Experiment set86S600 for Escherichia coli BW25113

Compare to:

NophageCTRB12

200 most important genes:

  gene name fitness t score description  
b1192 ldcA -3.1 -4.2 L,D-carboxypeptidase A (NCBI) compare
b0142 folK -3.0 -0.6 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b4458 oxyS -2.9 -0.7 global regulatory RNA (NCBI) compare
b3649 rpoZ -2.8 -2.9 DNA-directed RNA polymerase subunit omega (NCBI) compare
b0683 fur -2.8 -0.9 ferric uptake regulator (NCBI) compare
b1231 tyrT -2.8 -0.7 tRNA-Tyr (NCBI) compare
b3839 tatC -2.7 -6.3 TatABCE protein translocation system subunit (NCBI) compare
b3977 tyrU -2.6 -0.5 tRNA-Tyr (NCBI) compare
b3961 oxyR -2.6 -9.8 DNA-binding transcriptional dual regulator (NCBI) compare
b3341 rpsG -2.6 -0.8 30S ribosomal protein S7 (NCBI) compare
b1882 cheY -2.5 -0.5 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b4655 ythA -2.3 -1.0 expressed protein (RefSeq) compare
b2259 pmrD -2.3 -0.7 polymyxin resistance protein B (VIMSS) compare
b1104 ycfL -2.3 -1.2 hypothetical protein (NCBI) compare
b2051 wcaH -2.2 -1.1 GDP-mannose mannosyl hydrolase (VIMSS) compare
b0018 mokC -2.1 -0.9 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b1480 sra -2.1 -0.9 30S ribosomal subunit protein S22 (NCBI) compare
b1273 yciN -1.9 -0.9 hypothetical protein (NCBI) compare
b0605 ahpC -1.9 -3.4 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b1572 ydfB -1.9 -1.0 orf, hypothetical protein (VIMSS) compare
b0737 tolQ -1.9 -1.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0902 pflA -1.9 -5.1 pyruvate formate lyase activating enzyme 1 (NCBI) compare
b1370 insH-5 -1.9 -1.3 Rac prophage; IS5 transposase and trans-activator (NCBI) compare
b0990 cspG -1.8 -0.6 DNA-binding transcriptional regulator (NCBI) compare
b2904 gcvH -1.8 -1.4 glycine cleavage system protein H (NCBI) compare
b1563 relE -1.8 -1.3 Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) compare
b3052 rfaE -1.8 -3.9 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3778 rep -1.7 -6.1 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b1667 ydhR -1.7 -1.6 hypothetical protein (NCBI) compare
b0903 pflB -1.7 -7.2 pyruvate formate lyase I (NCBI) compare
b4529 ydbJ -1.7 -0.6 hypothetical protein (NCBI) compare
b4551 yheV -1.7 -1.5 hypothetical protein (NCBI) compare
b4163 glyV -1.6 -0.9 tRNA-Gly (NCBI) compare
b0888 trxB -1.6 -2.5 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b3387 dam -1.6 -8.0 DNA adenine methylase (NCBI) compare
b4613 dinQ -1.6 -1.0 Damage inducible, function unknown (RefSeq) compare
b0767 ybhE -1.5 -2.7 6-phosphogluconolactonase (NCBI) compare
b3162 deaD -1.5 -2.5 inducible ATP-independent RNA helicase (VIMSS) compare
b1269 rluB -1.5 -2.2 23S rRNA pseudouridylate synthase (NCBI) compare
b4402 yjjY -1.5 -0.5 hypothetical protein (NCBI) compare
b1841 yobA -1.5 -1.1 hypothetical protein (NCBI) compare
b1307 pspD -1.5 -0.9 peripheral inner membrane phage-shock protein (NCBI) compare
b0740 tolB -1.5 -2.3 translocation protein TolB precursor (NCBI) compare
b0547 ybcN -1.5 -2.4 DLP12 prophage; predicted protein (NCBI) compare
b3601 mtlR -1.5 -4.1 DNA-binding repressor (NCBI) compare
b1279 yciS -1.5 -0.6 conserved inner membrane protein (NCBI) compare
b2287 nuoB -1.5 -2.7 NADH dehydrogenase subunit B (NCBI) compare
b2947 gshB -1.5 -2.5 glutathione synthetase (NCBI) compare
b0782 moaB -1.4 -1.2 molybdopterin biosynthesis protein B (NCBI) compare
b4571 wbbL -1.4 -1.9 no description compare
b1709 btuD -1.4 -0.5 vitamin B12-transporter ATPase (NCBI) compare
b1419 ydcA -1.4 -3.4 hypothetical protein (NCBI) compare
b3636 rpmG -1.4 -0.7 50S ribosomal protein L33 (NCBI) compare
b0014 dnaK -1.4 -0.9 molecular chaperone DnaK (NCBI) compare
b3842 rfaH -1.4 -3.8 transcriptional activator RfaH (NCBI) compare
b2808 gcvA -1.4 -2.7 DNA-binding transcriptional dual regulator (NCBI) compare
b4178 yjeB -1.4 -3.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b1183 umuD -1.4 -1.1 DNA polymerase V, subunit D (NCBI) compare
b2553 glnB -1.4 -3.5 regulatory protein P-II for glutamine synthetase (NCBI) compare
b0080 fruR -1.4 -4.5 DNA-binding transcriptional dual regulator (NCBI) compare
b2284 nuoF -1.4 -3.1 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b1658 purR -1.4 -3.4 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b3164 pnp -1.4 -1.8 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b3026 qseC -1.4 -2.3 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b2569 lepA -1.4 -2.7 GTP-binding protein LepA (NCBI) compare
b1839 yebY -1.4 -2.2 hypothetical protein (NCBI) compare
b3390 aroK -1.4 -1.2 shikimate kinase I (NCBI) compare
b2082 ogrK -1.4 -1.8 DNA-binding transcriptional regulator prophage P2 remnant (NCBI) compare
b4413 sokC -1.4 -0.7 regulatory antisense RNA (NCBI) compare
b1236 galU -1.3 -2.9 glucose-1-phosphate uridylyltransferase (NCBI) compare
b0386 proC -1.3 -2.8 pyrroline-5-carboxylate reductase (NCBI) compare
b4320 fimH -1.3 -7.6 minor component of type 1 fimbriae (NCBI) compare
b2288 nuoA -1.3 -2.0 NADH dehydrogenase I chain A (VIMSS) compare
b2318 truA -1.3 -2.1 tRNA pseudouridine synthase A (NCBI) compare
b1358 ydaT -1.3 -0.7 Rac prophage; predicted protein (NCBI) compare
b1739 osmE -1.3 -1.5 DNA-binding transcriptional activator (NCBI) compare
b3075 ebgR -1.3 -3.7 DNA-binding transcriptional repressor (NCBI) compare
b3784 rfe -1.3 -7.0 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b0721 sdhC -1.3 -2.4 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b0741 pal -1.3 -2.1 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b0101 yacG -1.3 -2.2 zinc-binding protein (NCBI) compare
b0696 kdpC -1.3 -1.9 potassium-transporting ATPase subunit C (NCBI) compare
b1487 ddpA -1.3 -3.3 D-ala-D-a la transporter subunit (NCBI) compare
b2187 yejL -1.3 -1.5 hypothetical protein (NCBI) compare
b0688 pgm -1.3 -2.2 phosphoglucomutase (NCBI) compare
b0617 citD -1.3 -0.9 citrate lyase, acyl carrier (gamma) subunit (NCBI) compare
b0739 tolA -1.3 -1.7 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3500 gor -1.2 -0.6 glutathione reductase (NCBI) compare
b1293 sapB -1.2 -0.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3183 obgE -1.2 -0.4 GTPase involved in cell partioning and DNA repair (NCBI) compare
b3791 rffA -1.2 -3.8 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b0222 lpcA -1.2 -1.5 phosphoheptose isomerase (NCBI) compare
b2990 hybG -1.2 -1.2 hydrogenase 2 accessory protein (NCBI) compare
b1575 dicB -1.2 -0.6 Qin prophage; cell division inhibition protein (NCBI) compare
b3237 argR -1.2 -2.2 arginine repressor (NCBI) compare
b1103 ycfF -1.2 -0.6 orf, hypothetical protein (VIMSS) compare
b2272 yfbM -1.2 -1.9 hypothetical protein (NCBI) compare
b1685 ydiH -1.2 -0.7 predicted protein (RefSeq) compare
b4203 rplI -1.2 -2.3 50S ribosomal protein L9 (NCBI) compare
b2707 srlR -1.2 -3.4 DNA-bindng transcriptional repressor (NCBI) compare
b3973 birA -1.2 -1.2 biotin--protein ligase (NCBI) compare
b1999 yeeP -1.2 -2.0 putative histone (VIMSS) compare
b0015 dnaJ -1.2 -5.1 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b3844 fre -1.2 -3.8 NAD(P)H-flavin reductase (NCBI) compare
b1306 pspC -1.1 -1.1 DNA-binding transcriptional activator (NCBI) compare
b1418 cybB -1.1 -2.0 cytochrome b(561) (VIMSS) compare
b0051 ksgA -1.1 -3.0 dimethyladenosine transferase (NCBI) compare
b1744 astE -1.1 -3.5 succinylglutamate desuccinylase (NCBI) compare
b0730 mngR -1.1 -0.8 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b1368 ynaA -1.1 -1.3 Rac prophage; predicted tail protein (RefSeq) compare
b1855 lpxM -1.1 -2.0 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b3250 mreC -1.1 -0.9 cell wall structural complex MreBCD transmembrane component MreC (NCBI) compare
b1217 chaB -1.1 -0.6 cation transport regulator (NCBI) compare
b3226 yhcK -1.1 -3.1 putative FADA-type transcriptional regulator (VIMSS) compare
b1724 ydiZ -1.1 -0.9 hypothetical protein (NCBI) compare
b1557 cspB -1.1 -0.9 Qin prophage; cold shock protein (NCBI) compare
b1973 yodA -1.1 -2.4 conserved metal-binding protein (NCBI) compare
b1523 yneG -1.1 -0.7 hypothetical protein (NCBI) compare
b0429 cyoD -1.1 -3.0 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b0904 focA -1.1 -3.7 formate transporter (NCBI) compare
b1292 sapC -1.1 -1.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2498 upp -1.1 -1.4 uracil phosphoribosyltransferase (VIMSS) compare
b0677 nagA -1.1 -3.7 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b3792 wzxE -1.1 -4.4 O-antigen translocase (NCBI) compare
b1074 flgC -1.1 -1.0 flagellar basal-body rod protein C (NCBI) compare
b4180 rlmB -1.1 -4.1 23S rRNA (Gm2251)-methyltransferase (NCBI) compare
b0471 ybaB -1.1 -1.5 hypothetical protein (NCBI) compare
b3259 prmA -1.1 -2.7 ribosomal protein L11 methyltransferase (NCBI) compare
b3726 pstA -1.0 -2.9 phosphate transporter subunit (NCBI) compare
b1263 trpD -1.0 -1.1 bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) compare
b3620 rfaF -1.0 -2.9 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b4436 ryeC -1.0 -0.7 Novel sRNA, function unknown; paralogous to the other QUAD sRNA genes unknown (RefSeq) compare
b3613 yibP -1.0 -1.6 putative membrane protein (VIMSS) compare
b4538 yoeF -1.0 -0.6 hypothetical protein (RefSeq) compare
b3911 cpxA -1.0 -4.8 two-component sensor protein (NCBI) compare
b1764 selD -1.0 -2.5 selenophosphate synthetase (NCBI) compare
b1823 cspC -1.0 -0.9 stress protein, member of the CspA-family (NCBI) compare
b4547 ypfN -1.0 -1.7 hypothetical protein (NCBI) compare
b3002 yqhA -1.0 -0.9 hypothetical protein (NCBI) compare
b4453 ldrD -1.0 -1.1 toxic polypeptide, small (NCBI) compare
b0962 helD -1.0 -3.0 DNA helicase IV (NCBI) compare
b3999 yjaG -1.0 -2.8 hypothetical protein (NCBI) compare
b1524 yneH -1.0 -0.3 predicted glutaminase (NCBI) compare
b0920 ycbC -1.0 -2.2 conserved inner membrane protein (NCBI) compare
b3672 ivbL -1.0 -2.0 ilvB operon leader peptide (NCBI) compare
b2876 b2876 -1.0 -3.7 orf, hypothetical protein (VIMSS) compare
b4312 fimB -1.0 -6.0 tyrosine recombinase/inversion of on/off regulator of fimA (NCBI) compare
b4317 fimD -1.0 -8.9 outer membrane usher protein, type 1 fimbrial synthesis (NCBI) compare
b1539 ydfG -1.0 -1.8 L-allo-threonine dehydrogenase, NAD(P)-binding (NCBI) compare
b3631 rfaG -1.0 -6.8 glucosyltransferase I (NCBI) compare
b4375 prfC -1.0 -2.7 peptide chain release factor 3 (NCBI) compare
b1126 potA -1.0 -3.1 putrescine/spermidine ABC transporter ATPase protein (NCBI) compare
b2343 b2343 -1.0 -0.6 orf, hypothetical protein (VIMSS) compare
b3786 rffE -1.0 -5.4 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b3761 trpT -1.0 -0.5 tRNA-Trp (NCBI) compare
b4544 yfbW -1.0 -1.7 hypothetical protein (NCBI) compare
b3042 b3042 -1.0 -1.9 orf, hypothetical protein (VIMSS) compare
b0053 surA -1.0 -1.7 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b4522 yciX_1 -1.0 -1.2 hypothetical protein (NCBI) compare
b0723 sdhA -0.9 -5.6 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b0439 lon -0.9 -2.9 DNA-binding ATP-dependent protease La (NCBI) compare
b4102 phnF -0.9 -2.9 predicted DNA-binding transcriptional regulator of phosphonate uptake and biodegradation (NCBI) compare
b3169 nusA -0.9 -1.4 transcription elongation factor NusA (NCBI) compare
b3933 ftsN -0.9 -3.9 essential cell division protein (NCBI) compare
b2783 chpR -0.9 -1.1 antitoxin of the ChpA-ChpR toxin-antitoxin system (NCBI) compare
b0728 sucC -0.9 -3.4 succinyl-CoA synthetase subunit beta (NCBI) compare
b0676 nagC -0.9 -4.1 DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine (NCBI) compare
b1710 btuE -0.9 -1.5 predicted glutathione peroxidase (NCBI) compare
b3035 tolC -0.9 -4.1 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b0623 cspE -0.9 -0.7 cold shock protein E (NCBI) compare
b2501 ppk -0.9 -3.7 polyphosphate kinase (NCBI) compare
b1423 ydcJ -0.9 -1.1 hypothetical protein (NCBI) compare
b3493 pitA -0.9 -3.8 phosphate transporter, low-affinity (NCBI) compare
b2007 yeeX -0.9 -1.6 conserved protein (RefSeq) compare
b3609 secB -0.9 -1.4 export protein SecB (NCBI) compare
b2175 spr -0.9 -1.8 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b1176 minC -0.9 -1.2 septum formation inhibitor (NCBI) compare
b0864 artP -0.9 -1.5 arginine transporter subunit (NCBI) compare
b1355 b1355 -0.9 -1.6 orf, hypothetical protein (VIMSS) compare
b1362 rzpR -0.9 -1.0 putative Rac prophage endopeptidase (VIMSS) compare
b4025 pgi -0.9 -4.0 glucose-6-phosphate isomerase (NCBI) compare
b4353 yjiX -0.9 -2.7 hypothetical protein (NCBI) compare
b2528 iscA -0.9 -0.6 iron-sulfur cluster assembly protein (NCBI) compare
b4513 kdpF -0.9 -1.0 potassium ion accessory transporter subunit (NCBI) compare
b2285 nuoE -0.9 -0.9 NADH dehydrogenase subunit E (NCBI) compare
b1138 ymfE -0.9 -0.5 e14 prophage; predicted inner membrane protein (NCBI) compare
b2894 xerD -0.9 -0.4 site-specific tyrosine recombinase XerD (NCBI) compare
b4202 rpsR -0.9 -0.4 30S ribosomal protein S18 (NCBI) compare
b2683 ygaH -0.9 -2.6 predicted inner membrane protein (NCBI) compare
b1225 narH -0.9 -2.6 nitrate reductase 1, beta (Fe-S) subunit (NCBI) compare
b1630 rsxD -0.9 -2.5 electron transport complex protein RnfD (NCBI) compare
b0183 rnhB -0.9 -1.5 ribonuclease HII (NCBI) compare
b2488 hyfH -0.9 -1.3 hydrogenase 4, Fe-S subunit (NCBI) compare
b3995 rsd -0.9 -3.0 stationary phase protein, binds sigma 70 RNA polymerase subunit (NCBI) compare
b0440 hupB -0.9 -2.0 HU, DNA-binding transcriptional regulator, beta subunit (NCBI) compare
b0866 ybjQ -0.9 -0.5 hypothetical protein (NCBI) compare
b1853 yebK -0.9 -1.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b4232 fbp -0.9 -4.6 fructose-1,6-bisphosphatase (NCBI) compare
b1729 ydjN -0.9 -1.8 predicted transporter (NCBI) compare
b3021 ygiT -0.9 -0.6 predicted DNA-binding transcriptional regulator (NCBI) compare


Specific Phenotypes

For 3 genes in this experiment

For no phage control No phage in Escherichia coli BW25113

For no phage control No phage across organisms