compare
PP_0910 -1.6 -2.6 conserved exported protein of unknown function compare
PP_3798 -1.6 -3.6 conserved protein of unknown function compare
PP_0274 -1.6 -1.8 putative transcriptional regulator containing HTH domain compare
PP_3799 -1.5 -2.3 conserved exported protein of unknown function compare
PP_1034 -1.5 -5.0 multicopper oxidase compare
PP_0509 -1.5 -2.0 conserved protein of unknown function compare
PP_2073 -1.5 -2.3 Acetyltransferase, GNAT family compare
PP_4942 -1.5 -1.4 conserved protein of unknown function compare
PP_4262 -1.5 -1.8 Cytochrome oxidase maturation protein, cbb3-type compare
PP_4504 -1.5 -1.7 conserved exported protein of unknown function compare
PP_4471 -1.5 -1.7 Magnesium transporter compare
PP_5702 -1.5 -2.4 conserved protein of unknown function compare
PP_2326 -1.4 -5.5 Universal stress protein compare
PP_3614 -1.4 -1.7 conserved membrane protein of unknown function compare
PP_1261 -1.4 -2.6 2-ketoaldonate reductase / hydroxypyruvate/glyoxylate reductase compare
PP_4685 -1.4 -4.1 conserved protein of unknown function compare
PP_0839 -1.4 -1.9 tRNA Cm32/Um32 methyltransferase compare
PP_3409 -1.4 -1.7 putative Cobalamin biosynthesis protein cobE compare
PP_4923 -1.4 -5.7 Outer membrane efflux protein compare
PP_3376 -1.4 -3.4 putative phosphonate dehydrogenase compare
PP_0111 -1.4 -2.9 Electron transport protein SCO1/SenC compare
PP_5748 -1.4 -1.8 cytochrome c heme lyase subunit compare
PP_3098 -1.3 -1.2 conserved protein of unknown function compare
PP_4687 -1.3 -2.3 Hemin import ATP-binding protein HmuV compare
PP_5328 -1.3 -2.6 putative phosphate transport system permease protein compare
PP_2196 -1.3 -2.0 agmatinase compare
PP_3662 -1.3 -4.3 conserved protein of unknown function compare
PP_4070 -1.3 -3.7 conserved protein of unknown function compare
PP_5507 -1.3 -2.0 protein of unknown function compare
PP_0995 -1.3 -3.3 conserved membrane protein of unknown function compare
PP_0909 -1.3 -3.6 conserved exported protein of unknown function compare
PP_3365 -1.3 -1.2 Acetolactate synthase compare
PP_3765 -1.3 -2.3 H-NS family protein MvaT compare
PP_3447 -1.2 -1.1 conserved membrane protein of unknown function compare
PP_2631 -1.2 -1.3 putative cellulose biosynthesis, BcsF/YhjT compare
PP_3453 -1.2 -5.2 putative Sensor protein RstB compare
PP_5052 -1.2 -2.0 tRNA(Leu) mC34,mU34 2'-O-ribose methyltransferase, AdoMet-dependent compare
PP_5717 -1.2 -1.5 conserved protein of unknown function compare
PP_5659 -1.2 -1.8 protein of unknown function compare
PP_5610 -1.2 -1.7 protein of unknown function compare
PP_4247 -1.2 -1.2 Exonuclease compare
PP_1632 -1.2 -1.1 conserved protein of unknown function compare
PP_3333 -1.2 -2.6 conserved protein of unknown function compare
PP_4997 -1.2 -1.7 pyrimidine operon regulatory protein/uracil phosphoribosyltransferase compare
PP_3935 -1.2 -1.7 conserved protein of unknown function compare
PP_0972 -1.2 -2.2 UPF0213 protein PP_0972 compare
PP_3539 -1.2 -1.4 putative Transcriptional regulator compare
PP_3971 -1.2 -1.4 conserved protein of unknown function compare
PP_5331 -1.2 -3.3 Long-chain acyl-CoA thioester hydrolase compare
PP_2371 -1.2 -2.6 Sulphite reductase hemoprotein, beta subunit compare
PP_4785 -1.1 -4.0 conserved exported protein of unknown function compare
PP_2309 -1.1 -1.3 conserved protein of unknown function compare
PP_4136 -1.1 -1.3 Transcriptional regulator, LuxR family compare
PP_0083 -1.1 -0.8 tryptophan synthase beta chain compare
PP_3258 -1.1 -1.9 conserved protein of unknown function compare
PP_2903 -1.1 -1.4 peptidyl-prolyl cis-trans isomerase B (rotamase B) compare
PP_5589 -1.1 -1.8 protein of unknown function containing Rhs repeat-associated core domain compare
PP_5471 -1.1 -1.7 putative response regulator receiver protein compare
PP_0435 -1.1 -7.7 Peptidase, M23/M37 family compare
PP_4009 -1.1 -2.9 ATP-dependent Clp protease adapter protein ClpS compare
PP_4073 -1.1 -1.5 conserved exported protein of unknown function compare
PP_1778 -1.1 -1.0 Lipopolysaccharide ABC export system, permease protein compare
PP_2826 -1.1 -1.9 Transcriptional regulator MexT compare
PP_5329 -1.1 -2.4 putative phosphate ABC transporter, periplasmic phosphate-binding protein compare
PP_0585 -1.1 -1.8 putative metal-sensitive transcriptional regulator, MerR family compare
PP_5095 -1.0 -1.2 pyrroline-5-carboxylate reductase compare
PP_0048 -1.0 -1.1 conserved protein of unknown function compare
PP_0978 -1.0 -2.5 conserved protein of unknown function compare
PP_2328 -1.0 -2.3 Phosphoadenosine phosphosulfate reductase compare
PP_0663 -1.0 -1.8 Transcriptional regulator, AsnC family compare
PP_0695 -1.0 -3.0 conserved protein of unknown function compare
PP_2907 -1.0 -1.5 DNA-binding response regulator compare
PP_4296 -1.0 -1.4 conserved exported protein of unknown function compare
PP_0082 -1.0 -1.0 tryptophan synthase alpha chain compare
PP_4385 -1.0 -3.3 flagellar basal-body rod protein FlgG compare
PP_0401 -1.0 -1.2 Ribosomal RNA small subunit methyltransferase A compare
PP_4150 -1.0 -2.6 microcin C transporter - ATP binding subunit compare
PP_4593 -1.0 -1.0 conserved protein of unknown function compare
PP_1776 -1.0 -7.5 Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase compare
PP_0809 -1.0 -3.8 disulfide bond formation protein B compare
PP_2675 -1.0 -1.9 Cytochrome c-type protein compare
PP_4236 -1.0 -2.7 putative Thiol:disulfide interchange protein dsbE compare
PP_4342 -1.0 -0.7 flagellar synthesis regulator, putative ATPase compare
PP_2643 -1.0 -3.1 aromatic acid chemoreceptor compare
PP_0409 -1.0 -4.7 Sensory box histidine kinase compare
PP_2345 -0.9 -1.6 conserved exported protein of unknown function compare
PP_1041 -0.9 -1.1 twin arginine protein export complex subunit compare
PP_2322 -0.9 -3.6 Major outer membrane lipoprotein compare
PP_4738 -0.9 -1.8 conserved exported protein of unknown function compare
PP_2681 -0.9 -0.9 coenzyme PQQ synthesis protein D compare
PP_5365 -0.9 -4.9 putative fatty acid methyltransferase compare
PP_5508 -0.9 -0.8 conserved protein of unknown function compare
PP_2497 -0.9 -1.1 conserved protein of unknown function compare
PP_4847 -0.9 -1.6 chaperone modulatory of CbpA co-chaperone protein compare
PP_5499 -0.9 -1.7 conserved protein of unknown function compare
PP_1683 -0.9 -1.6 Transcriptional regulator, MarR family compare
PP_2388 -0.9 -2.1 Transporter, LysE family compare
PP_5083 -0.9 -1.9 putative Type IV pili biogenesis protein PilM compare
PP_4286 -0.9 -3.2 allantoinase compare
PP_5327 -0.9 -2.4 putative phosphate ABC transporter, permease subunit compare
PP_1178 -0.9 -1.8 conserved protein of unknown function compare
PP_5191 -0.9 -1.6 conserved exported protein of unknown function compare
PP_0700 -0.9 -3.8 putative Transmembrane sensor compare
PP_0425 -0.9 -1.6 conserved protein of unknown function compare
PP_4689 -0.9 -2.1 Heme/hemin ABC transporter, periplasmic heme/hemin-binding protein compare


Specific Phenotypes

For 6 genes in this experiment