Experiment set8IT033 for Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Compare to:

C.elegans, mixed culture-1

200 most important genes:

  gene name fitness t score description  
GFF3901 -7.2 -3.9 Phosphomannomutase (EC 5.4.2.8) compare
GFF2881 -6.9 -10.6 WzxE protein compare
GFF1808 -6.1 -5.9 Mannose-6-phosphate isomerase (EC 5.3.1.8) compare
GFF2880 -6.0 -10.0 4-alpha-L-fucosyltransferase (EC 2.4.1.-) compare
GFF3890 -6.0 -3.4 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) compare
GFF389 -5.9 -4.1 Oligosaccharide repeat unit polymerase Wzy; O-antigen ligase compare
GFF3888 -5.2 -5.1 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
GFF871 -5.2 -14.2 Putative membrane protein compare
GFF2882 -5.0 -10.9 Lipopolysaccharide biosynthesis protein RffA compare
GFF1634 -4.3 -7.1 Lipid A biosynthesis (KDO) 2-(lauroyl)-lipid IVA acyltransferase (EC 2.3.1.-) compare
GFF3667 -4.0 -2.3 Cytidylate kinase (EC 2.7.4.25) compare
GFF4655 -4.0 -4.3 18K peptidoglycan-associated outer membrane lipoprotein; Peptidoglycan-associated lipoprotein precursor; Outer membrane protein P6; OmpA/MotB precursor compare
GFF1303 -3.9 -3.1 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
GFF4653 -3.7 -5.0 TolA protein compare
GFF4639 -3.6 -3.9 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) compare
GFF1716 -3.6 -7.5 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA compare
GFF3712 -3.5 -5.2 Cyclic AMP receptor protein compare
GFF4652 -3.5 -4.1 Tol biopolymer transport system, TolR protein compare
GFF4027 -3.4 -1.6 Flagellar biosynthesis protein FliS compare
GFF115 -3.4 -4.8 Aconitate hydratase 2 (EC 4.2.1.3) @ 2-methylisocitrate dehydratase (EC 4.2.1.99) compare
GFF4654 -3.3 -7.9 tolB protein precursor, periplasmic protein involved in the tonb-independent uptake of group A colicins compare
GFF1256 -3.3 -3.9 Chromosome (plasmid) partitioning protein ParA compare
GFF3415 -3.3 -8.0 Transcriptional regulatory protein PhoP compare
GFF1076 -3.2 -3.4 Aerobic respiration control protein arcA compare
GFF1750 -3.2 -4.8 GTPase and tRNA-U34 5-formylation enzyme TrmE compare
GFF824 -3.2 -4.8 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
GFF4601 -3.1 -10.1 Phosphoglucomutase (EC 5.4.2.2) compare
GFF2475 -3.1 -2.9 Ribonuclease III (EC 3.1.26.3) compare
GFF2690 -3.0 -3.8 Peptide transport system permease protein SapC compare
GFF3887 -3.0 -11.0 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) compare
GFF2943 -3.0 -2.9 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
GFF1411 -2.9 -6.8 Diacylglycerol kinase (EC 2.7.1.107) compare
GFF4353 -2.8 -2.8 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
GFF2991 -2.6 -3.6 Tyrosine recombinase XerD compare
GFF4575 -2.6 -6.0 Magnesium and cobalt efflux protein CorC compare
GFF1737 -2.6 -3.3 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
GFF3414 -2.6 -12.6 Sensor protein PhoQ (EC 2.7.13.3) compare
GFF4890 -2.5 -6.3 Transport ATP-binding protein CydC compare
GFF4354 -2.5 -4.0 ATP-dependent Clp protease ATP-binding subunit ClpX compare
GFF400 -2.5 -2.6 Glutaredoxin 3 (Grx3) compare
GFF2430 -2.4 -2.0 Ferredoxin, 2Fe-2S compare
GFF230 -2.4 -11.0 Adenylate cyclase (EC 4.6.1.1) compare
GFF2431 -2.4 -3.7 Chaperone protein HscA compare
GFF2047 -2.4 -6.2 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) compare
GFF4647 -2.4 -7.8 Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-) compare
GFF3566 -2.3 -3.9 major outer membrane lipoprotein compare
GFF2845 -2.3 -4.8 Tail-specific protease precursor (EC 3.4.21.102) compare
GFF4600 -2.3 -5.4 SeqA protein, negative modulator of initiation of replication compare
GFF2808 -2.2 -10.8 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
GFF633 -2.2 -7.5 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) compare
GFF122 -2.2 -10.2 Pyruvate dehydrogenase E1 component (EC 1.2.4.1) compare
GFF110 -2.2 -9.3 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) compare
GFF4596 -2.2 -2.7 Ferric uptake regulation protein FUR compare
GFF355 -2.2 -3.1 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
GFF3248 -2.1 -5.4 Outer membrane protein A precursor compare
GFF87 -2.1 -2.3 C4-type zinc finger protein, DksA/TraR family compare
GFF4891 -2.1 -6.4 Transport ATP-binding protein CydD compare
GFF1864 -2.1 -1.9 Polymyxin resistance protein PmrM compare
GFF3230 -2.1 -2.4 Transposase compare
GFF629 -2.1 -1.7 Shikimate kinase I (EC 2.7.1.71) compare
GFF391 -2.1 -3.1 ADP-heptose--lipooligosaccharide heptosyltransferase II (EC 2.4.1.-) compare
GFF4642 -2.0 -1.7 Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) compare
GFF236 -2.0 -1.3 FIG00545237: hypothetical protein compare
GFF2409 -2.0 -5.2 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
GFF2434 -2.0 -1.1 Iron-sulfur cluster assembly scaffold protein IscU compare
GFF4636 -2.0 -4.3 Succinate dehydrogenase hydrophobic membrane anchor protein compare
GFF4061 -1.9 -1.2 putative periplasmic protein compare
GFF2348 -1.9 -4.3 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
GFF2213 -1.9 -4.8 Periplasmic thiol:disulfide interchange protein DsbA compare
GFF4646 -1.9 -6.2 Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-) compare
GFF2324 -1.8 -4.1 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) compare
GFF2389 -1.8 -2.5 Trk system potassium uptake protein TrkA compare
GFF4158 -1.8 -2.3 tmRNA-binding protein SmpB compare
GFF20 -1.8 -7.3 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase (EC 3.1.1.-) compare
GFF1502 -1.8 -7.4 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
GFF192 -1.8 -6.8 'Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41)' transl_table=11 compare
GFF55 -1.8 -8.3 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
GFF392 -1.7 -2.8 ADP-L-glycero-D-manno-heptose-6-epimerase (EC 5.1.3.20) compare
GFF597 -1.7 -1.9 DNA-damage-inducible protein J compare
GFF4473 -1.7 -1.6 FIG01046818: hypothetical protein compare
GFF121 -1.7 -3.0 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) compare
GFF1884 -1.7 -2.4 NADH-ubiquinone oxidoreductase chain I (EC 1.6.5.3) compare
GFF3149 -1.7 -9.0 Type I secretion outer membrane protein, TolC precursor compare
GFF4355 -1.7 -1.9 ATP-dependent protease La (EC 3.4.21.53) Type I compare
GFF188 -1.6 -6.3 Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8) compare
GFF4634 -1.6 -5.2 Citrate synthase (si) (EC 2.3.3.1) compare
GFF2773 -1.6 -5.7 Protein-N(5)-glutamine methyltransferase PrmC, methylates polypeptide chain release factors RF1 and RF2 compare
GFF4243 -1.6 -1.2 Probable secreted protein compare
GFF3229 -1.5 -3.9 Secreted effector protein compare
GFF2832 -1.5 -3.4 PTS system, mannose-specific IIC component (EC 2.7.1.69) compare
GFF4638 -1.5 -4.0 Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1) compare
GFF3528 -1.5 -2.5 Integration host factor alpha subunit compare
GFF4637 -1.5 -8.7 Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) compare
GFF2946 -1.5 -4.0 RNA polymerase sigma-54 factor RpoN compare
GFF1032 -1.5 -1.8 DNA polymerase III psi subunit (EC 2.7.7.7) compare
GFF1888 -1.5 -3.6 NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3) compare
GFF3370 -1.5 -2.1 COG1399 protein, clustered with ribosomal protein L32p compare
GFF390 -1.5 -3.0 Lipopolysaccharide heptosyltransferase I (EC 2.4.1.-) compare
GFF1934 -1.4 -3.8 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
GFF357 -1.4 -2.1 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 compare
GFF603 -1.4 -3.1 NfuA Fe-S protein maturation compare
GFF3166 -1.4 -4.1 ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase compare
GFF2478 -1.4 -2.6 leucine-rich repeat protein compare
GFF2433 -1.4 -4.6 Iron binding protein IscA for iron-sulfur cluster assembly compare
GFF158 -1.4 -5.0 Fructose repressor FruR, LacI family compare
GFF2692 -1.3 -4.4 Peptide transport system ATP-binding protein SapF compare
GFF3664 -1.3 -7.3 Phosphoserine aminotransferase (EC 2.6.1.52) compare
GFF1879 -1.3 -9.1 NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3) compare
GFF2840 -1.3 -2.2 Putative inner membrane protein compare
GFF1881 -1.3 -6.7 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
GFF635 -1.3 -4.5 Tryptophanyl-tRNA synthetase (EC 6.1.1.2) compare
GFF522 -1.3 -5.7 Low-affinity inorganic phosphate transporter compare
GFF1885 -1.3 -6.1 NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3) compare
GFF2392 -1.3 -1.7 Peptide deformylase (EC 3.5.1.88) compare
GFF2689 -1.3 -4.8 Peptide transport system permease protein SapB compare
GFF1499 -1.2 -3.2 Ribosome-binding factor A compare
GFF2994 -1.2 -1.8 YgfY COG2938 compare
GFF2223 -1.2 -4.2 GTP-binding protein TypA/BipA compare
GFF1887 -1.2 -6.4 NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3) compare
GFF2477 -1.2 -5.1 Translation elongation factor LepA compare
GFF825 -1.2 -1.8 RNA-binding protein Hfq compare
GFF4641 -1.2 -2.4 Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5) compare
GFF1891 -1.2 -2.7 NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3) compare
GFF4635 -1.2 -2.1 Succinate dehydrogenase cytochrome b-556 subunit compare
GFF2481 -1.2 -4.9 hypothetical protein compare
GFF1312 -1.2 -2.8 'Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-)' transl_table=11 compare
GFF1953 -1.2 -2.8 Phosphohistidine phosphatase SixA compare
GFF1735 -1.2 -4.5 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
GFF630 -1.1 -5.0 3-dehydroquinate synthase (EC 4.2.3.4) compare
GFF276 -1.1 -4.4 Potassium uptake protein TrkH compare
GFF2216 -1.1 -5.0 DNA polymerase I (EC 2.7.7.7) compare
GFF332 -1.1 -2.7 Mg(2+) transport ATPase protein C compare
GFF1886 -1.1 -5.9 NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3) compare
GFF1890 -1.1 -7.4 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
GFF1882 -1.1 -5.2 NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3) compare
GFF1880 -1.1 -6.1 NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3) compare
GFF492 -1.1 -2.6 Endoglucanase precursor (EC 3.2.1.4) compare
GFF1889 -1.1 -7.1 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
GFF2915 -1.1 -2.5 Preprotein translocase subunit SecG (TC 3.A.5.1.1) compare
GFF1090 -1.1 -2.1 Chaperone protein DnaJ compare
GFF2182 -1.1 -3.7 Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) compare
GFF3227 -1.1 -4.8 Phage tail fiber protein compare
GFF2148 -1.1 -2.4 Arginine pathway regulatory protein ArgR, repressor of arg regulon compare
GFF4387 -1.0 -1.6 Adenine phosphoribosyltransferase (EC 2.4.2.7) compare
GFF2149 -1.0 -5.3 Malate dehydrogenase (EC 1.1.1.37) compare
GFF1921 -1.0 -2.6 3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX (EC 4.1.1.-) compare
GFF1472 -1.0 -1.6 Transcriptional regulator of catabolic arginine decarboxylase (adiA) compare
GFF214 -1.0 -5.2 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) compare
GFF4060 -1.0 -1.0 putative cytoplasmic protein compare
GFF632 -1.0 -4.0 Methyl-directed repair DNA adenine methylase (EC 2.1.1.72) compare
GFF2784 -1.0 -2.0 GTP-binding and nucleic acid-binding protein YchF compare
GFF3231 -1.0 -6.7 Gifsy-2 prophage protein compare
GFF3548 -1.0 -4.2 3-dehydroquinate dehydratase I (EC 4.2.1.10) compare
GFF2349 -1.0 -3.6 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
GFF3139 -1.0 -6.4 Sensory histidine kinase QseC compare
GFF1883 -1.0 -4.8 NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3) compare
GFF3518 -1.0 -1.5 putative outer membrane protein compare
GFF2954 -1.0 -5.6 Aerobic respiration control sensor protein arcB (EC 2.7.3.-) compare
GFF4650 -1.0 -2.3 4-hydroxybenzoyl-CoA thioesterase family active site compare
GFF4865 -1.0 -4.4 Glycine cleavage system transcriptional activator GcvA compare
GFF1734 -1.0 -3.8 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
GFF1936 -1.0 -5.3 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) compare
GFF4830 -1.0 -1.3 hypothetical protein compare
GFF2656 -1.0 -4.1 Fumarate and nitrate reduction regulatory protein compare
GFF1000 -1.0 -2.2 Type I restriction-modification system, specificity subunit S (EC 3.1.21.3) compare
GFF401 -1.0 -2.5 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
GFF1900 -0.9 -4.9 Acetate kinase (EC 2.7.2.1) compare
GFF2968 -0.9 -3.0 Stringent starvation protein A compare
GFF2145 -0.9 -0.8 probable ribonuclease inhibitor YPO3690 compare
GFF2620 -0.9 -1.1 FIG01045674: hypothetical protein compare
GFF3862 -0.9 -3.5 Deoxycytidine triphosphate deaminase (EC 3.5.4.13) compare
GFF1264 -0.9 -1.2 putative cytoplasmic protein compare
GFF2173 -0.9 -3.5 Chromosomal replication initiator protein DnaA compare
GFF1095 -0.9 -0.9 Putative membrane protein compare
GFF213 -0.9 -4.1 Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) compare
GFF829 -0.9 -1.0 Putative inner membrane protein YjeT (clustered with HflC) compare
GFF3228 -0.9 -3.8 Phage tail fibers compare
GFF3656 -0.9 -3.5 Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) compare
GFF2973 -0.9 -3.3 Putative cytochrome d ubiquinol oxidase subunit III (EC 1.10.3.-) (Cytochrome bd-I oxidase subunit III) compare
GFF190 -0.8 -2.3 SSU rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase (EC 2.1.1.182) compare
GFF2085 -0.8 -1.5 Ethanolamine utilization polyhedral-body-like protein EutS compare
GFF4026 -0.8 -1.3 Flagellar biosynthesis protein FliT compare
GFF4892 -0.8 -3.2 Thioredoxin reductase (EC 1.8.1.9) compare
GFF796 -0.8 -2.5 Phage outer membrane lytic protein Rz; Endopeptidase (EC 3.4.-.-) compare
GFF1281 -0.8 -1.5 Head decoration protein compare
GFF536 -0.8 -5.7 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
GFF109 -0.8 -1.5 DeoR family transcriptional regulator probably related to glycerate, glycolaldehyde metabolism compare
GFF4256 -0.8 -1.1 putative Cytochrome bd2, subunit II compare
GFF3377 -0.8 -2.9 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41) compare
GFF2992 -0.8 -4.5 Flavodoxin 2 compare
GFF2283 -0.8 -4.9 6-phosphofructokinase (EC 2.7.1.11) compare
GFF416 -0.8 -4.0 Mannitol operon repressor compare
GFF778 -0.8 -0.7 Mobile element protein compare
GFF2160 -0.8 -1.5 'Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain' transl_table=11 compare
GFF799 -0.8 -3.6 FIG01045807: hypothetical protein compare
GFF3669 -0.8 -1.7 Integration host factor beta subunit compare
GFF2050 -0.8 -3.6 Pyridoxal kinase (EC 2.7.1.35) compare
GFF1799 -0.8 -2.7 Putative inner membrane protein compare
GFF1901 -0.8 -3.6 Phosphate acetyltransferase (EC 2.3.1.8) compare
GFF1966 -0.8 -0.9 FIG00638164: hypothetical protein compare


Specific Phenotypes

None in this experiment

For Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 in micoeukaryotes experiments

For micoeukaryotes Pelleted after growth overnight in LB+Kan50 across organisms