Experiment set85S301 for Escherichia coli BW25113

Compare to:

Bas96

200 most important genes:

  gene name fitness t score description  
b0222 lpcA -3.1 -4.1 phosphoheptose isomerase (NCBI) compare
b3816 corA -3.1 -11.4 magnesium/nickel/cobalt transporter (NCBI) compare
b0053 surA -2.8 -4.6 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b2620 smpB -2.7 -1.8 SsrA-binding protein (NCBI) compare
b1291 sapD -2.7 -1.9 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1882 cheY -2.5 -1.0 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b1861 ruvA -2.4 -2.8 Holliday junction DNA helicase motor protein (NCBI) compare
b1860 ruvB -2.2 -2.5 Holliday junction DNA helicase B (NCBI) compare
b3811 xerC -2.1 -1.5 site-specific tyrosine recombinase XerC (NCBI) compare
b3778 rep -2.1 -8.4 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b3183 obgE -2.0 -1.4 GTPase involved in cell partioning and DNA repair (NCBI) compare
b2284 nuoF -2.0 -5.0 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b4042 dgkA -1.9 -1.8 diacylglycerol kinase (NCBI) compare
b3169 nusA -1.9 -3.3 transcription elongation factor NusA (NCBI) compare
b2283 nuoG -1.8 -8.0 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b2567 rnc -1.8 -1.2 ribonuclease III (NCBI) compare
b0049 apaH -1.8 -2.9 diadenosinetetraphosphatase (NCBI) compare
b2276 nuoN -1.7 -5.1 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b1286 rnb -1.7 -3.1 exoribonuclease II (NCBI) compare
b0739 tolA -1.7 -3.6 cell envelope integrity inner membrane protein TolA (NCBI) compare
b2168 fruK -1.7 -2.0 1-phosphofructokinase (NCBI) compare
b3636 rpmG -1.6 -2.0 50S ribosomal protein L33 (NCBI) compare
b3405 ompR -1.6 -4.8 osmolarity response regulator (NCBI) compare
b2278 nuoL -1.6 -7.8 NADH dehydrogenase subunit L (NCBI) compare
b0439 lon -1.5 -5.2 DNA-binding ATP-dependent protease La (NCBI) compare
b0737 tolQ -1.5 -2.8 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0630 lipB -1.5 -1.4 protein of lipoate biosynthesis (VIMSS) compare
b2282 nuoH -1.5 -2.9 NADH dehydrogenase subunit H (NCBI) compare
b2330 yfcB -1.5 -2.5 putative adenine-specific methylase (VIMSS) compare
b0890 ftsK -1.5 -3.8 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2277 nuoM -1.5 -6.2 NADH dehydrogenase subunit M (NCBI) compare
b0740 tolB -1.5 -3.9 translocation protein TolB precursor (NCBI) compare
b3500 gor -1.4 -1.9 glutathione reductase (NCBI) compare
b2280 nuoJ -1.4 -4.6 NADH dehydrogenase subunit J (NCBI) compare
b2281 nuoI -1.4 -3.1 NADH dehydrogenase subunit I (NCBI) compare
b2518 ndk -1.3 -2.9 nucleoside diphosphate kinase (NCBI) compare
b2287 nuoB -1.3 -2.5 NADH dehydrogenase subunit B (NCBI) compare
b1164 ycgZ -1.3 -2.0 hypothetical protein (NCBI) compare
b2498 upp -1.3 -2.7 uracil phosphoribosyltransferase (VIMSS) compare
b2285 nuoE -1.3 -2.0 NADH dehydrogenase subunit E (NCBI) compare
b3844 fre -1.3 -5.7 NAD(P)H-flavin reductase (NCBI) compare
b3863 polA -1.3 -1.6 DNA polymerase I (NCBI) compare
b1176 minC -1.3 -3.3 septum formation inhibitor (NCBI) compare
b0726 sucA -1.3 -4.0 alpha-ketoglutarate decarboxylase (NCBI) compare
b0683 fur -1.3 -1.2 ferric uptake regulator (NCBI) compare
b3390 aroK -1.3 -1.9 shikimate kinase I (NCBI) compare
b3026 qseC -1.3 -3.6 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b2286 nuoC -1.2 -3.8 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b4458 oxyS -1.1 -1.4 global regulatory RNA (NCBI) compare
b1259 yciG -1.1 -2.1 orf, hypothetical protein (VIMSS) compare
b3806 cyaA -1.1 -4.4 adenylate cyclase (NCBI) compare
b3021 ygiT -1.1 -1.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b2288 nuoA -1.1 -2.7 NADH dehydrogenase I chain A (VIMSS) compare
b0721 sdhC -1.1 -4.9 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b2895 fldB -1.1 -2.8 flavodoxin 2 (NCBI) compare
b3706 trmE -1.1 -3.5 tRNA modification GTPase (NCBI) compare
b1361 ydaW -1.0 -0.7 orf, hypothetical protein (VIMSS) compare
b0438 clpX -1.0 -4.7 ATP-dependent protease ATP-binding subunit (NCBI) compare
b1600 mdtJ -1.0 -2.0 multidrug efflux system transporter (NCBI) compare
b3839 tatC -1.0 -3.8 TatABCE protein translocation system subunit (NCBI) compare
b2279 nuoK -1.0 -1.0 NADH dehydrogenase subunit K (NCBI) compare
b4139 aspA -1.0 -6.7 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b4146 yjeK -1.0 -1.7 predicted lysine aminomutase (NCBI) compare
b1951 rcsA -1.0 -1.1 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b3613 yibP -1.0 -2.5 putative membrane protein (VIMSS) compare
b0722 sdhD -1.0 -2.9 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b3236 mdh -1.0 -5.4 malate dehydrogenase (NCBI) compare
b1175 minD -1.0 -4.1 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b0888 trxB -1.0 -2.4 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b4538 yoeF -0.9 -1.7 hypothetical protein (RefSeq) compare
b1105 ycfM -0.9 -3.7 predicted outer membrane lipoprotein (NCBI) compare
b0357 yaiN -0.9 -1.7 putative alpha helix chain (VIMSS) compare
b0723 sdhA -0.9 -6.4 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b1527 yneK -0.9 -1.7 hypothetical protein (NCBI) compare
b2830 nudH -0.9 -0.6 dinucleoside polyphosphate hydrolase (NCBI) compare
b3621 rfaC -0.9 -3.3 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b2897 ygfY -0.9 -1.5 hypothetical protein (NCBI) compare
b1160 elbA -0.9 -1.1 hypothetical protein (NCBI) compare
b0720 gltA -0.9 -4.0 citrate synthase (NCBI) compare
b2504 yfgG -0.9 -1.2 Negative regulator of nickel and cobalt uptake (YfgG) (from data) compare
b2894 xerD -0.9 -1.3 site-specific tyrosine recombinase XerD (NCBI) compare
b4647 mokA -0.9 -0.8 no description compare
b3052 rfaE -0.9 -3.0 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3620 rfaF -0.9 -3.1 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b2501 ppk -0.9 -5.2 polyphosphate kinase (NCBI) compare
b3443 yrhA -0.9 -1.3 orf, hypothetical protein (VIMSS) compare
b0965 b0965 -0.8 -1.2 orf, hypothetical protein (VIMSS) compare
b3619 rfaD -0.8 -1.9 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b2318 truA -0.8 -2.1 tRNA pseudouridine synthase A (NCBI) compare
b3658 selC -0.8 -2.6 tRNA-Sec (NCBI) compare
b1183 umuD -0.8 -1.2 DNA polymerase V, subunit D (NCBI) compare
b3741 gidA -0.8 -2.3 glucose-inhibited division protein A (NCBI) compare
b3916 pfkA -0.8 -1.5 6-phosphofructokinase (NCBI) compare
b2650 ypjC -0.8 -0.4 hypothetical protein (RefSeq) compare
b4513 kdpF -0.8 -2.3 potassium ion accessory transporter subunit (NCBI) compare
b4685 yrbN -0.8 -1.9 expressed protein (RefSeq) compare
b0200 gmhB -0.8 -0.9 hypothetical protein (NCBI) compare
b4557 yidD -0.8 -1.9 hypothetical protein (NCBI) compare
b1159 mcrA -0.8 -1.2 e14 prophage; 5-methylcytosine-specific restriction endonuclease B (NCBI) compare
b1863 ruvC -0.8 -1.3 Holliday junction resolvase (NCBI) compare
b2935 tktA -0.8 -1.2 transketolase 1, thiamin-binding (NCBI) compare
b1855 lpxM -0.8 -2.9 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b0728 sucC -0.8 -4.3 succinyl-CoA synthetase subunit beta (NCBI) compare
b1712 ihfA -0.8 -1.1 integration host factor subunit alpha (NCBI) compare
b0724 sdhB -0.8 -4.2 succinate dehydrogenase, FeS subunit (NCBI) compare
b0738 tolR -0.8 -1.9 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3414 gntY -0.8 -2.6 predicted gluconate transport associated protein (NCBI) compare
b0149 mrcB -0.8 -5.7 penicillin-binding protein 1b (NCBI) compare
b2579 yfiD -0.7 -1.5 pyruvate formate lyase subunit (NCBI) compare
b4202 rpsR -0.7 -1.0 30S ribosomal protein S18 (NCBI) compare
b0080 fruR -0.7 -3.1 DNA-binding transcriptional dual regulator (NCBI) compare
b3609 secB -0.7 -2.5 export protein SecB (NCBI) compare
b4172 hfq -0.7 -0.5 RNA-binding protein Hfq (NCBI) compare
b4481 rffT -0.7 -3.6 4-alpha-L-fucosyltransferase (NCBI) compare
b2569 lepA -0.7 -2.4 GTP-binding protein LepA (NCBI) compare
b3281 aroE -0.7 -5.7 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b1084 rne -0.7 -3.4 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b0741 pal -0.7 -2.2 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b1594 dgsA -0.7 -2.2 DNA-binding transcriptional repressor (NCBI) compare
b4179 vacB -0.7 -3.1 putative enzyme (VIMSS) compare
b4388 serB -0.7 -4.5 3-phosphoserine phosphatase (NCBI) compare
b3387 dam -0.7 -5.3 DNA adenine methylase (NCBI) compare
b1357 ydaS -0.7 -1.8 Rac prophage; predicted DNA-binding transcriptional regulator (NCBI) compare
b4676 yoaK -0.7 -0.4 expressed protein (RefSeq) compare
b3162 deaD -0.7 -2.6 inducible ATP-independent RNA helicase (VIMSS) compare
b2911 ssrS -0.7 -1.4 6S regulatory RNA (NCBI) compare
b4493 gapC -0.7 -1.9 no description compare
b0428 cyoE -0.7 -3.6 protoheme IX farnesyltransferase (NCBI) compare
b3849 trkH -0.7 -4.7 potassium transporter (NCBI) compare
b1793 yoaF -0.7 -2.1 conserved outer membrane protein (NCBI) compare
b0386 proC -0.7 -2.1 pyrroline-5-carboxylate reductase (NCBI) compare
b1192 ldcA -0.7 -2.6 L,D-carboxypeptidase A (NCBI) compare
b1143 ymfI -0.7 -1.6 orf, hypothetical protein (VIMSS) compare
b1804 rnd -0.7 -2.1 ribonuclease D (NCBI) compare
b0431 cyoB -0.7 -4.8 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b3237 argR -0.7 -2.1 arginine repressor (NCBI) compare
b0247 ykfG -0.7 -1.0 CP4-6 prophage; predicted DNA repair protein (NCBI) compare
b2597 yfiA -0.7 -1.4 cold shock protein associated with 30S ribosomal subunit (NCBI) compare
b0989 cspH -0.7 -1.8 stress protein, member of the CspA-family (NCBI) compare
b1001 yccE -0.7 -0.4 hypothetical protein (NCBI) compare
b4178 yjeB -0.6 -2.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b0677 nagA -0.6 -2.7 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b0471 ybaB -0.6 -1.6 hypothetical protein (NCBI) compare
b0623 cspE -0.6 -1.4 cold shock protein E (NCBI) compare
b1709 btuD -0.6 -0.6 vitamin B12-transporter ATPase (NCBI) compare
b1613 manA -0.6 -1.5 mannose-6-phosphate isomerase (VIMSS) compare
b0454 ybaZ -0.6 -2.4 predicted methyltransferase (NCBI) compare
b3075 ebgR -0.6 -2.3 DNA-binding transcriptional repressor (NCBI) compare
b2646 ypjF -0.6 -1.1 CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system (NCBI) compare
b3068 ygjF -0.6 -2.0 G/U mismatch-specific DNA glycosylase (NCBI) compare
b2906 visC -0.6 -3.0 hypothetical protein (NCBI) compare
b2188 yejM -0.6 -3.9 predicted hydrolase, inner membrane (NCBI) compare
b1347 ydaC -0.6 -0.4 Rac prophage; predicted protein (NCBI) compare
b2678 proW -0.6 -3.7 glycine betaine transporter subunit (NCBI) compare
b1693 aroD -0.6 -2.9 3-dehydroquinate dehydratase (NCBI) compare
b2905 gcvT -0.6 -3.5 glycine cleavage system aminomethyltransferase T (NCBI) compare
b1677 lpp -0.6 -1.3 murein lipoprotein (NCBI) compare
b0928 aspC -0.6 -2.5 aspartate aminotransferase, PLP-dependent (NCBI) compare
b1238 tdk -0.6 -3.1 thymidine kinase (NCBI) compare
b3791 rffA -0.6 -3.4 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b4451 ryhB -0.6 -1.1 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b1074 flgC -0.6 -1.8 flagellar basal-body rod protein C (NCBI) compare
b1536 ydeI -0.6 -0.8 hypothetical protein (NCBI) compare
b1236 galU -0.6 -2.3 glucose-1-phosphate uridylyltransferase (NCBI) compare
b3786 rffE -0.6 -4.6 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b1182 hlyE -0.6 -0.4 hemolysin E (VIMSS) compare
b1984 asnW -0.6 -0.7 tRNA-Asn (NCBI) compare
b3204 ptsN -0.6 -1.9 sugar-specific enzyme IIA component of PTS (NCBI) compare
b2576 srmB -0.6 -1.5 ATP-dependent RNA helicase (NCBI) compare
b3940 metL -0.6 -3.7 bifunctional aspartate kinase II/homoserine dehydrogenase II (NCBI) compare
b0018 mokC -0.6 -0.9 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b3389 aroB -0.6 -3.6 3-dehydroquinate synthase (NCBI) compare
b1482 osmC -0.6 -1.6 osmotically inducible, stress-inducible membrane protein (NCBI) compare
b3884 yihW -0.6 -3.1 putative DEOR-type transcriptional regulator (VIMSS) compare
b2688 gshA -0.6 -3.0 glutamate--cysteine ligase (NCBI) compare
b2614 grpE -0.6 -1.4 heat shock protein (NCBI) compare
b0437 clpP -0.6 -2.7 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b3742 mioC -0.6 -1.9 flavodoxin (NCBI) compare
b0430 cyoC -0.6 -1.9 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b0688 pgm -0.6 -1.6 phosphoglucomutase (NCBI) compare
b2700 ygaD -0.6 -2.6 competence damage-inducible protein A (NCBI) compare
b1620 malI -0.6 -1.5 DNA-binding transcriptional repressor (NCBI) compare
b4509 ylcG -0.5 -1.4 DLP12 prophage; predicted protein (NCBI) compare
b3950 frwB -0.5 -1.6 predicted enzyme IIB component of PTS (NCBI) compare
b1739 osmE -0.5 -1.5 DNA-binding transcriptional activator (NCBI) compare
b0099 mutT -0.5 -2.9 nucleoside triphosphate pyrophosphohydrolase, marked preference for dGTP (NCBI) compare
b2101 yegW -0.5 -2.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b1302 puuE -0.5 -1.6 GABA aminotransferase, PLP-dependent (NCBI) compare
b1754 b1754 -0.5 -1.9 orf, hypothetical protein (VIMSS) compare
b1025 ycdT -0.5 -1.0 predicted diguanylate cyclase (NCBI) compare
b3341 rpsG -0.5 -0.5 30S ribosomal protein S7 (NCBI) compare
b1235 rssB -0.5 -3.4 response regulator of RpoS (NCBI) compare
b0432 cyoA -0.5 -3.6 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b1121 ycfZ -0.5 -1.0 predicted inner membrane protein (NCBI) compare
b1109 ndh -0.5 -1.7 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b4585 sroB -0.5 -0.8 Novel sRNA, function unknown (RefSeq) compare
b1165 ymgA -0.5 -0.3 hypothetical protein (NCBI) compare
b1612 fumA -0.5 -1.9 fumarate hydratase (fumarase A), aerobic Class I (NCBI) compare
b0921 smtA -0.5 -2.1 predicted S-adenosyl-L-methionine-dependent methyltransferase (NCBI) compare
b0784 moaD -0.5 -1.3 molybdopterin synthase, small subunit (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in phage experiments

For phage Phage across organisms