Experiment set8IT062 for Pseudomonas putida KT2440

Compare to:

48hr timepoint from 1L M9/1% dextrose BATCH fermentation in 2L Sartorius Biostat reactor kept at 10% DO.

200 most important genes:

  gene name fitness t score description  
PP_4890 -5.0 -3.5 ATP phosphoribosyltransferase regulatory subunit compare
PP_3511 -5.0 -4.8 Branched-chain-amino-acid aminotransferase compare
PP_2433 -4.9 -3.4 conserved protein of unknown function compare
PP_0787 -4.8 -3.3 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_0290 -4.8 -3.3 Imidazole glycerol phosphate synthase subunit HisH compare
PP_2348 -4.6 -3.2 Sensor histidine kinase compare
PP_1988 -4.6 -4.5 3-isopropylmalate dehydrogenase compare
PP_0966 -4.4 -3.0 Histidinol dehydrogenase compare
PP_4678 -4.4 -6.0 Ketol-acid reductoisomerase compare
PP_0293 -4.3 -3.0 Imidazole glycerol phosphate synthase subunit HisF compare
PP_4723 -4.1 -2.9 Carbamoyl-phosphate synthase large chain compare
PP_1985 -4.1 -2.8 3-isopropylmalate dehydratase large subunit compare
PP_0967 -4.0 -5.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_0965 -3.9 -6.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_4680 -3.9 -5.4 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_1079 -3.9 -2.7 Ornithine carbamoyltransferase compare
PP_4724 -3.9 -2.7 Carbamoyl-phosphate synthase small chain compare
PP_0422 -3.8 -3.7 Indole-3-glycerol phosphate synthase compare
PP_4994 -3.8 -2.6 conserved protein of unknown function compare
PP_1110 -3.8 -4.5 serine acetyltransferase compare
PP_0261 -3.7 -3.6 adenosine-3'(2'),5'-bisphosphate nucleotidase compare
PP_5104 -3.7 -5.7 thiazole synthase compare
PP_4217 -3.7 -17.1 outer membrane ferripyoverdine receptor FpvA, TonB-dependent compare
PP_0417 -3.6 -9.3 Anthranilate synthase component 1 compare
PP_5155 -3.6 -3.5 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_2168 -3.6 -4.2 Transaldolase compare
PP_5097 -3.5 -8.6 homoserine O-acetyltransferase compare
PP_0292 -3.5 -3.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_5289 -3.5 -2.4 Acetylglutamate kinase compare
PP_4679 -3.3 -2.3 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_1088 -3.2 -2.2 Argininosuccinate synthase compare
PP_1231 -3.2 -2.2 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_0735 -3.2 -2.2 molybdopterin-synthase adenylyltransferase compare
PP_1233 -3.1 -3.0 sulfurtransferase compare
PP_1898 -3.1 -2.1 MotA/TolQ/ExbB proton channel family protein compare
PP_1111 -3.1 -4.7 putative Synthetase compare
PP_1995 -3.0 -3.0 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_5185 -3.0 -2.1 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_4058 -3.0 -2.0 1,4-alpha-glucan branching enzyme compare
PP_5098 -2.9 -4.9 methionine biosynthesis protein MetW compare
PP_5128 -2.9 -7.9 Dihydroxy-acid dehydratase compare
PP_0421 -2.9 -6.2 Anthranilate phosphoribosyltransferase compare
PP_0691 -2.9 -2.0 Glutamate 5-kinase compare
PP_0420 -2.8 -8.0 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_1986 -2.7 -1.9 3-isopropylmalate dehydratase small subunit compare
PP_4909 -2.7 -3.2 phosphoserine phosphatase compare
PP_0289 -2.7 -5.2 Imidazoleglycerol-phosphate dehydratase compare
PP_1774 -2.7 -2.6 conserved exported protein of unknown function compare
PP_1109 -2.6 -7.9 Transcriptional regulator, GntR family compare
PP_4505 -2.5 -4.9 Sensor histidine kinase compare
PP_5015 -2.5 -1.7 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_0362 -2.4 -9.7 Biotin synthase compare
PP_2001 -2.4 -7.0 O-succinylhomoserine sulfhydrylase compare
PP_4782 -2.4 -2.8 Phosphomethylpyrimidine kinase compare
PP_0593 -2.3 -1.2 putative ribosome-binding factor compare
PP_2327 -2.3 -4.7 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_3505 -2.2 -1.9 conserved protein of unknown function compare
PP_4208 -2.2 -5.5 RNA polymerase sigma-70 factor, ECF subfamily compare
PP_4009 -2.2 -4.6 ATP-dependent Clp protease adapter protein ClpS compare
PP_0184 -2.2 -1.5 Argininosuccinate lyase compare
PP_4060 -2.1 -10.2 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase compare
PP_0508 -2.1 -2.6 conserved exported protein of unknown function compare
PP_5346 -2.1 -5.8 pyruvate carboxylase subunit B compare
PP_5347 -2.1 -7.7 pyruvate carboxylase subunit A compare
PP_3519 -2.0 -1.1 putative Lipoprotein compare
PP_1034 -2.0 -5.9 multicopper oxidase compare
PP_2371 -2.0 -3.9 Sulphite reductase hemoprotein, beta subunit compare
PP_5014 -2.0 -1.4 Phosphoribosyl-AMP cyclohydrolase compare
PP_0910 -2.0 -3.8 conserved exported protein of unknown function compare
PP_1198 -2.0 -1.4 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_1779 -2.0 -2.7 Lipopolysaccharide ABC export system, ATP-binding protein compare
PP_4213 -2.0 -1.9 putative dipeptidase compare
PP_1568 -1.9 -1.4 conserved protein of unknown function compare
PP_1025 -1.9 -6.9 2-isopropylmalate synthase compare
PP_5580 -1.9 -2.3 protein of unknown function compare
PP_5007 -1.9 -1.3 Polyhydroxyalkanoate granule-associated protein GA2 compare
PP_1176 -1.9 -1.3 conserved protein of unknown function compare
PP_0022 -1.9 -1.0 hypothetical protein compare
PP_0345 -1.8 -3.5 putative Heptose kinase WapP compare
PP_3840 -1.7 -1.6 conserved protein of unknown function compare
PP_4008 -1.7 -2.4 ATP-dependent serine protease compare
PP_0127 -1.7 -3.2 Thiol:disulfide interchange protein compare
PP_1224 -1.7 -3.2 periplasmic subunit of the TolQRA transport system compare
PP_0846 -1.7 -1.1 DnaK-like molecular chaperone specific for IscU compare
PP_4937 -1.7 -1.1 toluene tolerance protein compare
PP_3797 -1.7 -4.6 conserved membrane protein of unknown function compare
PP_0913 -1.6 -3.8 conserved exported protein of unknown function compare
PP_4836 -1.6 -2.4 conserved exported protein of unknown function compare
PP_0841 -1.6 -3.5 DNA-binding transcriptional dual regulator 2Fe-2S cluster IscR compare
PP_3539 -1.6 -2.4 putative Transcriptional regulator compare
PP_5348 -1.6 -5.6 Transcriptional regulator, LysR family compare
PP_1083 -1.6 -2.5 (2Fe-2S)-binding protein compare
PP_2328 -1.6 -3.1 Phosphoadenosine phosphosulfate reductase compare
PP_4922 -1.5 -6.8 Phosphomethylpyrimidine synthase compare
PP_4471 -1.5 -2.1 Magnesium transporter compare
PP_3999 -1.5 -2.6 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_4070 -1.5 -3.3 conserved protein of unknown function compare
PP_3105 -1.5 -1.4 conserved membrane protein of unknown function compare
PP_0291 -1.4 -1.9 conserved protein of unknown function compare
PP_0083 -1.4 -1.0 tryptophan synthase beta chain compare
PP_0082 -1.4 -1.0 tryptophan synthase alpha chain compare
PP_4247 -1.4 -1.4 Exonuclease compare
PP_1778 -1.4 -0.9 Lipopolysaccharide ABC export system, permease protein compare
PP_1348 -1.4 -3.9 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase compare
PP_t12 -1.3 -0.7 tRNA-Thr compare
PP_0909 -1.3 -3.9 conserved exported protein of unknown function compare
PP_t29 -1.3 -0.9 tRNA-Ala compare
PP_0379 -1.3 -3.9 Coenzyme PQQ synthesis protein B compare
PP_5162 -1.3 -2.5 conserved exported protein of unknown function compare
PP_3924 -1.3 -2.1 conserved protein of unknown function compare
PP_5110 -1.3 -1.9 cytokinetic ring ABC transporter-like subunit - ATP-binding subunit compare
PP_1466 -1.3 -2.4 Long-chain acyl-CoA thioester hydrolase family protein compare
PP_4829 -1.3 -2.1 putative precorrin-3B synthase compare
PP_0801 -1.3 -1.5 conserved exported protein of unknown function compare
PP_0048 -1.2 -1.3 conserved protein of unknown function compare
PP_2379 -1.2 -3.4 putative cytochrome oxidase biogenesis protein compare
PP_3880 -1.2 -1.3 conserved exported protein of unknown function compare
PP_3833 -1.2 -2.1 Response regulator compare
PP_4662 -1.2 -2.3 conserved protein of unknown function compare
PP_4342 -1.2 -0.9 flagellar synthesis regulator, putative ATPase compare
PP_4923 -1.2 -5.7 Outer membrane efflux protein compare
PP_4785 -1.2 -3.1 conserved exported protein of unknown function compare
PP_0852 -1.2 -0.8 Transcriptional regulator, Cro/CI family compare
PP_2804 -1.2 -2.4 Hydrolase, alpha/beta fold family compare
PP_4591 -1.2 -2.5 Ribonuclease D compare
PP_1082 -1.2 -2.4 bacterioferritin compare
PP_1828 -1.2 -2.7 conserved protein of unknown function compare
PP_5604 -1.2 -2.2 putative subtilisin-like serine protease compare
PP_0908 -1.2 -3.3 conserved exported protein of unknown function compare
PP_4263 -1.1 -2.1 putative membrane-bounded cytochrome biogenesis cycZ-like domain, copper tolerance protein compare
PP_4593 -1.1 -1.1 conserved protein of unknown function compare
PP_4696 -1.1 -1.1 Nitrogen regulation protein NR(I) compare
PP_4482 -1.1 -2.6 Transcriptional regulator, AraC family compare
PP_4094 -1.1 -2.0 conserved protein of unknown function compare
PP_5571 -1.1 -1.4 conserved protein of unknown function compare
PP_1834 -1.1 -2.2 conserved protein of unknown function compare
PP_5505 -1.1 -1.7 conserved transmembrane protein of unknown function compare
PP_1300 -1.1 -2.1 putative amino acid ABC transporter - ATP-binding subunit compare
PP_1827 -1.1 -3.2 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase compare
PP_0111 -1.1 -2.9 Electron transport protein SCO1/SenC compare
PP_2137 -1.1 -1.4 beta-ketoadipyl CoA thiolase, beta component compare
PP_4814 -1.1 -1.8 ATP-dependent protease La domain protein compare
PP_4266 -1.1 -2.4 Adenine phosphoribosyltransferase compare
PP_1404 -1.1 -1.2 conserved protein of unknown function compare
PP_2714 -1.1 -2.5 Sensor histidine kinase compare
PP_0482 -1.1 -3.9 bacterioferritin compare
PP_1825 -1.1 -2.5 conserved exported protein of unknown function compare
PP_0351 -1.1 -3.6 putative Transmembrane sensor protein compare
PP_3417 -1.1 -3.0 D-gluconate transporter compare
PP_3376 -1.1 -3.1 putative phosphonate dehydrogenase compare
PP_2745 -1.1 -1.8 Universal stress protein family compare
PP_3892 -1.1 -0.9 conserved protein of unknown function compare
PP_3453 -1.0 -5.3 putative Sensor protein RstB compare
PP_2326 -1.0 -4.9 Universal stress protein compare
PP_5329 -1.0 -2.7 putative phosphate ABC transporter, periplasmic phosphate-binding protein compare
PP_5328 -1.0 -2.5 putative phosphate transport system permease protein compare
PP_3365 -1.0 -1.1 Acetolactate synthase compare
PP_0435 -1.0 -7.9 Peptidase, M23/M37 family compare
PP_4685 -1.0 -2.8 conserved protein of unknown function compare
PP_1055 -1.0 -0.6 Type II secretion pathway protein GspN compare
PP_4999 -1.0 -0.7 dihydroorotase-like protein compare
PP_2740 -1.0 -1.3 Transcriptional regulator, MerR family compare
PP_0409 -1.0 -4.3 Sensory box histidine kinase compare
PP_4254 -1.0 -1.3 conserved protein of unknown function compare
PP_0126 -1.0 -1.6 Cytochrome c4 compare
PP_1926 -1.0 -1.4 putative phosphotyrosine-protein phosphatase compare
PP_3938 -1.0 -1.5 conserved protein of unknown function compare
PP_4700 -1.0 -1.0 pantothenate synthetase compare
PP_1776 -1.0 -7.4 Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase compare
PP_5659 -1.0 -2.1 protein of unknown function compare
PP_5533 -1.0 -1.1 conserved protein of unknown function compare
PP_3094 -1.0 -2.3 conserved exported protein of unknown function compare
PP_1763 -1.0 -1.1 putative oxidoreductase compare
PP_5008 -1.0 -1.0 Poly granule-associated protein compare
PP_5327 -1.0 -3.1 putative phosphate ABC transporter, permease subunit compare
PP_2388 -1.0 -2.3 Transporter, LysE family compare
PP_4997 -1.0 -1.7 pyrimidine operon regulatory protein/uracil phosphoribosyltransferase compare
PP_0381 -1.0 -3.2 Coenzyme PQQ synthesis protein F compare
PP_3051 -1.0 -2.3 Pyocin R2_PP, tail spike protein compare
PP_2322 -1.0 -4.6 Major outer membrane lipoprotein compare
PP_4701 -1.0 -0.9 glucose-6-phosphate isomerase compare
PP_4881 -0.9 -5.3 putative Iron ABC transporter, periplasmic iron-binding protein compare
PP_5035 -0.9 -2.8 Histidine utilization repressor compare
PP_3971 -0.9 -1.3 conserved protein of unknown function compare
PP_5090 -0.9 -1.1 putative cell division protein compare
PP_2055 -0.9 -2.4 putative isomerase compare
PP_5027 -0.9 -1.4 D-tyrosyl-tRNA(Tyr) deacylase compare
PP_0694 -0.9 -2.2 conserved protein of unknown function compare
PP_0653 -0.9 -1.2 conserved protein of unknown function compare
PP_4418 -0.9 -2.5 conserved protein of unknown function compare
PP_2525 -0.9 -2.5 conserved protein of unknown function compare
PP_5244 -0.9 -2.4 Transcriptional regulator, AraC family compare
PP_5502 -0.9 -2.5 ribosome modulation factor compare
PP_0276 -0.9 -0.9 Transcriptional regulator, Cro/CI family compare
PP_t10 -0.9 -0.7 tRNA-Pro compare
PP_1460 -0.9 -4.6 putative Membrane protein compare
PP_3662 -0.9 -3.1 conserved protein of unknown function compare
PP_2970 -0.9 -2.1 conserved exported protein of unknown function compare
PP_2370 -0.9 -1.2 conserved protein of unknown function compare
PP_5610 -0.9 -1.4 protein of unknown function compare


Specific Phenotypes

For 5 genes in this experiment